{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:17:30Z","timestamp":1787761050334,"version":"build-2784847793"},"reference-count":6,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T00:00:00Z","timestamp":1771027200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>To evaluate the efficacy of 0.5% Bupivacaine and 4% Articaine when administered via inferior alveolar nerve block (IANB) in patients undergoing surgical management of mandibular fractures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and Method:<\/jats:title>\n                    <jats:p>The sample consisted of 40 participants, who required management of mandibular fractures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Patients receiving Bupivacaine required rescue analgesia significantly later (10.40 h) compared to those receiving Articaine (7.30 h), with a mean difference of 3.10 h (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001). This 42% delay in rescue analgesic requirement represents a clinically meaningful improvement in postoperative pain management, potentially reducing overall analgesic consumption and associated side effects while improving patient satisfaction scores.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jpbs.jpbs_1268_25","type":"journal-article","created":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T14:00:27Z","timestamp":1771077627000},"page":"141-143","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Evaluation of Efficacy of Bupivacaine vs Articaine for Postoperative Pain Management in Open Reduction of Fracture of Mandible- an in vivo study"],"prefix":"10.4103","volume":"18","author":[{"given":"Ajay K.","family":"Pillai","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, People\u2019s Dental Academy, Bhopal, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dheeraj","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, People\u2019s Dental Academy, Bhopal, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neha","family":"Jain","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, People\u2019s Dental Academy, Bhopal, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annant","family":"Choubey","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, People\u2019s Dental Academy, Bhopal, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pushpraj","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, People\u2019s Dental Academy, Bhopal, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saksham","family":"Nahar","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, People\u2019s Dental Academy, Bhopal, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,2,14]]},"reference":[{"key":"R1-20260330","doi-asserted-by":"crossref","first-page":"689","DOI":"10.53350\/pjmhs2023173689","article-title":"Efficacy of bupivacaine inferior alveolar nerve block versus intravenous use of tramadol for postoperative pain control in mandibular parasymphysis fractures","volume":"17","author":"Khan","year":"2023","journal-title":"Pak J Med Health Sci"},{"key":"R2-20260330","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1001\/jamafacial.2015.1011","article-title":"Reporting of postoperative pain management protocols in randomized clinical trials of mandibular fracture repair: A systematic review","volume":"17","author":"Butts","year":"2015","journal-title":"JAMA Facial Plast Surg"},{"key":"R3-20260330","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1111\/idj.12060","article-title":"Efficacy and safety of bupivacaine versus lidocaine in dental treatments: A meta-analysis of randomised controlled trials","volume":"64","author":"Su","year":"2014","journal-title":"Int Dent J"},{"key":"R4-20260330","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1038\/s41405-021-00082-5","article-title":"Articaine in dentistry: An overview of the evidence and meta-analysis of the latest randomised controlled trials on articaine safety and efficacy compared to lidocaine for routine dental treatment","volume":"7","author":"Martin","year":"2021","journal-title":"BDJ Open"},{"key":"R5-20260330","first-page":"172","article-title":"Efficacy of bilateral mental nerve block with bupivacaine for postoperative pain control in mandibular parasymphysis fractures","volume":"8","author":"Mesgarzadeh","year":"2014","journal-title":"J Dent Res Dent Clin Dent Prospects"},{"key":"R6-20260330","doi-asserted-by":"crossref","first-page":"253","DOI":"10.22312\/sdusbed.1062096","article-title":"A comparison of the postoperative pain relief and clinical local anesthetic efficacy of levobupivacaine and articaine for impacted lower third molar removal","volume":"13","author":"Erg\u00fcder","year":"2022","journal-title":"S\u00fcleyman Demirel \u00dcniversitesi Sa\u011fl\u0131k Bilimleri Dergisi"}],"container-title":["Journal of Pharmacy and Bioallied Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_1268_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:17:34Z","timestamp":1787757454000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_1268_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,14]]},"references-count":6,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/jpbs.jpbs_1268_25","relation":{},"ISSN":["0976-4879","0975-7406"],"issn-type":[{"value":"0976-4879","type":"print"},{"value":"0975-7406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,14]]},"assertion":[{"value":"2025-07-22","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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