{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:37:34Z","timestamp":1787841454154,"version":"build-2784847793"},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Salivary duct carcinoma (SDC) is a rare and highly aggressive malignant salivary gland neoplasm, accounting for only 0.2% of salivary gland tumours. It predominantly affects the parotid gland and represents a significant concern with limited prevalence (1\u20131.2 individuals per million). We present a case of a 65-year-old female patient with a clinical history of swelling and pain in the right lower jaw region for six months. Diagnostic investigations revealed a well-defined submandibular gland lesion. Subsequent histopathological and immunohistochemical findings confirmed the lesion to be SDC. This case report emphasises the challenges in diagnosing this aggressive malignancy, which stems from its rarity and resemblance to other neoplasms. It is worth noting that the involvement of the submandibular gland is observed in a mere 12% of SDC cases, while females account for only 25% of the reported instances.<\/jats:p>","DOI":"10.4103\/jomfp.jomfp_476_23","type":"journal-article","created":{"date-parts":[[2024,7,11]],"date-time":"2024-07-11T06:07:54Z","timestamp":1720678074000},"page":"311-314","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Salivary duct carcinoma in the submandibular gland: A rare case report with differential diagnosis"],"prefix":"10.4103","volume":"28","author":[{"given":"Geerthanaa","family":"Muthu","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Pathology, Sree Mookambika Institute of Dental Sciences, Kanyakumari District, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prasanth","family":"Thankappan","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Pathology, Sree Mookambika Institute of Dental Sciences, Kanyakumari District, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D","family":"Angelin","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Pathology, Sree Mookambika Institute of Dental Sciences, Kanyakumari District, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R","family":"Franklin","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Pathology, Sree Mookambika Institute of Dental Sciences, Kanyakumari District, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,7,11]]},"reference":[{"key":"R1-20240906","first-page":"2672772","article-title":"Salivary duct carcinoma: Case reports and brief review of the literature","author":"Kantamani","year":"2021","journal-title":"Case Rep Oncol Med 2021"},{"key":"R2-20240906","doi-asserted-by":"crossref","first-page":"354","DOI":"10.14740\/jmc3396","article-title":"Salivary duct carcinoma of submandibular gland","volume":"10","author":"Sepulveda","year":"2019","journal-title":"J Med Cases"},{"key":"R3-20240906","first-page":"e3139","article-title":"Clinicopathological behaviour and treatment-related outcome of rare salivary duct carcinoma: The Shaukat Khanum Memorial Cancer Hospital experience","volume":"10","author":"Anwer","year":"2018","journal-title":"Cureus"},{"key":"R4-20240906","doi-asserted-by":"crossref","first-page":"e0095","DOI":"10.1097\/MD.0000000000010095","article-title":"Salivary duct carcinoma of the supraglottis with a distinct presentation. A case report and literature review","volume":"97","author":"Hsu","year":"2018","journal-title":"Medicine (Baltimore)"},{"key":"R5-20240906","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1002\/cncy.22288","article-title":"Salivary duct carcinoma: updates in histology, cytology, molecular biology, and treatment","volume":"128","author":"Nakaguro","year":"2020","journal-title":"Cancer Cytopathol"},{"key":"R6-20240906","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1002\/cncy.22568","article-title":"Salivary duct carcinoma: A report of 70 FNA cases and review of the literature","volume":"130","author":"Wakely","year":"2022","journal-title":"Cancer Cytopathol"},{"key":"R7-20240906","doi-asserted-by":"crossref","first-page":"1430","DOI":"10.1002\/hed.27034","article-title":"The implicated clinical factors for outcomes in 304 patients with salivary duct carcinoma: Multi-institutional retrospective analysis in Japan","volume":"44","author":"Kusafuka","year":"2022","journal-title":"Head Neck"},{"key":"R8-20240906","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.oraloncology.2017.09.008","article-title":"Salivary duct carcinoma: An aggressive salivary gland malignancy with opportunities for targeted therapy","volume":"74","author":"Schmitt","year":"2017","journal-title":"Oral Oncol"},{"issue":"Suppl 1","key":"R9-20240906","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1007\/s12105-013-0456-x","article-title":"Salivary duct carcinoma: New developments\u2014morphological variants including pure in situ high-grade lesions;Proposed molecular classification","volume":"7","author":"Simpson","year":"2013","journal-title":"Head Neck Pathol"}],"container-title":["Journal of Oral and Maxillofacial Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jomfp.jomfp_476_23","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T13:55:56Z","timestamp":1787838956000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jomfp.jomfp_476_23"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4]]},"references-count":9,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/jomfp.jomfp_476_23","relation":{},"ISSN":["0973-029X","1998-393X"],"issn-type":[{"value":"0973-029X","type":"print"},{"value":"1998-393X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4]]},"assertion":[{"value":"2023-11-07","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-12-09","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}