{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:39:45Z","timestamp":1787071185232,"version":"build-2736575974"},"reference-count":15,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>The purpose of this case-control study was to evaluate the role of TNF-\u03b1 in gingival crevicular fluid among obese women with chronic periodontitis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>A total of 60 subjects were randomly selected for the study. The study population was further divided into three groups (Group 1, Obese women without periodontitis; Group 2, Non-obese women without periodontitis; Group 3, Obese with chronic periodontitis). Gingival crevicular fluid samples were taken for assessment based on clinical parameters like probing depth, bleeding on probing, and BMI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>There was significant increase in the level of TNF-\u03b1 in gingival crevicular fluid from obese patients with chronic periodontitis and a positive correlation was found between TNF-\u03b1 levels and values of the plaque index, OHI \u2013I and BMI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Based on these results, it can be concluded that GCF level of TNF-\u03b1 was significantly higher in obese patients with and without chronic periodontitis, and highest in obese patients with chronic periodontitis group.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jpbs.jpbs_145_22","type":"journal-article","created":{"date-parts":[[2022,7,13]],"date-time":"2022-07-13T15:05:34Z","timestamp":1657724734000},"page":"S765-S768","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Evaluation of Level of TNF-\u03b1 among Obese Patients with and without Chronic Periodontitis"],"prefix":"10.4103","volume":"14","author":[{"given":"Kamal Hameed","family":"Fathima","sequence":"first","affiliation":[{"name":"Associate Professor, Department of Dentistry, Srimuthukumaran Medical College and Research Institute, Mangadu, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Venkateshwaran","family":"Rajendran","sequence":"additional","affiliation":[{"name":"Reader, Department of Prosthodontics, Asan Memorial Dental College and Hospital, Keerapakkam, Chengalpattu, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prasanna","family":"Sekhar","sequence":"additional","affiliation":[{"name":"Reader, Department of Oral Pathology, Seema Dental College and Hospital, Rishikesh, Uttarakhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harish Vadivelu","family":"Sivasubramaniam","sequence":"additional","affiliation":[{"name":"Prosthodontist, General Practitioner, Annanager, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2022,7,13]]},"reference":[{"key":"R1-20250925","doi-asserted-by":"crossref","first-page":"3765","DOI":"10.1210\/en.2003-0580","article-title":"Minireview: The adipocyte--at the crossroads of energy homeostasis, inflammation, and atherosclerosis","volume":"144","author":"Rajala","year":"2003","journal-title":"Endocrinology"},{"key":"R2-20250925","doi-asserted-by":"crossref","first-page":"3666","DOI":"10.1073\/pnas.72.9.3666","article-title":"An endotoxin-induced serum factor that causes necrosis of tumor","volume":"72","author":"Carswell","year":"1975","journal-title":"Proc Natl Acad Sci USA"},{"key":"R3-20250925","doi-asserted-by":"crossref","first-page":"7","DOI":"10.14219\/jada.archive.1964.0034","article-title":"The simplified oral hygiene index","volume":"68","author":"Greene","year":"1964","journal-title":"J Am Dent Assoc"},{"key":"R4-20250925","doi-asserted-by":"crossref","first-page":"121","DOI":"10.3109\/00016356408993968","article-title":"Periodontal disease in pregnancy. 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