{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:37:19Z","timestamp":1787841439842,"version":"build-2784847793"},"reference-count":19,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Hybrid tumours encompass lesions containing two or more pathologic entities. The pathogenesis of these lesions is barely understood and described. Juvenile trabecular ossifying fibroma (JTOF) is a benign but locally aggressive fibro-osseous neoplasm commonly affecting the maxilla of the adolescent age group. Hybrid lesions of JTOF have been reported along with central giant cell granuloma (CGCG), aneurysmal bone cyst (ABC) and traumatic bone cyst, respectively. However, the co-occurrence of JTOF with CGCG and ABC in a single patient has not yet been reported in the literature, hence, making ours the first case report of this kind. Theories describing the pathogenesis of this rare phenomenon have also been proposed and elaborated.<\/jats:p>","DOI":"10.4103\/jomfp.jomfp_554_23","type":"journal-article","created":{"date-parts":[[2024,7,11]],"date-time":"2024-07-11T06:18:33Z","timestamp":1720678713000},"page":"337-342","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Juvenile trabecular ossifying fibroma associated with central giant cell granuloma and aneurysmal bone cyst like changes \u2013 A triple hybrid tumour? Or a pathologic sequelae?"],"prefix":"10.4103","volume":"28","author":[{"given":"Revathi","family":"Krishna","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Pathology and Microbiology, Maulana Azad Institute of Dental Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Priya","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Pathology and Microbiology, Maulana Azad Institute of Dental Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sujata","family":"Mohanty","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Maulana Azad Institute of Dental Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aadithya B.","family":"Urs","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Pathology and Microbiology, Maulana Azad Institute of Dental Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,7,11]]},"reference":[{"key":"R1-20240906","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1007\/s12105-017-0794-1","article-title":"Update from the 4th edition of the World Health Organization classification of head and neck tumours: odontogenic and maxillofacial bone tumors","volume":"11","author":"Wright","year":"2017","journal-title":"Head Neck Pathol"},{"key":"R2-20240906","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1007\/s12105-021-01404-7","article-title":"Update from the 5th edition of the World Health Organization classification of head and neck tumors: odontogenic and maxillofacial bone tumours","volume":"16","author":"Vered","year":"2022","journal-title":"Head Neck Pathol"},{"key":"R3-20240906","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.clinimag.2020.01.022","article-title":"Secondary aneurysmal bone cysts and associated primary lesions: Imaging features of 49 cases","volume":"62","author":"Gutierrez","year":"2020","journal-title":"Clin Imaging"},{"key":"R4-20240906","doi-asserted-by":"crossref","first-page":"70","DOI":"10.32074\/1591-951X-213","article-title":"The 2020 WHO classification of soft tissue tumours: News and perspectives","volume":"113","author":"Sbaraglia","year":"2021","journal-title":"Pathologica"},{"key":"R5-20240906","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1080\/00016357.2020.1797160","article-title":"A systematic review of the clinical and radiographic features of hybrid central giant cell granuloma lesions of the jaws","volume":"79","author":"Alsufyani","year":"2021","journal-title":"Acta Odontol Scand"},{"key":"R6-20240906","doi-asserted-by":"crossref","first-page":"119","DOI":"10.18311\/jpfa\/2022\/29894","article-title":"A hybrid lesion of the mandible with three co-existent pathologies: Report of a rare case with literature review","volume":"36","author":"Verma","year":"2022","journal-title":"J Pierre Fauchard Acad (India Section)"},{"key":"R7-20240906","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/S0300-9785(78)80005-2","article-title":"Aneurysmal bone cyst \u2014simple bone cyst, two aspects of the same pathologic entity?","volume":"7","author":"Hillerup","year":"1978","journal-title":"Int J Oral Surg"},{"key":"R8-20240906","doi-asserted-by":"crossref","first-page":"4019","DOI":"10.1016\/S0021-9258(17)43001-8","article-title":"Paracrine interactions in bone-secreted products of osteoblasts permit osteoclasts to respond to parathyroid hormone","volume":"259","author":"Wong","year":"1984","journal-title":"J Biol Chem"},{"key":"R9-20240906","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/S0901-5027(05)80242-5","article-title":"Giant cell lesions complicating fibro-osseous conditions of the jaws","volume":"22","author":"Penfold","year":"1993","journal-title":"Int J Oral Maxillofac Surg"},{"key":"R10-20240906","doi-asserted-by":"crossref","first-page":"70","DOI":"10.4103\/2231-0746.83162","article-title":"Fibro-osseous lesions vs. central giant cell granuloma: A hybrid lesion","volume":"1","author":"Geetha","year":"2011","journal-title":"Ann Maxillofac Surg"},{"key":"R11-20240906","first-page":"1","article-title":"Case report: Rare hybrid lesion of a central giant cell granuloma within a juvenile ossifying fibroma","volume":"8","author":"Saad","year":"2019","journal-title":"F1000Res"},{"key":"R12-20240906","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1038\/sj.dmfr.4600384","article-title":"Juvenile ossifying fibroma of the mandible. An 8 year radiological follow-up","volume":"27","author":"Noffke","year":"1998","journal-title":"Dentomaxillofac Radiol"},{"key":"R13-20240906","doi-asserted-by":"crossref","first-page":"299","DOI":"10.4103\/0973-029X.86693","article-title":"\u201cHybrid\u201d lesion of the maxilla","volume":"15","author":"Sankaranarayanan","year":"2011","journal-title":"J Oral Maxillofac Pathol"},{"key":"R14-20240906","first-page":"388","article-title":"Trabecular juvenile ossifying fibroma with aneurysmal bone cyst: A rare presentation","volume":"33","author":"Silva","year":"2011","journal-title":"Pediatr Dent"},{"key":"R15-20240906","doi-asserted-by":"crossref","first-page":"e84","DOI":"10.1097\/IOP.0b013e3181eea92f","article-title":"Aneurysmal bone cyst secondary to ossifying fibroma in the orbit","volume":"27","author":"Yazici","year":"2011","journal-title":"Ophthal Plast Reconstr Surg"},{"key":"R16-20240906","doi-asserted-by":"crossref","first-page":"3450","DOI":"10.1016\/j.ejrad.2012.05.010","article-title":"Imaging study of ossifying fibroma with associated aneurysmal bone cyst in the paranasal sinus","volume":"81","author":"Yang","year":"2012","journal-title":"Eur J Radiol"},{"key":"R17-20240906","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1016\/j.ijporl.2012.12.021","article-title":"Rare pediatric presentation of aneurysmal bone cyst with trabecular juvenile ossifying fibroma and ossifying fibroma","volume":"77","author":"Urs","year":"2013","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"R18-20240906","first-page":"ZD01","article-title":"Juvenile ossifying fibroma with aneurysamal bone cyst: A case report","volume":"8","author":"Reddy","year":"2014","journal-title":"J Clin Diagnostic Res"},{"key":"R19-20240906","doi-asserted-by":"crossref","first-page":"205","DOI":"10.26502\/fjor.2644-00240039","article-title":"Juvenile trabecular ossifying fibroma (TrJOF) orginating from lateral fronto-orbital bone with secondary aneurysmal bone cyst (ABC) formation: Report of an unusual case and literature review","volume":"4","author":"Abdalla","year":"2021","journal-title":"J Ophthalmol Res"}],"container-title":["Journal of Oral and Maxillofacial Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jomfp.jomfp_554_23","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T13:55:17Z","timestamp":1787838917000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jomfp.jomfp_554_23"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4]]},"references-count":19,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/jomfp.jomfp_554_23","relation":{},"ISSN":["0973-029X","1998-393X"],"issn-type":[{"value":"0973-029X","type":"print"},{"value":"1998-393X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4]]},"assertion":[{"value":"2023-12-30","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-06-04","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}