{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:26:36Z","timestamp":1787840796841,"version":"build-2784847793"},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 5","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Urinary tract infections are frequently caused by Gram-negative bacilli, and timely detection and management of resistant strains and their antimicrobial susceptibilities are crucial.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A six-month study examined Gram-negative bacilli from catheterized and noncatheterized patients, assessing antibiotic susceptibility, minimum inhibitory concentration, and Extended spectrum beta lactamase (ESBL) production genes using real-time Polymerase chain reaction (PCR).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Out of 72 isolates, 55.56% were ESBLs, with 65.0% from catheterized and 35.0% from noncatheterized samples. Out of 21 ESBL isolates, 47.62% had cefotaximase M (CTX-M) gene, while 4.76% had sulfhydril variant (SHV) and oxacillinase (OXA) 10\/11 genes. Coproduction of CTX-M and SHV was observed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The study reveals multiple ESBL genes co-expression in clinical isolates from catheterized and noncatheterized patients, emphasizing the need for regular monitoring and antibiotic policy development.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jpbs.jpbs_1019_24","type":"journal-article","created":{"date-parts":[[2025,1,30]],"date-time":"2025-01-30T11:04:45Z","timestamp":1738235085000},"page":"S4500-S4502","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Comparative Study of Noncatheterized and Catheter-Associated Urinary Tract Infections by ESBL-Producing Gram-Negative Bacilli in an Urban Tertiary-Care Center, Salem, Tamil Nadu"],"prefix":"10.4103","volume":"16","author":[{"given":"KT","family":"Revathi","sequence":"first","affiliation":[{"name":"Department of Microbiology, Vinayaka Mission\u2019s Kirupananda Variyar Medical College and Hospital, Vinayaka Mission\u2019s Research Foundation (Deemed to be University), Salem, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reena","family":"Rajan","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Vinayaka Mission\u2019s Kirupananda Variyar Medical College and Hospital, Vinayaka Mission\u2019s Research Foundation (Deemed to be University), Salem, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Mathavi","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Vinayaka Mission\u2019s Kirupananda Variyar Medical College and Hospital, Vinayaka Mission\u2019s Research Foundation (Deemed to be University), Salem, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"AV Raghavendra","family":"Rao","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Vinayaka Mission\u2019s Kirupananda Variyar Medical College and Hospital, Vinayaka Mission\u2019s Research Foundation (Deemed to be University), Salem, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,1,30]]},"reference":[{"key":"R1-20250130","first-page":"109","article-title":"Catheter-associated urinary tract infections:Current challenges and future prospects","volume":"14","author":"Werneburg","year":"2022","journal-title":"Res Rep Urol"},{"key":"R2-20250130","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1086\/650482","article-title":"Diagnosis, prevention, and treatment of catheter-associated urinary tract infection in adults:2009 international clinical practice guidelines from the infectious diseases society of 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tract infection:A systematic review","volume":"107","author":"Schmiemann","year":"2010","journal-title":"Dtsch Arztebl Int"},{"key":"R7-20250130","doi-asserted-by":"crossref","first-page":"4025","DOI":"10.2147\/IDR.S412350","article-title":"Extended-spectrum \u03b2-lactamase and carbapenemase-producing gram-negative bacteria and associated factors among patients suspected of community and hospital-acquired urinary tract infections at ayder comprehensive specialized hospital, Tigrai, Ethiopia","volume":"16","author":"Gebremedhin","year":"2023","journal-title":"Infect Drug Resist"},{"key":"R8-20250130","first-page":"1238","article-title":"Comparison between non catheterised and catheter associated urinary tract infections caused by extended spectrum beta lactamase producing Escherichia coli and Klebsiella pneumoniae","volume":"17","author":"Ashraf","year":"2023","journal-title":"Int J Sci 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5","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/jpbs.jpbs_1019_24","relation":{},"ISSN":["0976-4879","0975-7406"],"issn-type":[{"value":"0976-4879","type":"print"},{"value":"0975-7406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"2024-08-15","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-08-21","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}