{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:21:59Z","timestamp":1787840519426,"version":"build-2784847793"},"reference-count":7,"publisher":"Ovid Technologies (Wolters Kluwer Health)","license":[{"start":{"date-parts":[[2024,11,19]],"date-time":"2024-11-19T00:00:00Z","timestamp":1731974400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Silver diamine fluoride (SDF) has been identified as a noninvasive way to stop dental caries from becoming worse, particularly in baby teeth.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>A hundred kids between the ages of 3 and 6 who have at least one carious lesion in their primary teeth participated in a randomized controlled experiment. One of the two groups\u2014the experimental group (n = 50), which got a 38% SDF therapy, or the control group (n = 50), which received a placebo\u2014was randomly allocated to the subjects. Over the course of a year, the carious lesions received biannual applications of the SDF. The main result was the stoppage of caries, ascertained by monitoring the change of an active lesion to an inactive one using standardized digital radiographs and clinical evaluations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Only 35% of the carious lesions in the control group showed evidence of arrest after a year, compared to 87% of lesions in the experimental group (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001). It was shown that there would be one carious lesion arrested for every 2.5 patients with SDF if the number required to treat (NNT) was 2.5. During the research, no notable side effects were noted.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The remarkable efficacy of SDF in halting dental caries in primary teeth highlights its significance in the treatment of young dental patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jpbs.jpbs_1023_24","type":"journal-article","created":{"date-parts":[[2024,11,20]],"date-time":"2024-11-20T02:01:33Z","timestamp":1732068093000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Evaluation of the Effectiveness of Silver Diamine Fluoride in Arresting Caries in Primary Teeth"],"prefix":"10.4103","author":[{"given":"Nishita","family":"Garg","sequence":"first","affiliation":[{"name":"Department of Pedodontics and Preventive Dentistry, Dental Institute, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sayani","family":"Roy","sequence":"additional","affiliation":[{"name":"Department of Pedodontics and Preventive Dentistry, Dental Institute, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abhay Kumar","family":"Jain","sequence":"additional","affiliation":[{"name":"Department of Orthodontics and Dentofacial Orthopedics, Dental Institute, Rajendra Institute of Medical Sciences. Ranchi, Jharkhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tapan Kumar","family":"Mandal","sequence":"additional","affiliation":[{"name":"Department of Conservative and Endodontics, Dental Institute, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M S","family":"Girish","sequence":"additional","affiliation":[{"name":"Department of Pedodontics and Preventive Dentistry, JSS Dental College and Hospital, Affiliate to JSS Academy of Higher Education and Research, Mysuru, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Parul","family":"Priya","sequence":"additional","affiliation":[{"name":"Department of Orthodontics and Dentofacial Orthopedics, Hazaribag College of Dental Sciences and Hospital, Hazaribag, Jharkhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,11,19]]},"reference":[{"key":"R1-20250114","first-page":"93","article-title":"Clinical use of silver diamine fluoride in dental treatment","volume":"37","author":"Mei","year":"2016","journal-title":"Compend Contin Educ Dent"},{"key":"R2-20250114","first-page":"201","article-title":"Clinical trials of silver diamine fluoride in arresting caries among children: A systematic review","volume":"1","author":"Gao","year":"2016","journal-title":"JDR Clin Trans Res"},{"key":"R3-20250114","first-page":"16","article-title":"UCSF protocol for caries arrest using silver diamine fluoride: Rationale, indications and consent","volume":"44","author":"Horst","year":"2016","journal-title":"J Calif Dent Assoc"},{"key":"R4-20250114","first-page":"22","article-title":"Effectiveness of silver diamine fluoride in caries prevention and arrest: A systematic literature review","volume":"65","author":"Contreras","year":"2017","journal-title":"Gen Dent"},{"key":"R5-20250114","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1177\/0022034508329406","article-title":"Silver diamine fluoride: A caries \u201csilver-fluoride bullet","volume":"88","author":"Rosenblatt","year":"2009","journal-title":"\u201cJ Dent Res"},{"key":"R6-20250114","first-page":"466","article-title":"Silver diamine fluoride treatment considerations in children's caries management","volume":"38","author":"Crystal","year":"2016","journal-title":"Pediatr Dent"},{"key":"R7-20250114","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1159\/000478668","article-title":"Silver diamine fluoride has efficacy in controlling caries progression in primary teeth: A systematic review and meta-analysis","volume":"51","author":"Chibinski","year":"2017","journal-title":"Caries Res"}],"container-title":["Journal of Pharmacy and Bioallied Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_1023_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T13:24:23Z","timestamp":1787837063000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_1023_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,19]]},"references-count":7,"URL":"https:\/\/doi.org\/10.4103\/jpbs.jpbs_1023_24","relation":{},"ISSN":["0976-4879","0975-7406"],"issn-type":[{"value":"0976-4879","type":"print"},{"value":"0975-7406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,19]]},"assertion":[{"value":"2024-08-15","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-09-04","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}