{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T20:03:52Z","timestamp":1787169832495,"version":"build-2736575974"},"reference-count":44,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:p>Infection control is essential to protect both the doctor and the patient by preventing the spread of infectious diseases. There is no exception in the field of dentistry, particularly in orthodontics, where numerous appliances are used for a variety of functions and also because the mouth cavity has the highest concentration of bacteria of any body part. Through this systematic review, we aimed to assess the various methods of sterilization employed in an orthodontic setting. Using relevant keywords, reference searches, and citation searches, the databases such as PubMed, MEDLINE, Web of Science, Cochrane, and Scopus were all searched; a total of 206 documents were found, of which 113 were initially selected. The remaining 23 distinct papers were initially made available after 90 publications that were identical to or similar to one another were eliminated. The final selection was made from eight documents that met all inclusion and exclusion requirements. The existing methods of sterilization were found to be competent in dealing with the microorganisms found in a typical orthodontic setting. The chemical method of sterilization was the norm in most of the studies that we assessed, with glutaraldehyde and peracetic acid (PAA) being the most commonly employed compounds for disinfection.<\/jats:p>\n                  <jats:sec>\n                    <jats:title>PROSPERO Registration Number:<\/jats:title>\n                    <jats:p>CRD42022380831.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jos.jos_53_23","type":"journal-article","created":{"date-parts":[[2023,9,6]],"date-time":"2023-09-06T02:15:40Z","timestamp":1693966540000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Sterilizing orthodontic appliances: A systematic review and meta-analysis on the available methods"],"prefix":"10.4103","volume":"12","author":[{"given":"Huda","family":"Abutayyem","sequence":"first","affiliation":[{"name":"Department of Clinical Sciences, Center of Medical and Bio-Allied Health Sciences Research, College of Dentistry, Ajman University, Ajman, United Arab Emirates"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad Khursheed","family":"Alam","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, Center of Medical and Bio-Allied Health Sciences Research, College of Dentistry, Ajman University, Ajman, United Arab Emirates"},{"name":"Orthodontic Division, Preventive Dentistry Department, Orthodontic Division, College of Dentistry, Jouf University, Sakaka, Saudi Arabia"},{"name":"Department of Dental Research Cell, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences. Chennai, Tamil Nadu, India"},{"name":"Department of Public Health, Faculty of Allied Health Sciences, Daffodil lnternational University, Ashulia, Dhaka, Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bushra","family":"Kanwal","sequence":"additional","affiliation":[{"name":"Orthodontic Specialist, Practicing in Dental Clinic, AlBaha, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haytham J.","family":"Alswairki","sequence":"additional","affiliation":[{"name":"School of Dental Sciences, Universiti Sains Malaysia, Kota Bharu, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yahya A.","family":"Alogaibi","sequence":"additional","affiliation":[{"name":"Orthodontic Consultant, Aseer Specialized Dental Center, Abha, Saudi 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