{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:24:45Z","timestamp":1787772285922,"version":"build-2784847793"},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Antimicrobial endodontic intracanal medicaments play a vital role along with biomechanical preparation in the elimination of bacteria present in the pulp area to achieve success in endodontic therapy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>\n                      The present research was conducted with the objective of evaluating and comparing intracanal medicaments regarding antibacterial properties against\n                      <jats:italic toggle=\"yes\">Enterococcus faecalis<\/jats:italic>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>\n                      One hundred and twenty healthy human premolars of the mandible were used. All premolar crowns were removed, keeping the standardized length of the root as 15 mm. Category 1 received triple antibiotic paste (TAP) (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 30), Category 2 received double antibiotic paste (DAP) (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 30), Category 3 received augmentin (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 30), and Category 4 received calcium hydroxide (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 30). Hygienic paper points were placed in each root canal, then they were moved to a tube containing 1 mL of brain-heart infusion medium and left there for bacteriological testing. Colony-forming units (CFUs) of\n                      <jats:italic toggle=\"yes\">E. faecalis<\/jats:italic>\n                      were then observed and counted after the plates had been incubated overnight at a temperature of 37\u00b0C.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      During intracategory comparisons, there was a significant reduction in colonies of\n                      <jats:italic toggle=\"yes\">E. feacilis<\/jats:italic>\n                      in each category (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2264 0.001). When there were intercategory comparisons, there was a maximum reduction in CFU in specimens of Category 1 (TAP) followed by Category 3 (Augmentin) and Category 2 (DAP).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>\n                      Intracanal medicaments like TAP, DAP, and augmentin are effective against root canal\n                      <jats:italic toggle=\"yes\">E. faecalis<\/jats:italic>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jpbs.jpbs_110_24","type":"journal-article","created":{"date-parts":[[2024,4,25]],"date-time":"2024-04-25T06:01:55Z","timestamp":1714024915000},"page":"S2162-S2164","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Assessment of Long-Term Success and Survival Rates of Different Types of Intracanal Medicaments"],"prefix":"10.4103","volume":"16","author":[{"given":"Akshata","family":"Ron","sequence":"first","affiliation":[{"name":"Department of Dentistry, KLE, Jagadguru Gangadhar Mahaswamigalu Moorusavirmath Medical College, Hubballi, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debkant","family":"Jena","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics, Kalinga Institute of Dental Sciences, KIIT University, Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vartul","family":"Dwivedi","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics, People\u2019s Dental Academy, Bhopal, MP, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Durgesh Kumar","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Community Medicine, Gandhi Medical College and Hospital, Bhopal, MP, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laxmikant","family":"Late","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics, Dr. DY Patil Dental College and Hospital, Dr. DY Patil Vidyapeeth, Pune, Maharastra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ankur","family":"Jethlia","sequence":"additional","affiliation":[{"name":"Department of Maxillofacial Surgery and Diagnostic Sciences, Diagnostic Division, College of Dentistry, Jazan University, Jazan, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramanpal Singh","family":"Makkad","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine and Radiology, New Horizon Dental College and Research Institute, Sakri, Bilaspur, Chhattisgarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,4,24]]},"reference":[{"key":"R1-20240829","doi-asserted-by":"crossref","first-page":"49","DOI":"10.22159\/ijap.2019.v11s1.164","article-title":"Effect of triple antibiotic paste, calcium hydroxide, ledermix on viability of pulp mesenchymal stem cells","volume":"11","author":"Prasanti","year":"2019","journal-title":"Int J App Pharm"},{"key":"R2-20240829","first-page":"e38829","article-title":"Comparative evaluation of dentinal defects after root canal preparation using various nickel titanium files:An in vitro study","volume":"15","author":"Batra","year":"2023","journal-title":"Cureus"},{"key":"R3-20240829","doi-asserted-by":"crossref","first-page":"1372","DOI":"10.1016\/j.joen.2012.06.018","article-title":"Direct effect of intracanal medicaments on survival of stem cells of the apical papilla","volume":"38","author":"Ruparel","year":"2012","journal-title":"J 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papilla cells after treatment with a 3-antibiotic mixture","volume":"40","author":"Phumpatrakom","year":"2014","journal-title":"J Endod"},{"key":"R8-20240829","first-page":"e40367","article-title":"Implications of ChatGPT in public health dentistry:A systematic review","volume":"15","author":"Tiwari","year":"2023","journal-title":"Cureus"},{"key":"R9-20240829","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.1016\/j.joen.2010.03.031","article-title":"Tooth discoloration of immature permanent incisor associated with triple antibiotic therapy:A case report","volume":"36","author":"Kim","year":"2010","journal-title":"J Endod"}],"container-title":["Journal of Pharmacy and Bioallied Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_110_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T18:35:55Z","timestamp":1787769355000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_110_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,24]]},"references-count":9,"journal-issue":{"issue":"Suppl 3","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/jpbs.jpbs_110_24","relation":{},"ISSN":["0976-4879","0975-7406"],"issn-type":[{"value":"0976-4879","type":"print"},{"value":"0975-7406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,24]]},"assertion":[{"value":"2024-02-16","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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