{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:27:38Z","timestamp":1787761658997,"version":"build-2784847793"},"reference-count":8,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>A 24-year-old male patient presented with the principal complaint of deposits on his teeth and gingival pigmentation. After examination, he was diagnosed with chronic generalized gingivitis. He was further referred for pre-procedural routine blood investigations. Bleeding time, clotting time, and his random blood sugar values were normal. CBC report revealed the presence of erythrocytosis with microcytic hypochromic red blood cells. Following this peripheral smear was taken which reveals the presence of polychromatophils, target cells and a few spherocytes. Haemoglobin electrophoresis by high-performance liquid chromatography (HPLC) was performed which disclosed 90.8% of HbE, suggestive of homozygous haemoglobinopathy. He had no other associated systemic findings, and there was no relevant family history.<\/jats:p>\n                    <jats:p>The patient was informed about his condition and stated to have pre-marital and pre-natal genetic counselling in the future. The patient being a carrier of the thalassaemic trait happened to know his condition incidentally, which could prevent future complications.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jomfp.jomfp_98_22","type":"journal-article","created":{"date-parts":[[2023,4,26]],"date-time":"2023-04-26T05:21:36Z","timestamp":1682486496000},"page":"580-582","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["HBE homozygous haemoglobinpathy \u2013 Fortuitous finding"],"prefix":"10.4103","volume":"26","author":[{"given":"V. L.","family":"Premika Sri","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Sreeja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. Sathish","family":"Muthukumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Nachiammai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Merlin","family":"Jayaraj","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. H.","family":"Harini Priya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-28-20240906","first-page":"27","article-title":"Diagnosis of the haemoglobinopathies","volume":"27","author":"Trent","year":"2006","journal-title":"Clin Biochem Rev"},{"key":"R2-28-20240906","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1586\/ehm.09.74","article-title":"Global burden, distribution and prevention of \u03b2-thalassemias and hemoglobin E disorders","volume":"3","author":"Colah","year":"2010","journal-title":"Expert Rev Hematol"},{"key":"R3-28-20240906","first-page":"17","article-title":"Prevalence of hemoglobinopathies in Manipur","volume":"14","author":"Karthika","year":"2012","journal-title":"IOSR J Dent Med Sci"},{"key":"R4-28-20240906","first-page":"66","article-title":"Hemoglobin E disorders in South Gujarat: A study of 35 cases","volume":"3","author":"Jha","year":"2012","journal-title":"Nat J Comm Med"},{"key":"R5-28-20240906","first-page":"396","article-title":"Thalassemic hemoglobinopathies","volume":"113","author":"Steinberg","year":"1983","journal-title":"Am J Pathol"},{"key":"R6-28-20240906","first-page":"5840","article-title":"A case report on HBE homozygous haemoglobinopathy","volume":"6","author":"Agarwal","year":"2015","journal-title":"Int J Recent Sci Res"},{"key":"R7-28-20240906","first-page":"532","article-title":"Hemoglobinopathies: Clinical manifestations, diagnosis, and treatment","volume":"108","author":"Kohne","year":"2011","journal-title":"Deutsches \u00c4rzteblatt Int"},{"key":"R9-28-20240906","doi-asserted-by":"crossref","first-page":"119","DOI":"10.2217\/bmm.13.103","article-title":"Advances in technologies for screening and diagnosis of hemoglobinopathies","volume":"8","author":"Traeger-Synodinos","year":"2014","journal-title":"Biomark Med"}],"container-title":["Journal of Oral and Maxillofacial Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jomfp.jomfp_98_22","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:04:14Z","timestamp":1787760254000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jomfp.jomfp_98_22"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10]]},"references-count":8,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.4103\/jomfp.jomfp_98_22","relation":{},"ISSN":["0973-029X"],"issn-type":[{"value":"0973-029X","type":"print"}],"subject":[],"published":{"date-parts":[[2022,10]]}}}