{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:35:57Z","timestamp":1787070957560,"version":"build-2736575974"},"reference-count":7,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 3","license":[{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>To assess and contrast the impact of glutathione (GSH) and potassium iodide (KI) on tooth discoloration brought on by silver diamine fluoride (SDF) treatment on primary incisors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>Standardized 2 mm \u00d7 2 mm (depth \u00d7 width) of cavities were made on labial surface of each specimen, and artificial caries was created on 40 extracted primary incisors and divided into four groups based on the solution used as follows: group 1 \u2013 SDF, group 2 \u2013 SDF + saturated KI, group 3 \u2013 SDF + GSH, and group 4 \u2013 distilled water. The color assessment was recorded on days 1, 7, and 14 by using a spectrophotometer.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      SDF caused maximum staining. Staining in groups 2 and 3 was significantly less (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.05) compared to SDF, while group 3 showed the least staining at days 1 and 7, but the staining increased gradually and had no statistical difference at 14 days when compared to group 2.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The use of GSH along with SDF helps in reducing the discoloration.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jpbs.jpbs_1101_25","type":"journal-article","created":{"date-parts":[[2025,9,8]],"date-time":"2025-09-08T19:00:14Z","timestamp":1757358014000},"page":"S2724-S2726","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["An In-vitro Assessment of Potassium Iodide and Glutathione on Color Change Caused by Silver Diamine Fluoride Treatment"],"prefix":"10.4103","volume":"17","author":[{"given":"Chavva Lakshmi Charan","family":"Reddy","sequence":"first","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics, Panineeya Institute of Dental Sciences and Research Centre, Hyderabad, Telangana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sumit Nagaraj","family":"Ede","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics, Dr. Z. A. Dental College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Priyanka Padmasai","family":"Bandhakavi","sequence":"additional","affiliation":[{"name":"Intern, Vokkaligara Sangha Dental College and Hospital, Bengaluru, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shumayla","family":"Khan","sequence":"additional","affiliation":[{"name":"Consultant Pediatric and Preventive Dentist, GKS Dental Clinic, Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K Vishnu","family":"Prasad","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics, Chettinad Dental College and Research Institute, Kancheepuram, Kelambakkam, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gururaj","family":"Gunjalli","sequence":"additional","affiliation":[{"name":"Department of Pediatric and Preventive Dentistry, Surendra Dental College and Research Institute, Sri Ganganagar, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hasina","family":"Khan","sequence":"additional","affiliation":[{"name":"Consultant Pediatric and Preventive Dentist, Hyderabad, Telangana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,9,8]]},"reference":[{"key":"R1-20250930","doi-asserted-by":"crossref","first-page":"1103386","DOI":"10.3389\/fped.2023.1103386","article-title":"Case Report: Treatment and management of a child at high risk of caries","volume":"11","author":"Fan","year":"2023","journal-title":"Front Pediatr"},{"key":"R2-20250930","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1038\/sj.ebd.6400697","article-title":"Which filling material is best in the primary dentition?","volume":"11","author":"Uribe","year":"2010","journal-title":"Evid Based Dent"},{"key":"R3-20250930","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.identj.2023.10.013","article-title":"Silver compounds for caries management","volume":"74","author":"Xu","year":"2024","journal-title":"Int Dent J"},{"key":"R4-20250930","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1111\/idj.12207","article-title":"Prevention of secondary caries by silver diamine fluoride","volume":"66","author":"Mei","year":"2016","journal-title":"Int Dent J"},{"key":"R5-20250930","first-page":"745","article-title":"Inhibition of biofilm formation and antibacterial properties of a silver nano-coating on human dentine","volume":"8","author":"Besinis","year":"2014","journal-title":"Nanotoxicology"},{"key":"R6-20250930","first-page":"248","article-title":"Silver diamine fluoride, potassium iodide, and esthetic perception: An in vitro pilot study","volume":"29","author":"Miller","year":"2016","journal-title":"Am J Dent"},{"key":"R7-20250930","doi-asserted-by":"crossref","first-page":"1322","DOI":"10.3390\/ijms19051322","article-title":"Effect of glutathione bio-molecule on tooth discoloration associated with silver diammine fluoride","volume":"19","author":"Sayed","year":"2018","journal-title":"Int J Mol Sci"}],"container-title":["Journal of Pharmacy and Bioallied Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_1101_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:39:34Z","timestamp":1787067574000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_1101_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9]]},"references-count":7,"journal-issue":{"issue":"Suppl 3","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/jpbs.jpbs_1101_25","relation":{},"ISSN":["0976-4879","0975-7406"],"issn-type":[{"value":"0976-4879","type":"print"},{"value":"0975-7406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,9]]},"assertion":[{"value":"2025-06-20","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-28","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}