{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:43:09Z","timestamp":1787071389258,"version":"build-2736575974"},"reference-count":6,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T00:00:00Z","timestamp":1765584000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,4]]},"abstract":"\n Myopia, usually called shortsightedness, is the maximum common vicinity eye sickness within facet the globe with good sized social, educational, and monetary impact. As per Ayurveda, myopia can be correlated with\n Pratham Patalagata Timira<\/jats:italic>\n presenting symptoms of blurred vision, squinting, eye rubbing, and impaired vision. Even though ophthalmology has advanced significantly in the modern era, there is currently no effective and widely recognized treatment for myopia. Existing treatment for myopia correction leads to corneal scarring, corneal infections from contact lens use, and persistent ocular haze from refractive surgery. Many local therapeutic procedures like\n Nasya, Anjana, Akshi-tarpana,<\/jats:italic>\n etc., have been advised for the management of\n Timira<\/jats:italic>\n with its published clinical evidence. However, this procedures needs to be done under experts vigilance on regular basis which sometimes is not friendly with patients times, convenience, routine, cost etc. Present protocol put up oral administration of\n Chakshushya ghruta<\/jats:italic>\n (medicated ghee prepared from ingredients beneficial to eyes) instead of established procedures of\n Kriyakalpa<\/jats:italic>\n (local procedures of eyes). It is framed with the objective to observe comparative efficacy of\n Timirghnatraifalam Ghruta<\/jats:italic>\n verses\n Triphaladi Ghruta<\/jats:italic>\n systemically together with\n Padabhyanga<\/jats:italic>\n (foot massage) in management of non-pathological myopia.\n <\/jats:p>","DOI":"10.4103\/jpbs.jpbs_1198_25","type":"journal-article","created":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T16:03:29Z","timestamp":1765814609000},"page":"153-155","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Protocol of Comparative Efficacy of the Timirghnatraifalam Ghruta verses Triphaladi Ghruta Systemically Together with Padabhyanga in the Control of Non-Pathological Myopia"],"prefix":"10.4103","volume":"18","author":[{"given":"Amit","family":"Chandankhede","sequence":"first","affiliation":[{"name":"Department of Shalakya Tantra, Mahatma Gandhi Ayurved College Hospital and Research Center, Salod (H) Wardha, Datta Meghe Institute of Medical Sciences, Wardha, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roshna","family":"Bhutada","sequence":"additional","affiliation":[{"name":"Department of Shalakya Tantra, Shri K R. Pandav Ayurved College and Hospital, Nagpur, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Praveena","family":"Kher","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Jawaharlal Nehru Medical College Wardha Datta Meghe Institute of Scientific Sciences, Wardha, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,12,13]]},"reference":[{"key":"R1-20260330","first-page":"99.2","article-title":"Myopia","volume":"6","author":"Baird","year":"2020","journal-title":"Nat Rev Dis Prim"},{"key":"R3-20260330","doi-asserted-by":"crossref","first-page":"481","DOI":"10.23958\/ijirms\/vol02-i01\/08","article-title":"Clinical study on simple myopia with reference to the effect of Triphala Ghreeta","volume":"2","author":"Biswal1","year":"2017","journal-title":"Int J Innov Res Med Sci (IJIRMS)"},{"key":"R6-20260330","author":"Kaiyadevanighantu","year":"2006"},{"key":"R7-20260330","doi-asserted-by":"crossref","first-page":"9420029","DOI":"10.26599\/FMH.2025.9420029","article-title":"Protective benefits and mechanisms of Phyllanthus emblica Linn. on aging induced by oxidative stress: A system review","volume":"2","author":"Wu","year":"2025","journal-title":"Food Med Homol"},{"key":"R8-20260330","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1016\/j.jep.2018.07.014","article-title":"Neuroprotective effect of Asparagus racemosus root extract via the enhancement of brain-derived neurotrophic factor and estrogen receptor in ovariectomized rats","volume":"225","author":"Lalert","year":"2018","journal-title":"J Ethnopharmacol"},{"key":"R9-20260330","doi-asserted-by":"crossref","first-page":"1277180","DOI":"10.3389\/fmed.2023.1277180","article-title":"Reduction of experimental ocular axial elongation by neuregulin-1 antibody","volume":"10","author":"Shi","year":"2023","journal-title":"Front Med Sec"}],"container-title":["Journal of Pharmacy and Bioallied Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_1198_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:45:25Z","timestamp":1787067925000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_1198_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,13]]},"references-count":6,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/jpbs.jpbs_1198_25","relation":{},"ISSN":["0976-4879","0975-7406"],"issn-type":[{"value":"0976-4879","type":"print"},{"value":"0975-7406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,13]]},"assertion":[{"value":"2025-07-10","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-14","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}