{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T23:18:18Z","timestamp":1793229498121,"version":"4.5.0"},"reference-count":7,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 4","license":[{"start":{"date-parts":[[2025,11,19]],"date-time":"2025-11-19T00:00:00Z","timestamp":1763510400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Crestal bone loss is a critical determinant of long-term implant success. The choice of surgical technique\u2014flapless versus flapped\u2014may influence peri-implant bone preservation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To compare the crestal bone loss around dental implants placed using the flapless technique versus the conventional flapped technique over a 6-month follow-up period.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>\n                      A prospective, randomized clinical trial was conducted involving 40 systemically healthy patients requiring single-tooth implants in the posterior mandible. Participants were randomly assigned to two groups: Group A (flapless technique,\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 20) and Group B (flapped technique,\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 20). Standardized periapical radiographs were taken at baseline, 3 months, and 6 months to assess marginal bone loss. Crestal bone levels were measured mesially and distally using calibrated digital software. The primary outcome was mean crestal bone loss. Data were analyzed using paired and unpaired\n                      <jats:italic toggle=\"yes\">t<\/jats:italic>\n                      -tests.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      At 6 months, the mean crestal bone loss in Group A was 0.48 \u00b1 0.16 mm, while Group B showed 0.82 \u00b1 0.21 mm. The difference between groups was statistically significant (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt;0.001). Intragroup analysis revealed significant bone loss from baseline to 6 months in both groups (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt;0.05), but bone preservation was significantly better in the flapless group.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The flapless implant placement technique demonstrated significantly reduced crestal bone loss compared to the flapped approach. Minimally invasive protocols may contribute to better preservation of peri-implant tissues in suitable clinical scenarios.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jpbs.jpbs_1368_25","type":"journal-article","created":{"date-parts":[[2025,11,19]],"date-time":"2025-11-19T16:00:32Z","timestamp":1763568032000},"page":"S2959-S2961","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Comparative Study of Crestal Bone Loss Around Implants Placed Using Flapless Versus Flapped Technique"],"prefix":"10.4103","volume":"17","author":[{"given":"Ambrapali","family":"Surendra","sequence":"first","affiliation":[{"name":"Department of Dentistry, KLE JGMM Medical College and Hospital, Hubbali, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brijesh","family":"Byrappa","sequence":"additional","affiliation":[{"name":"Department of Dentistry, Dental Experts Dental Clinic, Bengaluru, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debeshwari","family":"Ningombam","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics, Mansarovar Dental College, Bhopal, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Shrunga","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Vokkaligara Sangha Dental College, Bengaluru, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krishan","family":"Yadav","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Jaipur Dental College, Jaipur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charudutt","family":"Patil","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics and Implantology, Saraswati Dhanwantari Dental College and Hospital, Parbhani, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,11,19]]},"reference":[{"key":"R1-20251218","first-page":"43","article-title":"Optimizing esthetics for implant restorations in the anterior maxilla: Anatomic and surgical considerations","volume":"19","author":"Buser","year":"2004","journal-title":"Int J Oral Maxillofac Implants"},{"key":"R2-20251218","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1034\/j.1600-0501.2001.120603.x","article-title":"Biologic width around one- and two-piece titanium implants","volume":"12","author":"Hermann","year":"2001","journal-title":"Clin Oral Implants Res"},{"key":"R3-20251218","first-page":"1258","article-title":"Influence of flapless or open-flap technique on healing after peri-implant bone augmentation with a xenograft: An experimental study in dogs","volume":"26","author":"Bengazi","year":"2015","journal-title":"Clin Oral Implants Res"},{"key":"R4-20251218","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.tripleo.2006.11.034","article-title":"Flapless implant surgery: An experimental study","volume":"104","author":"Jeong","year":"2007","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"R5-20251218","doi-asserted-by":"crossref","first-page":"e91","DOI":"10.1902\/jop.2013.130481","article-title":"The effect of flapless surgery on implant survival and marginal bone level: A systematic review and meta-analysis","volume":"85","author":"Lin","year":"2014","journal-title":"J Periodontol"},{"key":"R6-20251218","first-page":"424","article-title":"Endosseous implants and the periodontal patient","volume":"17","author":"Scortecci","year":"1997","journal-title":"Int J Periodontics Restorative Dent"},{"key":"R7-20251218","first-page":"753","article-title":"Flapless implant surgery in the esthetic zone: A report of 6 consecutive cases","volume":"17","author":"Campelo","year":"2002","journal-title":"Int J Oral Maxillofac Implants"}],"container-title":["Journal of Pharmacy and Bioallied Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_1368_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:43:40Z","timestamp":1787067820000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_1368_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,19]]},"references-count":7,"journal-issue":{"issue":"Suppl 4","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/jpbs.jpbs_1368_25","relation":{},"ISSN":["0976-4879","0975-7406"],"issn-type":[{"value":"0976-4879","type":"print"},{"value":"0975-7406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,19]]},"assertion":[{"value":"2025-08-04","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-19","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}