{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T23:56:40Z","timestamp":1793923000760,"version":"4.8.0"},"reference-count":7,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 4","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Dark-colored gingiva is an esthetic concern that cannot be ignored, especially when accompanied by a high lip line or gummy smile. Gingival depigmentation is a periodontal plastic surgical procedure, wherein the hyperpigmentation is removed or reduced by various techniques.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>This split-mouth randomized clinical trial was conducted on 20 patients aged between 18 and 45 years with maxillary physiological gingival pigmentation classes (II), (III), and (IV) according to the Dummett\u2013Gupta Oral Pigmentation Index (40 treated sites). The maxilla was randomly divided into two symmetrical parts\u2014from the right second premolar to the midline and from the midline to the left second premolar\u2014to receive either BlueM gel or COE-PAK as a dressing after surgical depigmentation with a scalpel. Indices assessed were healing index and re-epithelization index with toluidine blue, and the follow-up period was one month.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The result of the study demonstrated that pain score and re-epithelization score were less in the test group (BlueM gel) as compared to the control group (COE-PAK) and was statistically significant.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>It can be concluded that BlueM gel can also be a better alternative as a periodontal dressing compared to COE-PAK due to its properties of better healing and decreasing postoperative pain.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jpbs.jpbs_1367_25","type":"journal-article","created":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T08:00:49Z","timestamp":1766044849000},"page":"S3307-S3309","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Comparative Assessment of Efficacy of \u201cBLUEM\u201d Active Oxygen Gel and COE-PAK Dressing on Postoperative Healing After Surgical Depigmentation\u2014A Split Mouth Study"],"prefix":"10.4103","volume":"17","author":[{"given":"Jaishree","family":"Garg","sequence":"first","affiliation":[{"name":"Department of Periodontology, Institute of Dental Sciences, Bareilly, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Somya","family":"Tiwari","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Institute of Dental Sciences, Bareilly, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saurabh","family":"Sinha","sequence":"additional","affiliation":[{"name":"Department of Dentistry, KMC Medical College, Mahrajganj, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamim","family":"Ahmad","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Institute of Dental Sciences, Bareilly, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Indrani","family":"Bharadwaj","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Institute of Dental Sciences, Bareilly, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Radhika","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Institute of Dental Sciences, Bareilly, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,12,17]]},"reference":[{"key":"R1-20251218","doi-asserted-by":"crossref","first-page":"586","DOI":"10.4103\/0972-124X.142450","article-title":"Evaluation of patient response and recurrence of pigmentation following gingival depigmentation using laser and scalpel technique: A clinical study","volume":"18","author":"Grover","year":"2014","journal-title":"J Indian Soc Periodontol"},{"key":"R2-20251218","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1177\/00220345450240010701","article-title":"Clinical observations on pigment variations in healthy oral tissues of the Negro","volume":"24","author":"Dummett","year":"1945","journal-title":"J Dent Res"},{"key":"R3-20251218","first-page":"84","article-title":"An insight into gingival depigmentation techniques: The pros and cons","volume":"12","author":"Alasmari","year":"2018","journal-title":"Int J Health Sci (Qassim)"},{"key":"R4-20251218","first-page":"79","article-title":"Gingival esthetics by depigmentation","volume":"1","author":"Malhotra","year":"2014","journal-title":"J Periodontal Med Clin Pract"},{"key":"R5-20251218","doi-asserted-by":"crossref","first-page":"614","DOI":"10.4103\/0972-124X.106933","article-title":"Treatment of gingival gingival hyperpigmentation with rotary abrasive, scalpel, and laser techniques. A case series","volume":"16","author":"Murthy","year":"2012","journal-title":"J Indian Soc Periodontol"},{"key":"R6-20251218","first-page":"162","article-title":"Management of gingival hyperpigmentation by surgical abrasion: Report of three cases","volume":"18","author":"Mokeem","year":"2006","journal-title":"Saudi Dent J"},{"key":"R7-20251218","doi-asserted-by":"crossref","first-page":"139","DOI":"10.5005\/jcdp-6-3-139","article-title":"Anterior esthetic gingival depigmentation and crown lengthening: Report of a case","volume":"6","author":"Roshna","year":"2005","journal-title":"J Contemp Dent Pract"}],"container-title":["Journal of Pharmacy and Bioallied Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_1367_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:46:27Z","timestamp":1787067987000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_1367_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":7,"journal-issue":{"issue":"Suppl 4","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/jpbs.jpbs_1367_25","relation":{},"ISSN":["0976-4879","0975-7406"],"issn-type":[{"value":"0976-4879","type":"print"},{"value":"0975-7406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"2025-08-04","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-19","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}