{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:30:34Z","timestamp":1787841034702,"version":"build-2784847793"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 4","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:p>The paper describes the treatment of a 27-year-old woman with a history of infertility, heavy menstrual periods, and severe endometriosis with bilateral hydrosalpinx. The patient received hormonal treatment with triptorelin acetate, a GnRH agonist, to treat her endometriosis and regulate her menstruation. Hysterosalpingography confirmed the presence of bilateral hydrosalpinx, thus suggesting IVF as the most suitable method to conceive. The patient went through a long protocol using GnRH agonist and 14 oocytes were retrieved from her with 10 being fertilized. To avoid ovarian hyperstimulation syndrome (OHSS), all the embryos were frozen and thawed after six months of hormone replacement therapy for the preparation of the endometrium, and a single blastocyst was transferred. The patient conceived, and a subsequent \u03b2-hCG level of 256 mIU\/mL proved good pregnancy status 14 days after the embryo transfer. This case demonstrates how a personalized and holistic treatment approach to the management of infertility, especially in patients with such conditions as endometriosis and hydrosalpinx, can be very fruitful.<\/jats:p>","DOI":"10.4103\/jpbs.jpbs_1400_24","type":"journal-article","created":{"date-parts":[[2024,12,6]],"date-time":"2024-12-06T07:00:14Z","timestamp":1733468414000},"page":"S4013-S4016","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["The Role of GnRH Agonist Therapy and Hysterosalpingography (HSG) in Diagnosing and Treating Tubal Factor Infertility"],"prefix":"10.4103","volume":"16","author":[{"given":"Dipti","family":"Katre","sequence":"first","affiliation":[{"name":"Department of Biochemistry, Dr. Ulhas Patil Medical College and Hospital, Jalgaon, Aurangadbad, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Namrata","family":"Choudhary","sequence":"additional","affiliation":[{"name":"Department of Clinical Embryology, School of Allied Health Sciences, Datta Meghe Institute of Higher Education and Research, Sawangi, Wardha, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashish Prakash","family":"Anjankar","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Sawangi, Wardha Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aakash","family":"More","sequence":"additional","affiliation":[{"name":"Department of Clinical Embryology, School of Allied Health Sciences, Datta Meghe Institute of Higher Education and Research, Sawangi, Wardha, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sudhanshu","family":"Dakre","sequence":"additional","affiliation":[{"name":"Department of Clinical Embryology, School of Allied Health Sciences, Datta Meghe Institute of Higher Education and Research, Sawangi, Wardha, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,12,5]]},"reference":[{"key":"R1-20241227","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1001\/jama.2021.4788","article-title":"Diagnosis and management of infertility:A review","volume":"326","author":"Carson","year":"2021","journal-title":"JAMA"},{"key":"R2-20241227","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1016\/j.fertnstert.2017.01.017","article-title":"Obesity and female infertility:Potential mediators of obesity's impact","volume":"107","author":"Broughton","year":"2017","journal-title":"Fertil Steril"},{"key":"R3-20241227","doi-asserted-by":"crossref","first-page":"994","DOI":"10.3390\/jcm12030994","article-title":"Three types of endometriosis:Pathogenesis, diagnosis and treatment. State of the art","volume":"12","author":"Imperiale","year":"2023","journal-title":"J Clin Med"},{"key":"R4-20241227","doi-asserted-by":"crossref","first-page":"1020827","DOI":"10.3389\/fendo.2022.1020827","article-title":"Endometriosis-associated infertility:From pathophysiology to tailored treatment","volume":"13","author":"Bonavina","year":"2022","journal-title":"Front Endocrinol"},{"key":"R5-20241227","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1097\/GRF.0000000000000292","article-title":"Medical management of endometriosis","volume":"60","author":"Rafique","year":"2017","journal-title":"Clin Obstet Gynecol"},{"key":"R6-20241227","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1055\/s-0040-1722155","article-title":"Effects of hydrosalpinx on endometrial implantation failures:Evaluating salpingectomy in women undergoing in vitro fertilization","volume":"43","author":"Palagiano","year":"2021","journal-title":"Rev Bras Ginecol E Obstetr\u00edcia RBGO Gynecol Obstet"},{"key":"R7-20241227","doi-asserted-by":"crossref","first-page":"948","DOI":"10.3390\/diagnostics13050948","article-title":"Transvaginal ultrasound accuracy in the hydrosalpinx diagnosis:A systematic review and meta-analysis","volume":"13","author":"Delgado-Morell","year":"2023","journal-title":"Diagnostics (Basel)"},{"key":"R8-20241227","doi-asserted-by":"crossref","first-page":"2730","DOI":"10.1093\/humrep\/dew210","article-title":"Pregnancy outcome in women with endometriosis achieving pregnancy with IVF","volume":"31","author":"Benaglia","year":"2016","journal-title":"Hum Reprod"},{"key":"R9-20241227","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1097\/AOG.0000000000001005","article-title":"Abnormal placentation:Placenta previa, vasa previa, and placenta accreta","volume":"126","author":"Silver","year":"2015","journal-title":"Obstet Gynecol"},{"key":"R10-20241227","doi-asserted-by":"crossref","first-page":"720401","DOI":"10.3389\/fmed.2021.720401","article-title":"Comparison of hysterosalpingography with laparoscopy in the diagnosis of tubal factor of female infertility","volume":"8","author":"Tan","year":"2021","journal-title":"Front Med"}],"container-title":["Journal of Pharmacy and Bioallied Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_1400_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T13:39:22Z","timestamp":1787837962000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_1400_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":10,"journal-issue":{"issue":"Suppl 4","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/jpbs.jpbs_1400_24","relation":{},"ISSN":["0976-4879","0975-7406"],"issn-type":[{"value":"0976-4879","type":"print"},{"value":"0975-7406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"2024-10-04","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-17","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}