{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T17:27:31Z","timestamp":1786728451734,"version":"build-2736575974"},"reference-count":34,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Context:<\/jats:title>\n                    <jats:p>Oral lichen planus (OLP) and oral lichenoid mucositis (OLM) are immune-mediated mucosal conditions with multifactorial etiology, with similar clinical and histological characteristics. Diagnosis should be confirmed considering both clinical and histological aspects. Some subsets are associated with immune-mediated thyroid dysfunction due to anti-thyroid peroxidase antibody (TPO) and anti-thyroglobulin antibody (TGA).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims:<\/jats:title>\n                    <jats:p>To ascertain the presence of thyroid autoantibodies in a cohort of patients with OLP and OLM from a South Indian population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and Materials:<\/jats:title>\n                    <jats:p>This observational study comprised 21 patients with 7 cases of OLP (Group I) and 14 cases of OLM (Group II) who reported from 2021\u20132023 for 2 years. Serum anti-thyroid antibodies including TPO and TGA was estimated using chemiluminescence immunoassay technique along with clinical and histological aspects. Altered levels of serological parameters were compared with respect to these auto-immune conditions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Increased level of thyroid autoantibodies was observed in three (42%) of the seven cases of OLP. Two cases had elevated TPO (3-4 folds) and TGA (6-38 folds) and the subjects were above 50 years. Seven (50%) of the 14 OLM cases exhibited increased thyroid autoantibody levels and were above 50 years, predominantly females. TPO levels were increased in the range of 12 to 178 and TGA from 2 to 136 folds. Duration of these lesions were more than a year.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Increased thyroid autoantibodies observed in both OLP and OLM represent an underlying autoimmune response. Long-term monitoring will enable the clinicians to correlate the antibody levels with the management of these lesions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jomfp.jomfp_85_24","type":"journal-article","created":{"date-parts":[[2024,12,31]],"date-time":"2024-12-31T08:00:50Z","timestamp":1735632050000},"page":"549-554","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Study on thyroid autoimmunity of oral lichen planus and oral lichenoid mucositis"],"prefix":"10.4103","volume":"28","author":[{"given":"C","family":"Lavanya","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Pathology, Ragas Dental College and Hospital, The Tamilnadu Dr. MGR Medical University, Chennai, Tamilnadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Ranganathan","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Pathology, Ragas Dental College and Hospital, The Tamilnadu Dr. MGR Medical University, Chennai, Tamilnadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,12,31]]},"reference":[{"issue":"s1","key":"R1-20250108","doi-asserted-by":"crossref","first-page":"S54","DOI":"10.1038\/modpathol.2016.121","article-title":"Oral lichenoid lesions: Distinguishing the benign from the deadly","volume":"30","author":"M\u00fcller","year":"2017","journal-title":"Mod Pathol"},{"key":"R2-20250108","doi-asserted-by":"crossref","first-page":"102","DOI":"10.4103\/0019-5154.147830","article-title":"Oral lichenoid lesions-a review and update","volume":"60","author":"Kamath","year":"2015","journal-title":"Indian J Dermatol"},{"key":"R3-20250108","doi-asserted-by":"crossref","first-page":"3076","DOI":"10.21037\/tcr.2020.01.51","article-title":"The natural history of oral mucosal lesions with both lichenoid and epithelial dysplastic features: A systematic review","volume":"9","author":"Raj","year":"2020","journal-title":"Transl Cancer Res"},{"key":"R4-20250108","first-page":"e938","article-title":"Oral lichen planus and its relationship with systemic diseases. 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