{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T06:14:19Z","timestamp":1792131259620,"version":"4.4.0"},"reference-count":19,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>Pigmentation in the head-and-neck lesions is an uncommon feature. The presence of it is fascinating, but its relevance is unknown. Various odontogenic and nonodontogenic lesions show the presence of melanin pigment. Although the presence of melanin is normal in the epithelium and connective tissue, the role of melanin pigmentation in odontogenic cysts is unclear. Apart from maintaining the skin balance, varying other functions of melanin is being researched. However, not much study has been done regarding it in odontogenic lesions. As the literature regarding such cases are scanty, here, we present a case of pigmented dentigerous cyst and an attempt to understand their relationship.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jomfp.jomfp_433_20","type":"journal-article","created":{"date-parts":[[2022,1,19]],"date-time":"2022-01-19T04:58:08Z","timestamp":1642568288000},"page":"523-526","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":4,"title":["Melanin and odontogenic cysts"],"prefix":"10.4103","volume":"25","author":[{"given":"Priyanka","family":"Nitin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"HS","family":"Sreeshyla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"GD","family":"Vidya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"BR","family":"Premalatha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-31-20240906","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1111\/j.1601-0825.1996.tb00242.x","article-title":"Pigmented lateral periodontal cyst and other pigmented odontogenic lesions","volume":"2","author":"Buchner","year":"1996","journal-title":"Oral Dis"},{"key":"R3-31-20240906","doi-asserted-by":"crossref","first-page":"398","DOI":"10.4103\/0973-029X.151325","article-title":"Pigmented odontogenic tumors: Adding color to diagnosis?","volume":"18","author":"Bhanu","year":"2014","journal-title":"J Oral Maxillofac Pathol"},{"key":"R4-31-20240906","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1002\/1097-0142(19900815)66:4<786::AID-CNCR2820660431>3.0.CO;2-0","article-title":"Melanin in a dentigerous cyst and associated adenomatoid odontogenic tumor","volume":"66","author":"Warter","year":"1990","journal-title":"Cancer"},{"key":"R5-31-20240906","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1007\/s004280000249","article-title":"Pigmented ameloblastic fibrodentinoma: A novel melanin-pigmented intraosseous odontogenic lesion","volume":"437","author":"Takeda","year":"2000","journal-title":"Virchows Arch"},{"key":"R6-31-20240906","doi-asserted-by":"crossref","first-page":"1","DOI":"10.5005\/jcdp-8-5-85","article-title":"A pigmented dentigerous cyst in a patient with multiple dentigerous cysts of the jaws: A case report","volume":"8","author":"Farahani","year":"2007","journal-title":"J Contemp Dent Pract"},{"key":"R7-31-20240906","doi-asserted-by":"crossref","first-page":"3016","DOI":"10.1038\/sj.onc.1206460","article-title":"Development of melanocyte precursors from the vertebrate neural crest","volume":"22","author":"Dupin","year":"2003","journal-title":"Oncogene"},{"key":"R8-31-20240906","doi-asserted-by":"crossref","first-page":"430","DOI":"10.3892\/mco.2013.81","article-title":"Pigmented keratocystic odontogenic tumor: A case report with review of the literature","volume":"1","author":"Ishida","year":"2013","journal-title":"Mol Clin Oncol"},{"key":"R9-31-20240906","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/0030-4220(76)90171-7","article-title":"Studies on melanocytes. V. The presence of melanocytes in the human dental primordium: An explanation for pigmented lesions of the jaws","volume":"42","author":"Lawson","year":"1976","journal-title":"Oral Surg Oral Med Oral Pathol"},{"key":"R10-31-20240906","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1186\/1746-160X-3-35","article-title":"A pigmented calcifying cystic odontogenic tumor associated with compound odontoma: A case report and review of literature","volume":"3","author":"Han","year":"2007","journal-title":"Head Face Med"},{"key":"R11-31-20240906","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/1746-160X-10-8","article-title":"Melanin: The biophysiology of oral melanocytes and physiological oral pigmentation","volume":"10","author":"Feller","year":"2014","journal-title":"Head Face Med"},{"key":"R12-31-20240906","first-page":"4183","article-title":"Synthesis and physiological implications of melanic pigments","volume":"17","author":"Maranduca","year":"2019","journal-title":"Oncol Lett"},{"key":"R14-31-20240906","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/S0301-0503(84)80248-9","article-title":"A biochemical study of the nature of jaw cysts (II). The role of lipids in the enlargement of cysts","volume":"12","author":"Suzuki","year":"1984","journal-title":"J Maxillofac Surg"},{"key":"R15-31-20240906","first-page":"1","article-title":"The role of gingival melanin pigmentation in inflammation of gingiva, based on genetic analysis","volume":"5","author":"Eid","year":"2013","journal-title":"J Int Oral Health"},{"key":"R16-31-20240906","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1902\/jop.1981.52.11.701","article-title":"Melanin pigmentation and inflammation in human gingiva","volume":"52","author":"Patsakas","year":"1981","journal-title":"J Periodontol"},{"key":"R17-31-20240906","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1111\/1523-1747.ep12709595","article-title":"Regulation of human melanocyte growth, dendricity, and melanization by keratinocyte derived factors","volume":"92","author":"Gordon","year":"1989","journal-title":"J Invest Dermatol"},{"key":"R18-31-20240906","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1016\/j.kint.2020.02.012","article-title":"The positive effect of selective prostaglandin E2 receptor EP2 and EP4 blockade on cystogenesis in vitro is counteracted by increased kidney inflammation in vivo","volume":"98","author":"Lannoy","year":"2020","journal-title":"Kidney Int"},{"key":"R19-31-20240906","doi-asserted-by":"crossref","first-page":"F1622","DOI":"10.1152\/ajprenal.00036.2007","article-title":"EP2 receptor mediates PGE2-induced cystogenesis of human renal epithelial cells","volume":"293","author":"Elberg","year":"2007","journal-title":"Am J Physiol Renal Physiol"},{"key":"R20-31-20240906","doi-asserted-by":"crossref","first-page":"e1230","DOI":"10.4317\/jced.55134","article-title":"Pigmented odontogenic keratocyst: Report of a rare case and review of the literature","volume":"10","author":"Rodrigues-Fernandes","year":"2018","journal-title":"J Clin Exp Dent"},{"key":"R21-31-20240906","doi-asserted-by":"crossref","first-page":"78","DOI":"10.4103\/jomfp.JOMFP_253_17","article-title":"Pigmented calcifying cystic odontogenic tumor associated with compound odontoma: Report of a rare case and review","volume":"23","author":"Premalatha","year":"2019","journal-title":"J Oral Maxillofac Pathol"}],"container-title":["Journal of Oral and Maxillofacial Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jomfp.jomfp_433_20","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:07:16Z","timestamp":1787166436000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jomfp.jomfp_433_20"}},"subtitle":["An ambiguous yet imperative relation"],"short-title":[],"issued":{"date-parts":[[2021,9]]},"references-count":19,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.4103\/jomfp.jomfp_433_20","relation":{},"ISSN":["0973-029X"],"issn-type":[{"value":"0973-029X","type":"print"}],"subject":[],"published":{"date-parts":[[2021,9]]}}}