{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T20:41:03Z","timestamp":1786653663413,"version":"build-2736575974"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 4","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:p>\n                    Infertility in patients with reduced ovarian reserve and thin endometrial lining continues to pose a great challenge for successful\n                    <jats:italic toggle=\"yes\">in vitro<\/jats:italic>\n                    fertilization. In the present case, a patient with a thin endometrium and low ovarian reserve resulted in a positive pregnancy with a specific IVF treatment plan. It included plasma-rich growth factors, growth hormone, supplementation along with some interventional support of endometrial scratching, and assisted hatching. Endometrial scratching and assisted hatching further optimized implantation potential. The use of these interventions hence promoted successful implantation of the embryo that contributed to positive pregnancy outcome and the birth of a healthy baby at 39 weeks. This case showed how individual ongoing comprehensive treatments definitively made a huge difference in the success of reproductive medicine.\n                  <\/jats:p>","DOI":"10.4103\/jpbs.jpbs_1399_24","type":"journal-article","created":{"date-parts":[[2024,12,27]],"date-time":"2024-12-27T00:04:11Z","timestamp":1735257851000},"page":"S4017-S4020","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Enhancing IVF Success in Challenging Infertility Cases: The Role of PRGF, GH, and Endometrial Optimization"],"prefix":"10.4103","volume":"16","author":[{"given":"Sudhanshu","family":"Dakre","sequence":"first","affiliation":[{"name":"Department of Clinical Embryology, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jarul","family":"Shrivastava","sequence":"additional","affiliation":[{"name":"Department of Clinical Embryology, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Namrata","family":"Anjankar","sequence":"additional","affiliation":[{"name":"Department of Clinical Embryology, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deepti","family":"Shrivastava","sequence":"additional","affiliation":[{"name":"Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aakash","family":"More","sequence":"additional","affiliation":[{"name":"Department of Clinical Embryology, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shradha M.","family":"Ulhe","sequence":"additional","affiliation":[{"name":"Department of Clinical Embryology, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,12,5]]},"reference":[{"key":"R1-20241227","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1001\/jama.2021.4788","article-title":"Diagnosis and management of infertility:A review","volume":"326","author":"Carson","year":"2021","journal-title":"JAMA"},{"key":"R2-20241227","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/j.ajog.2020.10.019","article-title":"Bacterial vaginosis and its association with infertility, endometritis, and pelvic inflammatory disease","volume":"224","author":"Ravel","year":"2021","journal-title":"Am J Obstet Gynecol"},{"key":"R3-20241227","first-page":"538","article-title":"Endometritis - diagnosis, treatment and its impact on fertility - A scoping review","volume":"26","author":"Singh","year":"2022","journal-title":"JBRA Assist Reprod"},{"key":"R4-20241227","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1016\/j.fertnstert.2020.12.010","article-title":"Endometrial causes of recurrent pregnancy losses:endometriosis, adenomyosis, and chronic endometritis","volume":"115","author":"Pirtea","year":"2021","journal-title":"Fertil Steril"},{"key":"R5-20241227","first-page":"e26623","article-title":"Potential of plasma rich in growth factors (PRGF-endoret) to enhance the efficacy of assisted reproductive techniques in refractory cases","volume":"14","author":"Agirregoikoa","year":"2022","journal-title":"Cureus"},{"key":"R6-20241227","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3310\/JNZT9406","article-title":"Endometrial scratch to increase live birth rates in women undergoing first-time in vitro fertilisation:RCT and systematic review","volume":"26","author":"Metwally","year":"2022","journal-title":"Health Technol Assess"},{"key":"R7-20241227","doi-asserted-by":"crossref","first-page":"124","DOI":"10.4274\/jtgga.galenos.2020.2019.0175","article-title":"Endometrial \u201cscratching\u201dan update and overview of current research","volume":"21","author":"G\u00fcnther","year":"2020","journal-title":"J Turk-Ger Gynecol Assoc"},{"key":"R8-20241227","doi-asserted-by":"crossref","first-page":"1269382","DOI":"10.3389\/fendo.2024.1269382","article-title":"New advances in the treatment of thin endometrium","volume":"15","author":"Wang","year":"2024","journal-title":"Front Endocrinol"},{"key":"R9-20241227","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1016\/j.tjog.2021.01.034","article-title":"Chronic endometritis impairs embryo implantation in patients with repeated implantation failure:A retrospective study","volume":"61","author":"Li","year":"2022","journal-title":"Taiwan J Obstet Gynecol"},{"issue":"Suppl 1","key":"R10-20241227","doi-asserted-by":"crossref","first-page":"dead093.267","DOI":"10.1093\/humrep\/dead093.267","article-title":"O-221 Regenerative endometrial PRGF (plasma rich in growth factors) treatment in patients with thin endometrium, recurrent implantation failure, and recurrent miscarriages:A retrospective, self-controlled, cohort study","volume":"38","author":"Bodri","year":"2023","journal-title":"Hum Reprod"}],"container-title":["Journal of Pharmacy and Bioallied Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_1399_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:40:39Z","timestamp":1786650039000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_1399_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":10,"journal-issue":{"issue":"Suppl 4","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/jpbs.jpbs_1399_24","relation":{},"ISSN":["0976-4879","0975-7406"],"issn-type":[{"value":"0976-4879","type":"print"},{"value":"0975-7406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"2024-10-04","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-17","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}