{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:26:44Z","timestamp":1787840804984,"version":"build-2784847793"},"reference-count":19,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 5","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:p>Dentigerous cysts frequently develop as odontogenic cysts in the oral cavity that can occasionally progress to neoplasms. Tumor from dentigerous cysts is uncommon, with only 42 occurrences documented in the literature. This case report describes a 73-year-old male who developed primary intraosseous squamous cell carcinoma after a dentigerous cyst. The dental practitioner should have knowledge of the potential for malignant transformation in asymptomatic dentigerous cysts and ensure thorough follow-up. Even if the lesion appears benign, it is recommended to perform a complete histological investigation. Histopathological investigations have revealed malignancies in the follicle that surrounds the dental crown. While malignant lesion formation is uncommon, it should be considered a differential diagnosis in appropriate circumstances.<\/jats:p>","DOI":"10.4103\/jpbs.jpbs_1291_24","type":"journal-article","created":{"date-parts":[[2025,1,30]],"date-time":"2025-01-30T11:05:49Z","timestamp":1738235149000},"page":"S4921-S4924","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["The Unforeseen Revelation of Dentigerous Cyst"],"prefix":"10.4103","volume":"16","author":[{"given":"E","family":"Rajesh","sequence":"first","affiliation":[{"name":"Department of Oral Pathology and Microbiology, Sree Balaji Dental College and Hospitals (SBDCH), Oral Cancer Prevention Awareness and Research (COCPAR), Bharath University (BIHER), Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Dhivyadharshini","sequence":"additional","affiliation":[{"name":"Department of Oral Pathology and Microbiology, Sree Balaji Dental College and Hospitals (SBDCH), Oral Cancer Prevention Awareness and Research (COCPAR), Bharath University (BIHER), Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N Aravindha","family":"Babu","sequence":"additional","affiliation":[{"name":"Department of Oral Pathology and Microbiology, Sree Balaji Dental College and Hospitals (SBDCH), Oral Cancer Prevention Awareness and Research (COCPAR), Bharath University (BIHER), Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Ramya","sequence":"additional","affiliation":[{"name":"Department of Oral Pathology and Microbiology, Sree Balaji Dental College and Hospitals (SBDCH), Oral Cancer Prevention Awareness and Research (COCPAR), Bharath University (BIHER), Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,1,30]]},"reference":[{"key":"R1-20250130","doi-asserted-by":"crossref","DOI":"10.1007\/s12663-022-01718-1","article-title":"Primary intraosseous squamous cell carcinoma arising in dentigerous cyst:A case report and review of literature","author":"Yamagata","year":"2023","journal-title":"J Maxillofac Oral Surg"},{"key":"R2-20250130","first-page":"543","article-title":"Squamous cell carcinoma developing in a dentigerous cyst:A rare case report and review of literature","volume":"25","author":"Arora","year":"2021","journal-title":"J Oral Maxillofac Pathol"},{"key":"R3-20250130","first-page":"84","article-title":"Rare association of squamous cell carcinoma and dentigerous cyst:A case report with review of literature","volume":"10","author":"Gupta","year":"2020","journal-title":"J Oral Biol Craniofac Res"},{"key":"R4-20250130","first-page":"563","article-title":"Primary intraosseous squamous cell carcinoma arising from a dentigerous cyst:Case report and literature review","volume":"120","author":"Akbulut","year":"2019","journal-title":"J Stomatol Oral Maxillofac Surg"},{"key":"R5-20250130","first-page":"1949.e1","article-title":"Squamous cell carcinoma arising in a dentigerous cyst associated with an impacted mandibular third molar:A case report","volume":"76","author":"Bajpai","year":"2018","journal-title":"J Oral Maxillofac Surg"},{"key":"R6-20250130","first-page":"323","article-title":"Primary intraosseous carcinoma arising from an odontogenic cyst:A case report and review of the literature","volume":"21","author":"Lo Muzio","year":"2017","journal-title":"J Oral Maxillofac Pathol"},{"key":"R7-20250130","first-page":"1","article-title":"Primary intraosseous carcinoma arising in odontogenic cysts:A systematic review of clinicopathological and radiological features","volume":"47","author":"More","year":"2017","journal-title":"Imaging Sci Dent"},{"key":"R8-20250130","first-page":"592","article-title":"WHO classification of odontogenic tumors. A commentary on the Second Edition","volume":"46","author":"Gardner","year":"2017","journal-title":"Int J Oral Maxillofac Surg"},{"key":"R9-20250130","first-page":"13","article-title":"Primary intraosseous carcinoma arising in a dentigerous cyst:Report of a rare case and review of literature","volume":"10","author":"Rathore","year":"2016","journal-title":"J Clin Diagn Res"},{"key":"R10-20250130","first-page":"327","article-title":"Odontogenic and nonodontogenic cysts of the jaw:A review of the literature","volume":"56","author":"Cicci\u00f9","year":"2020","journal-title":"Medicina (Kaunas)"},{"key":"R11-20250130","first-page":"2536","article-title":"Carcinomas arising in odontogenic cysts:A systematic review","volume":"68","author":"Tosios","year":"2010","journal-title":"J Oral Maxillofac Surg"},{"key":"R13-20250130","first-page":"96","article-title":"Squamous cell carcinoma arising in a dentigerous cyst:A rare entity","volume":"9","author":"Gupta","year":"2018","journal-title":"Natl J Maxillofac Surg"},{"key":"R14-20250130","first-page":"578","article-title":"Squamous cell carcinoma arising from an odontogenic cyst:Case report and literature review","volume":"60","author":"Casaroto","year":"2018","journal-title":"J Oral Sci"},{"key":"R15-20250130","first-page":"283","article-title":"Primary intraosseous squamous cell carcinoma involving the mandible:A case report and literature review","volume":"124","author":"Boffano","year":"2017","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol"},{"key":"R16-20250130","first-page":"795","article-title":"An analysis of oral and maxillofacial pathology found in adults over a 30-year period","volume":"47","author":"Jones","year":"2018","journal-title":"J Oral Pathol Med"},{"key":"R18-20250130","first-page":"623","article-title":"Ameloblastoma","volume":"43","author":"Mendenhall","year":"2020","journal-title":"Am J Clin Oncol"},{"key":"R19-20250130","first-page":"98","article-title":"Carcinomas arising in odontogenic cysts:An analysis of 72 cases","volume":"77","author":"Carter","year":"2019","journal-title":"J Oral Maxillofac Surg"},{"key":"R20-20250130","first-page":"1168","article-title":"Carcinoma arising in odontogenic cysts:Report of two cases with review of the literature","volume":"9","author":"Panda","year":"2017","journal-title":"J Clin Exp Dent"},{"key":"R21-20250130","first-page":"663","article-title":"Malignant transformation in odontogenic cysts","volume":"70","author":"Dos Santos","year":"2017","journal-title":"J Clin Pathol"}],"container-title":["Journal of Pharmacy and Bioallied Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_1291_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T13:29:18Z","timestamp":1787837358000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_1291_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":19,"journal-issue":{"issue":"Suppl 5","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/jpbs.jpbs_1291_24","relation":{},"ISSN":["0976-4879","0975-7406"],"issn-type":[{"value":"0976-4879","type":"print"},{"value":"0975-7406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"2024-09-13","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-26","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}