{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:23:39Z","timestamp":1787840619848,"version":"build-2784847793"},"reference-count":15,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Fungal infections are rare occurrence in the oral cavity. They are most often seen in other medical conditions such as the immunocompromised states, diabetes, on immunosuppressants, and more recently, among the COVID patients. There are various ways that are employed to manage these infections. The most usual of fungal infection in these conditions is mucormycosis, also called as zygomycosis. Hence, in our study, we aim to evaluate the management of the fungal infection mucormycosis in trauma patients by the surgical approach.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>\n                      We piloted a retrospective observational study among 50 subjects who were admitted to the department with oral fungal infections with mucormycosis. We analyzed various clinical and demographic parameters among the subjects. The data thus obtained were analyzed with proper statistical tools deliberating\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.05 as significant.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      We observed that among the 50 subjects, the mean age was 41 \u00b1 1.7 years. There was no significant difference between the genders and the age groups. The most common reason for the oral involvement was uncontrolled diabetes. This was followed by malignancy, specifically leukemia, AIDS, and COVID. The most common site of the involvement was the palate, followed by the mandibular region. All the subjects tested positive for the fungal hyphae of\n                      <jats:italic toggle=\"yes\">Rhizopus arrhizus<\/jats:italic>\n                      which was the most common of the species. The surgical debridement along with the medical management showed satisfactory results, while one death was noted in our study.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Although rare, oral involvement in the fungal infection with the mucormycosis is often easily managed when diagnosed early. The proper surgical debridement is the best method of treatment along with the appropriate medications. The management of the underlying medical conditions is the primary key for the success of the treatments.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jpbs.jpbs_103_22","type":"journal-article","created":{"date-parts":[[2022,7,13]],"date-time":"2022-07-13T15:05:34Z","timestamp":1657724734000},"page":"S744-S747","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["A Surgical Approach in the Management of Mucormycosis in Trauma Patients"],"prefix":"10.4103","volume":"14","author":[{"given":"Karn","family":"Singh","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Government Dental College and Hospital, Afzalgunj, Hyderabad, Telangana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Jyothirmayee","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Government Dental College and Hospital, Afzalgunj, Hyderabad, Telangana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruma","family":"Rani","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Government Dental College and Hospital, Afzalgunj, Hyderabad, Telangana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N. Surya","family":"Vamshi","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Government Dental College and Hospital, Afzalgunj, Hyderabad, Telangana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariea","family":"Francis","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Government Dental College and Hospital, Afzalgunj, Hyderabad, Telangana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anagha S.","family":"Nath","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Government Dental College and Hospital, Afzalgunj, Hyderabad, Telangana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2022,7,13]]},"reference":[{"key":"R1-20250925","doi-asserted-by":"crossref","first-page":"e0179136","DOI":"10.1371\/journal.pone.0179136","article-title":"Increasing incidence of mucormycosis in a large Spanish hospital from 2007 to 2015: Epidemiology and microbiological characterization of the isolates","volume":"12","author":"Guinea","year":"2017","journal-title":"PLoS One"},{"key":"R2-20250925","doi-asserted-by":"crossref","first-page":"26","DOI":"10.3390\/jof5010026","article-title":"Global epidemiology of mucormycosis","volume":"5","author":"Prakash","year":"2019","journal-title":"J Fungi (Basel)"},{"key":"R3-20250925","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.cmi.2018.07.011","article-title":"The epidemiology and clinical manifestations of mucormycosis: A systematic review and meta-analysis of case reports","volume":"25","author":"Jeong","year":"2019","journal-title":"Clin Microbiol Infect"},{"key":"R4-20250925","doi-asserted-by":"crossref","first-page":"944.e9","DOI":"10.1016\/j.cmi.2019.11.021","article-title":"A multicentre observational study on the epidemiology, risk factors, management and outcomes of mucormycosis in India","volume":"26","author":"Patel","year":"2020","journal-title":"Clin Microbiol Infect"},{"key":"R5-20250925","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1111\/myc.12474","article-title":"Mucormycosis in Iran: A systematic review","volume":"59","author":"Vaezi","year":"2016","journal-title":"Mycoses"},{"key":"R6-20250925","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1093\/mmy\/myx017","article-title":"Diabetes mellitus as the major risk factor for mucormycosis in mexico: Epidemiology, diagnosis, and outcomes of reported cases","volume":"56","author":"Corzo-Le\u00f3n","year":"2018","journal-title":"Med Mycol"},{"key":"R7-20250925","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1111\/j.1601-0825.2007.01433.x","article-title":"Palatal zygomycosis: Experience of 21 cases","volume":"14","author":"Bonifaz","year":"2008","journal-title":"Oral Dis"},{"key":"R8-20250925","doi-asserted-by":"crossref","first-page":"192","DOI":"10.4103\/ams.ams_231_18","article-title":"Rhinocerebral mucormycosis: A prospective analysis of an effective treatment protocol","volume":"9","author":"Ramadorai","year":"2019","journal-title":"Ann Maxillofac Surg"},{"key":"R9-20250925","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1080\/23744235.2019.1645962","article-title":"Mucormycosis experience through the eyes of the laboratory","volume":"51","author":"Sa\u011f\u0131ro\u011flu","year":"2019","journal-title":"Infect Dis (Lond)"},{"key":"R10-20250925","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1086\/432579","article-title":"Epidemiology and outcome of zygomycosis: A review of 929 reported cases","volume":"41","author":"Roden","year":"2005","journal-title":"Clin Infect Dis"},{"key":"R11-20250925","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1111\/myc.12678","article-title":"Oral mucormycosis in patients with haematologic malignancies in a bone marrow transplant unit","volume":"60","author":"Cheong","year":"2017","journal-title":"Mycoses"},{"key":"R12-20250925","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1093\/mmy\/myx101","article-title":"Challenges in the diagnosis and treatment of mucormycosis","volume":"56","author":"Skiada","year":"2018","journal-title":"Med Mycol"},{"key":"R13-20250925","doi-asserted-by":"crossref","first-page":"e405","DOI":"10.1016\/S1473-3099(19)30312-3","article-title":"Global guideline for the diagnosis and management of mucormycosis: An initiative of the European confederation of medical mycology in cooperation with the mycoses study group education and research consortium","volume":"19","author":"Cornely","year":"2019","journal-title":"Lancet Infect Dis"},{"issue":"Suppl 5","key":"R14-20250925","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1111\/j.1469-0691.2009.02989.x","article-title":"Orbitomaxillary mucormycosis (zygomycosis) and the surgical approach to treatment: Perspectives from a maxillofacial surgeon","volume":"15","author":"Rapidis","year":"2009","journal-title":"Clin Microbiol Infect"},{"key":"R15-20250925","doi-asserted-by":"crossref","first-page":"e173","DOI":"10.1308\/rcsann.2016.0221","article-title":"A surgical approach in the management of mucormycosis in a trauma patient","volume":"98","author":"Zahoor","year":"2016","journal-title":"Ann R Coll Surg Engl"}],"container-title":["Journal of Pharmacy and Bioallied Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_103_22","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T13:26:03Z","timestamp":1787837163000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_103_22"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7]]},"references-count":15,"journal-issue":{"issue":"Suppl 1","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.4103\/jpbs.jpbs_103_22","relation":{},"ISSN":["0976-4879","0975-7406"],"issn-type":[{"value":"0976-4879","type":"print"},{"value":"0975-7406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,7]]},"assertion":[{"value":"2022-01-20","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-01-23","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}