{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T16:43:43Z","timestamp":1786725823108,"version":"build-2736575974"},"reference-count":23,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2017,5]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>The role fine-needle aspiration (FNA) in the diagnosis of salivary gland lesions has evolved over the years. Although clinical and radiological parameters help to narrow the differential diagnosis the tissue diagnosis still remains the gold standard.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>This study is from January 2013 to December 2015 in our Department of Pathology where 170 salivary gland lesions were aspirated. The aim of the present study was to analyze adequacy rate in relation to the size of lesion and to evaluate varied cytological spectrum of salivary gland lesions with emphasis on differential diagnosis and to correlate cytological diagnosis with age, gender and anatomical site.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The 170 cytological smears were categorized into two groups: Group 1 adequate aspirations (88.2%), Group 2 inadequate aspirations (11.7%). The adequate aspirations were subdivided as neoplastic (53.33%) and nonneoplastic (46.66%). The distribution of the various neoplastic lesions (80; 53.33%) were 66 (82.5%) benign, 12 (15%) were malignant and 2 (2.5%) were suspicious of malignancy. Among benign neoplasms, the pleomorphic adenoma (62; 93.3%) was the most frequent followed by Warthins tumor (4; 6%). The most common malignant neoplasms were adenoid cystic carcinoma (6; 50%), followed by mucoepidermoid carcinoma (4; 33.3%), malignant lymphoma (1; 8.3%) and metastatic carcinomatous deposits (1; 8.3%). In two cases, cytological picture indicated suspicion for malignancy however specific tumor typing could not be done. The neoplasms occurred more frequently in the parotid gland (65%), followed by submandibular gland (21.3%) and minor salivary glands (13.8%). The nonneoplastic lesions (70) included 68.6% cases of chronic sialadenitis, 17.1% cases were reported as mucocele, 11.4% cases of acute sialadenitis 2.9% cases as tubercular granulomas.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>FNA cytology provides useful information on the management of salivary gland lesions and prevents unnecessary surgery in cases of nonneoplastic lesions and identification of malignancy helps the surgeon in deciding type and extent of surgery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jomfp.jomfp_61_17","type":"journal-article","created":{"date-parts":[[2017,8,18]],"date-time":"2017-08-18T06:59:05Z","timestamp":1503039545000},"page":"203-210","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":15,"title":["Cytological spectrum of salivary gland lesions and their correlation with epidemiological parameters"],"prefix":"10.4103","volume":"21","author":[{"given":"Vaneet Kaur","family":"Sandhu","sequence":"first","affiliation":[{"name":"Department of Pathology, Guru Gobind Singh Medical College and Hospital, Faridkot, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Upender","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Pathology, Guru Gobind Singh Medical College and Hospital, Faridkot, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Navtej","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Pathology, Guru Gobind Singh Medical College and Hospital, Faridkot, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arun","family":"Puri","sequence":"additional","affiliation":[{"name":"Department of Pathology, Guru Gobind Singh Medical College and Hospital, Faridkot, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-20250523","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1002\/path.1711460106","article-title":"Salivary gland tumours. A review of 2410 cases with particular reference to histological types, site, age and sex distribution","volume":"146","author":"Eveson","year":"1985","journal-title":"J Pathol"},{"key":"R2-20250523","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1159\/000075637","article-title":"Role of fine needle aspiration cytology in the diagnosis of swellings in the salivary gland regions: A study of 712 cases","volume":"13","author":"Das","year":"2004","journal-title":"Med Princ Pract"},{"key":"R3-20250523","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.7314\/APJCP.2012.13.4.1583","article-title":"Accuracy of fine needle aspiration cytology of salivary gland lesions: Routine diagnostic experience in Bangkok, Thailand","volume":"13","author":"Nguansangiam","year":"2012","journal-title":"Asian Pac J Cancer Prev"},{"key":"R4-20250523","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1111\/j.1600-0714.2011.01069.x","article-title":"Fine-needle aspiration cytology: A reliable tool in the diagnosis of salivary gland lesions","volume":"41","author":"Singh Nanda","year":"2012","journal-title":"J Oral Pathol Med"},{"key":"R5-20250523","doi-asserted-by":"crossref","first-page":"e53","DOI":"10.1016\/j.tripleo.2006.11.017","article-title":"Salivary tumors in North Jordanians: A descriptive study","volume":"103","author":"Al-Khateeb","year":"2007","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"R6-20250523","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1590\/S0041-87812002000600005","article-title":"Salivary gland tumors in a Brazilian population: A retrospective study of 124 cases","volume":"57","author":"Vargas","year":"2002","journal-title":"Rev Hosp Clin Fac Med Sao Paulo"},{"key":"R7-20250523","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1007\/s12105-009-0139-9","article-title":"Salivary gland tumor: A review of 599 cases in a Brazilian population","volume":"3","author":"de Oliveira","year":"2009","journal-title":"Head Neck Pathol"},{"key":"R8-20250523","first-page":"62","article-title":"Salivary gland lesions: A Jamaican perspective","volume":"50","author":"Williams","year":"2001","journal-title":"West Indian Med J"},{"key":"R10-20250523","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/j.ijom.2005.02.005","article-title":"Salivary gland tumors in a Brazilian population: A retrospective study of 496 cases","volume":"34","author":"Ito","year":"2005","journal-title":"Int J Oral Maxillofac Surg"},{"key":"R11-20250523","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1002\/(SICI)1097-0339(199604)14:3<195::AID-DC1>3.0.CO;2-H","article-title":"Fine-needle sampling of salivary gland lesions. I. Cytology and histology correlation of 412 cases of pleomorphic adenoma","volume":"14","author":"Klijanienko","year":"1996","journal-title":"Diagn Cytopathol"},{"key":"R12-20250523","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1046\/j.1365-2303.1997.4375043.x","article-title":"Salivary epithelial-myoepithelial carcinoma: Report of a case misinterpreted as pleomorphic adenoma on fine needle aspiration (FNA)","volume":"8","author":"Stewart","year":"1997","journal-title":"Cytopathology"},{"key":"R13-20250523","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1002\/dc.2840060111","article-title":"Mucin production by pleomorphic adenomas of the parotid gland: A cytologic spectrum","volume":"6","author":"Stanley","year":"1990","journal-title":"Diagn Cytopathol"},{"key":"R15-20250523","first-page":"S100","article-title":"Review of fine-needle aspiration cytology of salivary gland neoplasms, with emphasis on differential diagnosis","volume":"118","author":"Mukunyadzi","year":"2002","journal-title":"Am J Clin Pathol"},{"key":"R16-20250523","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.oraloncology.2007.01.016","article-title":"Clinical analysis of salivary gland tumor cases in West China in past 50 years","volume":"44","author":"Li","year":"2008","journal-title":"Oral Oncol"},{"key":"R17-20250523","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1002\/(SICI)1097-0339(199709)17:3<230::AID-DC12>3.0.CO;2-G","article-title":"Sources of diagnostic error in the fine-needle aspiration diagnosis of Warthin's tumor and clues to a correct diagnosis","volume":"17","author":"Ballo","year":"1997","journal-title":"Diagn Cytopathol"},{"key":"R18-20250523","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1093\/ajcp\/93.1.39","article-title":"Lymphoepithelial cysts of the salivary glands. Histologic and cytologic features","volume":"93","author":"Elliott","year":"1990","journal-title":"Am J Clin Pathol"},{"key":"R19-20250523","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/S1808-8694(15)31332-X","article-title":"Epidemiologic profile of salivary gland neoplasms: Analysis of 245 cases","volume":"71","author":"Lima","year":"2005","journal-title":"Braz J Otorhinolaryngol"},{"key":"R20-20250523","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1093\/ajcp\/106.1.35","article-title":"Basal cell (monomorphic) and minimally pleomorphic adenomas of the salivary glands. Distinction from the solid (anaplastic) type of adenoid cystic carcinoma in fine-needle aspiration","volume":"106","author":"Stanley","year":"1996","journal-title":"Am J Clin Pathol"},{"key":"R21-20250523","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1054\/jcms.1999.0092","article-title":"Salivary gland tumours treated in the stomatological clinics in Bratislava","volume":"28","author":"Satko","year":"2000","journal-title":"J Craniomaxillofac Surg"},{"key":"R22-20250523","first-page":"533","article-title":"Epidemiologic profile of salivary gland neoplasms: Analysis of 245 cases","volume":"34","author":"Lima","year":"2005","journal-title":"Braz J Otorhinolaryngol"},{"key":"R23-20250523","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1002\/(SICI)1097-0339(199708)17:2<92::AID-DC3>3.0.CO;2-Q","article-title":"Fine-needle sampling of salivary gland lesions. IV. Review of 50 cases of mucoepidermoid carcinoma with histologic correlation","volume":"17","author":"Klijanienko","year":"1997","journal-title":"Diagn Cytopathol"},{"key":"R24-20250523","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1002\/dc.20353","article-title":"Fine-needle aspiration cytology of salivary glands: Diagnostic pitfalls \u2013 Revisited","volume":"34","author":"Rajwanshi","year":"2006","journal-title":"Diagn Cytopathol"},{"key":"R25-20250523","doi-asserted-by":"crossref","first-page":"32","DOI":"10.5958\/2394-6792.2016.00008.9","article-title":"Fine needle aspiration cytology of salivary gland lesions with histopathological correlation in a district hospital of Jammu region","volume":"3","author":"Gupta","year":"2016","journal-title":"Indian J Pathol Oncol"}],"container-title":["Journal of Oral and Maxillofacial Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/01233803-201721020-00007","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T16:26:09Z","timestamp":1786724769000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/01233803-201721020-00007"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,5]]},"references-count":23,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2017]]}},"URL":"https:\/\/doi.org\/10.4103\/jomfp.jomfp_61_17","relation":{},"ISSN":["0973-029X","1998-393X"],"issn-type":[{"value":"0973-029X","type":"print"},{"value":"1998-393X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,5]]},"assertion":[{"value":"2017-03-31","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-04-04","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}