{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:44:56Z","timestamp":1787071496356,"version":"build-2736575974"},"reference-count":7,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 4","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>This observational study evaluated the correlation between median lobe size assessed by digital rectal examination (DRE) and the severity of lower urinary tract symptoms (LUTS) in benign prostatic hyperplasia (BPH) patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A total of 120 men aged \u226550 years were assessed using the International Prostate Symptom Score (IPSS) and DRE for median lobe grading. Correlations were analyzed using Spearman\u2019s coefficient and ANOVA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Larger median lobe size significantly correlated with higher LUTS severity (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001), with mean IPSS scores of 7.6 (small), 15.4 (moderate), and 24.1 (large lobes).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Median lobe enlargement is associated with severe LUTS in BPH, highlighting the importance of thorough clinical prostate evaluation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jpbs.jpbs_1096_25","type":"journal-article","created":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T08:01:17Z","timestamp":1766044877000},"page":"S3081-S3083","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["An Observational Study to Correlate Severity of Lower Urinary Tract Symptoms and Size of Median Lobe of Prostate by Digital Rectal Examination in Patients with Benign Prostate Hyperplasia"],"prefix":"10.4103","volume":"17","author":[{"given":"Ashish K.","family":"Dubey","sequence":"first","affiliation":[{"name":"Department of Surgery, Govt. Bundelkhand Medical College, Sagar, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aashutosh","family":"Asati","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Shyam Shah Medical College, Rewa, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mayank","family":"Chourasia","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Atal Bihari Vajpayee Government Medical College, Vidisha, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hemal","family":"Vithani","sequence":"additional","affiliation":[{"name":"Department of Surgery, Bundelkhand Medical College, Sagar, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Talha","family":"Saad","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Bundelkhand Medical College, Sagar, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abhay S.","family":"Tirkey","sequence":"additional","affiliation":[{"name":"Department of Medicine, Bundelkhand Medical College, Sagar, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uppal R.","family":"Kunkal","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Bundelkhand Medical College, Sagar, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,12,17]]},"reference":[{"issue":"Suppl 9","key":"R1-20251218","first-page":"S3","article-title":"Benign prostatic hyperplasia: An overview","volume":"7","author":"Roehrborn","year":"2005","journal-title":"Rev Urol"},{"issue":"5 Suppl","key":"R2-20251218","first-page":"S122","article-title":"BPH: Epidemiology and comorbidities","volume":"12","author":"McVary","year":"2006","journal-title":"Am J Manag Care"},{"key":"R3-20251218","first-page":"513","article-title":"Use of digital rectal examination in the primary care setting: A national survey","volume":"146","author":"Naslund","year":"1991","journal-title":"J Urol"},{"key":"R4-20251218","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1046\/j.1464-410X.2003.04088.x","article-title":"Correlation of intravesical prostatic protrusion with bladder outlet obstruction","volume":"91","author":"Chia","year":"2003","journal-title":"BJU Int"},{"key":"R5-20251218","first-page":"439","article-title":"Relationship between intravesical prostatic protrusion and bladder outlet obstruction","volume":"78","author":"Ozdemir","year":"2011","journal-title":"Urology"},{"key":"R6-20251218","first-page":"664","article-title":"Clinical significance of median lobe enlargement in BPH","volume":"181","author":"Ku","year":"2009","journal-title":"J Urol"},{"key":"R7-20251218","first-page":"1770","article-title":"Transition zone index as a predictor of outcome following prostatectomy","volume":"154","author":"Kaplan","year":"1995","journal-title":"J Urol"}],"container-title":["Journal of Pharmacy and Bioallied Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_1096_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:46:59Z","timestamp":1787068019000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_1096_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":7,"journal-issue":{"issue":"Suppl 4","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/jpbs.jpbs_1096_25","relation":{},"ISSN":["0976-4879","0975-7406"],"issn-type":[{"value":"0976-4879","type":"print"},{"value":"0975-7406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"2025-06-18","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-20","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}