{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T15:58:53Z","timestamp":1792166333416,"version":"4.4.0"},"reference-count":8,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 4","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,12]]},"abstract":"\n Background:<\/jats:title>\n The rising popularity of e-cigarettes among Indian youth raises concerns about potential oral health consequences, particularly mucosal lesions. Limited data exist on this association in the Indian context.<\/jats:p>\n <\/jats:sec>\n \n Objectives:<\/jats:title>\n To assess the prevalence of oral lesions among young e-cigarette users and examine usage patterns and risk awareness.<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods:<\/jats:title>\n This is a cross-sectional study of 300 urban Indians (150 users, 150 nonusers) aged 18\u201335 years. Participants underwent standardized oral examinations and completed structured questionnaires. Statistical analyses included prevalence ratios (Poisson regression) and Chi-square tests.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n E-cigarette users showed significantly higher prevalence of leukoplakia (9.3% vs. 3.3%, relative risk [RR] = 2.80,\n P<\/jats:italic>\n = 0.038) and oral ulcers (8.0% vs. 2.7%, RR = 3.00,\n P<\/jats:italic>\n = 0.045), daily users had 2.1 \u00d7 higher lesion risk (95% confidence interval [CI]: 1.25\u20133.52,\n P<\/jats:italic>\n = 0.005), and only 15.3% of users recognized oral health risks versus 28.7% of nonusers (\n P<\/jats:italic>\n = 0.008).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n E-cigarette use was independently associated with oral lesions, demonstrating clear dose\u2013response relationships. Critical knowledge gaps exist regarding vaping risks, underscoring the need for targeted public health interventions<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/jpbs.jpbs_1505_25","type":"journal-article","created":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T08:03:02Z","timestamp":1766044982000},"page":"S3410-S3412","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Vaping Troubles: Exploring the Link Between E-Cigarettes and Oral Lesions in India\u2019s Urban Youth"],"prefix":"10.4103","volume":"17","author":[{"given":"Gowrishankar","family":"Sekar","sequence":"first","affiliation":[{"name":"Department of Oral Medicine and Radiology, Chettinad Dental College and Research Institute, Chengalpet, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pratheeth","family":"Gundlapalle","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine and Radiology, C.K.S Theja Institute of Dental Sciences, Tirupati, Andhra Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Senthilkumar","family":"Elango","sequence":"additional","affiliation":[{"name":"Department of Public Health Dentistry, Chettinad Dental College and Research Institute, Chengalpet, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sangamithra","family":"Surendran","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Pathology, Chettinad Dental College and Research Institute, Chengalpet, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Anitha","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics, RVS Dental College and Hospital, Coimbatore, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K A","family":"Acchuthakrishnan","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Chettinad Dental College and Research Institute, Chengalpet, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nagappan","family":"Nagappan","sequence":"additional","affiliation":[{"name":"Department of Public Health Dentistry, Chettinad Dental College and Research Institute, Chengalpet, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,12,17]]},"reference":[{"key":"R1-20251218","first-page":"e571","article-title":"Electronic cigarettes: A policy statement from the American Heart Association","volume":"140","author":"Bhatnagar","year":"2019","journal-title":"Circulation"},{"key":"R2-20251218","first-page":"943","article-title":"Recent updates on electronic cigarette aerosol and inhaled nicotine effects on periodontal and pulmonary tissues","volume":"26","author":"Javed","year":"2020","journal-title":"Oral Dis"},{"key":"R3-20251218","first-page":"539","article-title":"Smokeless tobacco and public health in India","volume":"151","author":"Gupta","year":"2020","journal-title":"Indian J Med Res"},{"key":"R4-20251218","first-page":"110","article-title":"An overview of the tobacco problem in India","volume":"42","author":"Mishra","year":"2021","journal-title":"Indian J Med Paediatr Oncol"},{"key":"R6-20251218","first-page":"245","article-title":"E-cigarettes in India: Prevalence, patterns, and policy implications","volume":"27","author":"Yadav","year":"2022","journal-title":"J Subst Use"},{"key":"R7-20251218","first-page":"5108","article-title":"E-cigarette vapor induces an apoptotic response in human gingival epithelial cells through the caspase-3 pathway","volume":"236","author":"Rouabhia","year":"2021","journal-title":"J Cell Physiol"},{"key":"R8-20251218","first-page":"1335","article-title":"Modifications in human oral fibroblast ultrastructure, collagen production, and lysosomal compartment after electronic cigarette aerosol exposure","volume":"35","author":"Sancilio","year":"2020","journal-title":"Histol Histopathol"},{"key":"R9-20251218","first-page":"193","article-title":"Counterfeit electronic cigarette products with mislabeled nicotine concentrations","volume":"8","author":"Omaiye","year":"2022","journal-title":"Tob Regul Sci"}],"container-title":["Journal of Pharmacy and Bioallied Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_1505_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:46:52Z","timestamp":1787068012000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_1505_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":8,"journal-issue":{"issue":"Suppl 4","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/jpbs.jpbs_1505_25","relation":{},"ISSN":["0976-4879","0975-7406"],"issn-type":[{"value":"0976-4879","type":"print"},{"value":"0975-7406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"2025-08-28","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-13","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}