{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T20:22:14Z","timestamp":1787775734041,"version":"build-2784847793"},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 1","license":[{"start":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T00:00:00Z","timestamp":1768176000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,2]]},"abstract":"\n Aim:<\/jats:title>\n To compare the impact of early orthodontic treatment to an untreated control group in order to assess how it affects pediatric patients\u2019 craniofacial development and dental relationships.<\/jats:p>\n <\/jats:sec>\n \n Methodology:<\/jats:title>\n Twelve children between the ages of 8 and 10 years participated in the intervention group and an untreated control group in this 36-month follow-up study. Both the baseline and final evaluations included thorough cephalometric, dental, and soft tissue evaluations.<\/jats:p>\n <\/jats:sec>\n \n Result:<\/jats:title>\n \n Sagittal jaw relationships, maxillary transverse width, overjet and overbite reduction, facial convexity, and lip competence all significantly improved in the intervention group. There were not many changes in the control group. Significant intergroup differences were confirmed by statistical analysis (\n P<\/jats:italic>\n < 0.05).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n By improving occlusal harmony, improving facial aesthetics, and positively influencing craniofacial growth, early orthodontic treatment during the mixed dentition stage may lessen the need for more involved future interventions.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/jpbs.jpbs_1509_25","type":"journal-article","created":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T14:02:15Z","timestamp":1768226535000},"page":"S188-S190","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Evaluating the Impact of Early Orthodontic Intervention on Pediatric Craniofacial Development: A Longitudinal Study"],"prefix":"10.4103","volume":"18","author":[{"given":"Vijender","family":"Kumar","sequence":"first","affiliation":[{"name":"Department of Orthodontics and Dentofacial Orthopedics, MM College of Dental Sciences and Research, Ambala, Haryana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danish U. Z.","family":"Khan","sequence":"additional","affiliation":[{"name":"Department of Dentistry, Era\u2019s Lucknow Medical College and Hospital, Lucknow, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shweta N.","family":"Lakra","sequence":"additional","affiliation":[{"name":"Department of Orthodontics and Dentofacial Orthopedics, Hazaribag College of Dental Sciences and Hospital, Hazaribag, Jharkhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lincy R.","family":"Thomas","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, Faculty of Dentistry, AIMST University, Bedong, Kedah, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohit","family":"Zarekar","sequence":"additional","affiliation":[{"name":"Department of Pedodontics and Preventive Dentistry, Zarekar\u2019s Pediatric and Family Multi-Speciality Dental Clinic, Ahilyanagar, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Najmul","family":"Huda","sequence":"additional","affiliation":[{"name":"Department of Orthodontics and Dentofacial Orthopedics, Infinite Smiles Multispecialty Dentistry, Hyderabad, Telangana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miral","family":"Mehta","sequence":"additional","affiliation":[{"name":"Department of Pedodontics and Preventive Dentistry, Karnavati School of Dentistry, Karnavati University, Gandhinagar, Gujarat, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,1,12]]},"reference":[{"key":"R1-20260310","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1067\/mod.2000.105571","article-title":"Treatment timing for Twin-block therapy","volume":"118","author":"Baccetti","year":"2000","journal-title":"Am J Orthod Dentofacial 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malocclusion) in children and adolescents","volume":"3","author":"Batista","year":"2018","journal-title":"Cochrane Database Syst Rev"},{"key":"R6-20260310","doi-asserted-by":"crossref","first-page":"e22spe2","DOI":"10.1590\/2177-6709.27.2.e22spe2","article-title":"Very early orthodontic treatment: When, why and how?","volume":"27","author":"Schneider-Moser","year":"2022","journal-title":"Dental Press J Orthod"},{"key":"R7-20260310","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1111\/adj.12474","article-title":"Timing orthodontic treatment: Early or late?","volume":"62","author":"Fleming","year":"2017","journal-title":"Aust Dent J"},{"key":"R8-20260310","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.14219\/jada.archive.2000.0043","article-title":"Early vs. late orthodontic treatment","volume":"131","author":"Solomon","year":"2000","journal-title":"J Am Dent 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