{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T15:10:05Z","timestamp":1783955405614,"version":"3.55.0"},"reference-count":8,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,7]]},"abstract":"\n A\n BSTRACT<\/jats:sc>\n <\/jats:title>\n \n Background:<\/jats:title>\n Rational drug use in obstetrics is essential to ensure maternal safety and optimal pregnancy outcomes. Drug utilization studies help evaluate prescribing patterns and identify areas for improvement.<\/jats:p>\n <\/jats:sec>\n \n Objective:<\/jats:title>\n To assess the drug utilization pattern and evaluate maternal outcomes associated with obstetric medications in antenatal and postnatal women at a tertiary care hospital.<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n \n A prospective observational study was conducted over six months in a tertiary care hospital. A total of 200 antenatal and postnatal women receiving medications were included. Data on demographics, drug prescriptions, and maternal outcomes were collected. Statistical analysis was performed using SPSS version 25.0. Chi-square test, independent\n t<\/jats:italic>\n -test, and multivariate logistic regression were applied. A\n P<\/jats:italic>\n value < 0.05 was considered statistically significant.\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n The mean age was 26.8 \u00b1 4.2 years. The average number of drugs prescribed per patient was 5.2 \u00b1 1.3. Iron supplements (92%) and folic acid (89%) were the most commonly prescribed drugs. Favorable maternal outcomes were observed in 88% of cases. Multivariate analysis revealed antihypertensive use (AOR = 3.56,\n P<\/jats:italic>\n = 0.001), polypharmacy (AOR = 2.83,\n P<\/jats:italic>\n = 0.006), primigravidity (AOR = 2.14,\n P<\/jats:italic>\n = 0.047), and antibiotic use (AOR = 1.89,\n P<\/jats:italic>\n = 0.041) as independent predictors of complications.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Although maternal outcomes were largely favorable, polypharmacy and high-risk drug use were significantly associated with complications. Rational prescribing practices should be emphasized.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/jpbs.jpbs_124_26","type":"journal-article","created":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T22:02:36Z","timestamp":1783720956000},"page":"227-229","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Drug Utilization Pattern and Maternal Outcomes of Obstetric Medications in Antenatal and Postnatal Women at a Tertiary Care Hospital"],"prefix":"10.4103","volume":"18","author":[{"given":"A.","family":"Saridha Prema","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynaecological Nursing, Paavai College Nursing and Research, Namakkal, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. D.","family":"Kavitha","sequence":"additional","affiliation":[{"name":"Department of Community Health Nursing, Bapuji College of Nursing, Shimoga, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Padmavathi","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecological Nursing, Dhanvantri College of Nursing, Namakkal, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,7,10]]},"reference":[{"key":"R1-20260713","article-title":"Guide to Good Prescribing: A Practical Manual","author":"De","year":"1994","journal-title":"World Health Organization"},{"key":"R2-20260713","doi-asserted-by":"crossref","first-page":"277","DOI":"10.4103\/0019-5359.26602","article-title":"Drug utilization pattern during pregnancy in North India","volume":"60","author":"Sharma","year":"2006","journal-title":"Indian J Med Sci"},{"key":"R3-20260713","doi-asserted-by":"crossref","first-page":"78","DOI":"10.4103\/0976-0105.121650","article-title":"Drug utilization in emergency medicine department at a tertiary care teaching hospital: A prospective study","volume":"4","author":"Malhotra","year":"2013","journal-title":"J Basic Clin Pharm"},{"key":"R4-20260713","doi-asserted-by":"crossref","first-page":"2650","DOI":"10.18203\/2320-1770.ijrcog20182466","article-title":"Study of drug utilization pattern in gynecology department of tertiary care hospital of Rajasthan, India","volume":"7","author":"Sharma","year":"2018","journal-title":"Int J Reprod Contracept Obstet Gynecol"},{"key":"R5-20260713","first-page":"2470","article-title":"Awareness of mothers and doctors about drug utilization pattern for illnesses encountered during pregnancy","volume":"7","author":"Kureshee","year":"2013","journal-title":"J Clin Diagn Res"},{"key":"R6-20260713","doi-asserted-by":"crossref","first-page":"4240","DOI":"10.3390\/molecules27134240","article-title":"Ziziphus nummularia: A Comprehensive Review of Its Phytochemical Constituents and Pharmacological Properties","volume":"27","author":"Mesmar","year":"2022","journal-title":"Molecules"},{"key":"R7-20260713","year":"2002","journal-title":"Promoting Rational Use of Medicines: Core Components"},{"key":"R8-20260713","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1186\/1471-2393-8-24","article-title":"Drug-prescribing patterns during pregnancy in the tertiary care hospitals of Pakistan: A cross sectional study","volume":"8","author":"Rohra","year":"2008","journal-title":"BMC Pregnancy Childbirth"}],"container-title":["Journal of Pharmacy and Bioallied Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.4103\/jpbs.jpbs_124_26","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T15:00:45Z","timestamp":1783954845000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/10.4103\/jpbs.jpbs_124_26"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":8,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/jpbs.jpbs_124_26","relation":{},"ISSN":["0976-4879","0975-7406"],"issn-type":[{"value":"0976-4879","type":"print"},{"value":"0975-7406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"2026-04-01","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-19","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}