{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:34:31Z","timestamp":1787762071919,"version":"build-2784847793"},"reference-count":30,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims and Objectives:<\/jats:title>\n                    <jats:p>To determine the choroidal thickness (mainly subfoveal) using spectral domain optical coherence tomography (SD-OCT) in amblyopic eyes and to compare it with the choroidal thickness (CT) of healthy fellow eyes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>In this prospective study, 140 eyes of 70 patients (aged 5\u201340 years) with strabismic and anisometropic amblyopia were examined using enhanced depth imaging (EDI) mode in SD-OCT. The CT was measured directly below the fovea and six other locations: 500 \u03bc, 1000 \u03bc, and 1500 \u03bc from fovea in both nasal and temporal quadrants.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The mean age of the patients was 22.5 \u00b1 11.2 years. The mean Best Corrected Visual Acuity (BCVA) in the amblyopic eyes was 0.87 \u00b1 0.47 logMAR and 0 \u00b1 0.02 logMAR in control eyes. The average subfoveal CT was 341.73 \u00b1 60.39 \u03bcm in the amblyopic eyes and 314.77 \u00b1 48.12 \u03bcm in the fellow eyes. Subgroup analysis showed that the patients with anisometropic amblyopia had a significantly thicker choroid as compared to the fellow healthy eyes (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.00), whereas in strabismic amblyopic eyes, this difference was not significantly significant (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.064).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Significant choroidal thickening was observed in subjects with amblyopia, which may contribute to the amblyopia pathogenesis and this could be used as a diagnostic parameter for amblyopia. These changes were more pronounced in patients with anisometropic amblyopia than strabismic amblyopia.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jpbs.jpbs_132_23","type":"journal-article","created":{"date-parts":[[2023,7,12]],"date-time":"2023-07-12T02:07:37Z","timestamp":1689127657000},"page":"S1257-S1261","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Choroidal Thickness in Patients with Unilateral Amblyopia and Comparison between Anisometropic and Strabismic Amblyopia: A Prospective Cross-Sectional Study"],"prefix":"10.4103","volume":"15","author":[{"given":"Priyanka","family":"Arora","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Dayanand Medical College and Hospital, Ludhiana, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashima","family":"Goyal","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Dayanand Medical College and Hospital, Ludhiana, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madhushmita","family":"Mahapatra","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Dayanand Medical College and Hospital, Ludhiana, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamaldeep","family":"Arora","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Dayanand Medical College and Hospital, Ludhiana, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ritesh","family":"Verma","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Dayanand Medical College and Hospital, Ludhiana, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,7,11]]},"reference":[{"key":"R1-20240829","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1093\/oxfordjournals.aje.a113627","article-title":"The evolving concept of amblyopia:A challenge to epidemiologists","volume":"118","author":"Hillis","year":"1983","journal-title":"Am J Epidemiol"},{"key":"R2-20240829","first-page":"1704","article-title":"Amblyopia:A multidisciplinary approach. 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