{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:44:44Z","timestamp":1787071484104,"version":"build-2736575974"},"reference-count":8,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 4","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,12]]},"abstract":"\n Introduction:<\/jats:title>\n Oral submucous fibrosis (OSMF) is a persistent, potentially cancerous condition that affects 6.42 out of every 1000 people in South Asia. It causes burning sensation, limited mouth opening, and fibrosis. This study compares the efficacy of Emblica officinalis and Curcumin longa, two potent herbal antioxidants, in managing OSMF symptoms.<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods:<\/jats:title>\n \n Sixty clinically diagnosed OSMF patients were equally divided into Groups A and B who received Emblica officinalis and Curcumin longa respectively (i.e., twice daily for 2 months). Data was analyzed using the Chi-square and Student\u2019s paired\n t<\/jats:italic>\n -test (\n P<\/jats:italic>\n < 0.05).\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n Group A showed greater reduction in oral burning (Visual Analogue Scale scores), while Group B exhibited significant improvement in mouth opening.<\/jats:p>\n <\/jats:sec>\n \n Discussion:<\/jats:title>\n Curcumin longa was more effective in improving mouth opening and reducing fibrous bands, for treating OSMF-related structural and functional deficits. Emblica officinalis offered more relief from the burning sensation, indicating its importance in symptomatic therapy.<\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n A combination therapy may offer a more holistic approach. Future research should explore nanoparticle formulations of Curcumin longa and Emblica officinalis to enhance their therapeutic potential in OSMF and fibrosis.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/jpbs.jpbs_1426_25","type":"journal-article","created":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T08:01:25Z","timestamp":1766044885000},"page":"S3367-S3369","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Efficacy of Emblica Officinalis and Curcumin Longa, Two Significant Herbal Antioxidants, in the Management of OSMF: A Comparative Cross-sectional Study"],"prefix":"10.4103","volume":"17","author":[{"given":"Annette M.","family":"Bhambal","sequence":"first","affiliation":[{"name":"Department of Oral Medicine and Radiology, People\u2019s College of Dental Sciences and Research Centre, Bhopal, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Parnavi","family":"Mishra","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine and Radiology, People\u2019s College of Dental Sciences and Research Centre, Bhopal, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sudhanshu","family":"Saxena","sequence":"additional","affiliation":[{"name":"Department of Dentistry, MGM Medical College and Hospital, Jamshedpur, Jharkhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Palak Jain","family":"Choudhary","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine and Radiology, People\u2019s College of Dental Sciences and Research Centre, Bhopal, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akshay K.","family":"Agarwal","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine and Radiology, People\u2019s College of Dental Sciences and Research Centre, Bhopal, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aparna","family":"Raj","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine and Radiology, People\u2019s College of Dental Sciences and Research Centre, Bhopal, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,12,17]]},"reference":[{"issue":"5","key":"R1-20251218","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1111\/j.1834-7819.1996.tb03136.x","article-title":"Oral submucous fibrosis: A review","volume":"41","author":"Cox","year":"1996","journal-title":"Aust Dent J"},{"key":"R2-20251218","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1016\/0030-4220(66)90367-7","article-title":"Oral submucous fibrosis","volume":"22","author":"Pindborg","year":"1966","journal-title":"Oral Surg Oral Med Oral 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Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_1426_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:46:48Z","timestamp":1787068008000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_1426_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":8,"journal-issue":{"issue":"Suppl 4","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/jpbs.jpbs_1426_25","relation":{},"ISSN":["0976-4879","0975-7406"],"issn-type":[{"value":"0976-4879","type":"print"},{"value":"0975-7406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"2025-08-08","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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