{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:23:18Z","timestamp":1787772198743,"version":"build-2784847793"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:p>Ameloblastic carcinoma is a rare malignant odontogenic tumor that is further classified into being primary or secondary arising from a preexisting benign ameloblastoma. It affects the mandible in two thirds of the patients. There is no standard treatment protocol for this lesion but radicalsurgical excision with or without radiotherapy is reported in the majority of cases. In this paper, we present a case of a 22 year old male diagnosed with Ameloblastic carcinoma of the mandible with a clinical course of typical aggressiveness and extensive destruction. Histopathological examination of the incised biopsy showed a parakeratinized stratified squamous epithelium with underlying fibrous connective tissue stroma. The stroma is highly myxomatous and exhibits islands of odontogenic epithelium and chronic inflammatory cell infiltrates. Interlacing strands of odontogenic epithelium shows stellate reticulum-like cells and occasional areas of squamous metaplasia with cellular and nuclear pleomorphism. In addition, mitotic figures were noted. With the correlation of clinical, radiographic, and histological features, the lesion is diagnosed as ameloblastic carcinoma. The lesion was surgical excised and post-treatment follow-up for 6 months revealed no recurrence of the malignancy.<\/jats:p>","DOI":"10.4103\/jpbs.jpbs_1204_23","type":"journal-article","created":{"date-parts":[[2024,4,16]],"date-time":"2024-04-16T09:18:45Z","timestamp":1713259125000},"page":"S1867-S1870","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Ameloblastic Carcinoma in a Young Adult Male Patient - A Case Report"],"prefix":"10.4103","volume":"16","author":[{"given":"Kandasamy","family":"Murugan","sequence":"first","affiliation":[{"name":"Research Scholar, Bharath Institute of Higher Education and Research (BIHER), Chennai, Tamil Nadu, India"},{"name":"Department of Oral Medicine and Radiology, Rajas Dental College and Hospital, Kavalkinaru, Tirunelveli District, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kesavaram","family":"Padmavathy","sequence":"additional","affiliation":[{"name":"Professor, Department of Microbiology, Research Laboratory for Oral and Systemic Health, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research (BIHER), Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janardhanam","family":"Dineshshankar","sequence":"additional","affiliation":[{"name":"Professor, Department of Oral and Maxillofacial Pathology and Microbiology, Vivekanandha Dental College for Women, Thiruchengode, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saravanna","family":"Bharathi","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine and Radiology, Rajas Dental College and Hospital, Kavalkinaru, Tirunelveli District, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,4,16]]},"reference":[{"key":"R1-20240829","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1016\/0030-4220(87)90063-6","article-title":"Ameloblasticcarcinoma:a clinicopathologic study and assessment of eight cases","volume":"64","author":"Corio","year":"1987","journal-title":"Oral Surg Oral Med Oral Pathol"},{"key":"R4-20240829","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1007\/s12105-021-01404-7","article-title":"Update from the 5th edition of the world health organization classification of head and neck tumors:Odontogenic and maxillofacial bone tumours","volume":"16","author":"Vered","year":"2022","journal-title":"Head Neck Pathol"},{"key":"R5-20240829","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1177\/10668969221122993","article-title":"Milestones in the history of ameloblastic carcinoma","volume":"31","author":"Ide","year":"2023","journal-title":"Int J Surg Pathol"},{"key":"R7-20240829","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1016\/j.tripleo.2009.06.045","article-title":"Ameloblastic carcinoma:an analysis of 6 cases with review of the literature","volume":"108","author":"Yoon","year":"2009","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"R8-20240829","first-page":"e17","article-title":"Ameloblastic carcinoma of maxilla:Case report and review of the literature","volume":"104","author":"Benlyazid","year":"2007","journal-title":"Oral Surg"},{"key":"R9-20240829","doi-asserted-by":"crossref","first-page":"775707","DOI":"10.3389\/froh.2021.775707","article-title":"Malignant odontogenic tumours:A systematic review of cases reported in literature","volume":"2","author":"Marin","year":"2021","journal-title":"Front Oral Health"},{"key":"R10-20240829","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.oraloncology.2017.12.018","article-title":"Reconnoitre ameloblastic carcinoma:A prognostic update","volume":"77","author":"Saluja","year":"2018","journal-title":"Oral Oncol"},{"key":"R11-20240829","first-page":"573","article-title":"Ameloblastic carcinoma:Case report and literature review","volume":"69","author":"Avon","year":"2003","journal-title":"J Can Dent Assoc"},{"key":"R12-20240829","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1186\/s40902-023-00380-y","article-title":"Ameloblastic carcinoma of the mandible:A case report","volume":"45","author":"Ogane","year":"2023","journal-title":"Maxillofac Plast Reconstr Surg"},{"key":"R13-20240829","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1016\/j.tripleo.2006.11.048","article-title":"Ameloblastic carcinoma:an analysis of 14 cases","volume":"103","author":"Hall","year":"2007","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"}],"container-title":["Journal of Pharmacy and Bioallied Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_1204_23","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T18:32:46Z","timestamp":1787769166000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_1204_23"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4]]},"references-count":10,"journal-issue":{"issue":"Suppl 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