{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:26:50Z","timestamp":1787840810125,"version":"build-2784847793"},"reference-count":22,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 5","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:p>This report highlights a rare occurrence of inferior alveolar nerve (IAN) injury resulting from calcium hydroxide extrusion during endodontic treatment. The patient experienced severe pain and paresthesia in the lower right lip following root canal treatment due to the inadvertent overflow of calcium hydroxide into the IAN canal. No surgical intervention was performed, and the patient received non-steroidal anti-inflammatory analgesics and vitamin B complex injections to manage the symptoms. At 6 months, complete resorption of the root canal material occurred, resulting in further reduction in paresthesia. After a 2-year follow-up, the complete disappearance of paresthesia occurred. The importance of the preoperative radiographs is highlighted. The lack of radiographic assessment at the patient\u2019s request led to calcium hydroxide overflow.<\/jats:p>","DOI":"10.4103\/jpbs.jpbs_160_24","type":"journal-article","created":{"date-parts":[[2025,1,30]],"date-time":"2025-01-30T11:06:37Z","timestamp":1738235197000},"page":"S4900-S4904","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Diagnosis and Management of Inferior Alveolar Nerve Injury Caused by Calcium Hydroxide Extrusion during Root Canal Treatment: Case Report"],"prefix":"10.4103","volume":"16","author":[{"given":"Manal","family":"Almaslamani","sequence":"first","affiliation":[{"name":"Department of Clinical Sciences, College of Dentistry, Ajman University, Centre of Medical and Bio-Allied Health Sciences Research, Ajman, Unite Arab Emirates"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suliman","family":"Alhassawi","sequence":"additional","affiliation":[{"name":"General Practitioner, Private Clinic, Kuwait City, Kuwait"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prathibha","family":"Prasad","sequence":"additional","affiliation":[{"name":"Department of Basic Dental Sciences, College of Dentistry, Ajman University, Centre of Medical and Bio-Allied Health Sciences Research, Ajman, Unite Arab Emirates"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maher","family":"Alshayeb","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, College of Dentistry, Ajman University, Centre of Medical and Bio-Allied Health Sciences Research, Ajman, Unite Arab Emirates"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,1,30]]},"reference":[{"key":"R1-20250130","doi-asserted-by":"crossref","first-page":"1291","DOI":"10.1016\/j.joen.2008.07.028","article-title":"Clinical implications and microbiology of bacterial persistence after treatment procedures","volume":"34","author":"Siqueira","year":"2008","journal-title":"J Endod"},{"key":"R2-20250130","first-page":"3","article-title":"Antimicrobial and chemical study of MTA, portland cement, calcium hydroxide paste, sealapex and dycal","volume":"11","author":"Estrela","year":"2000","journal-title":"Braz Dent J"},{"key":"R3-20250130","first-page":"c57","article-title":"Loss of sight caused by calcium hydroxide paste accidentally splashed into the eye during endodontic treatment:Case report","volume":"78","author":"Lipski","year":"2012","journal-title":"J Can Dent Assoc"},{"key":"R4-20250130","first-page":"1134","article-title":"Inferior alveolar nerve injury due to the extrusion of calcium hydroxide during endodontic treatment:A case report","volume":"48","author":"Kasapo\u011flu","year":"2022","journal-title":"J Endod"},{"key":"R5-20250130","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1111\/j.1365-2591.2010.01816.x","article-title":"Differential diagnosis of endodontic-related inferior alveolar nerve paraesthesia with cone beam computed tomography:A case report","volume":"44","author":"Gambarini","year":"2011","journal-title":"Int Endod J"},{"key":"R6-20250130","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1111\/aej.12382","article-title":"Massive extrusion of calcium hydroxide paste containing barium sulphate during endodontic treatment","volume":"46","author":"Fons\u00eaca","year":"2020","journal-title":"Aust Endod J"},{"key":"R7-20250130","first-page":"e43","article-title":"Inferior Alveolar nerve injury resulting from overextension of calcium hydroxide:A case report","volume":"70","author":"Lee","year":"2012","journal-title":"J Oral Maxillofac Surg"},{"key":"R8-20250130","first-page":"e54","article-title":"Neurological complications after endodontic treatment:A case series","volume":"104","author":"Liou","year":"2007","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"R9-20250130","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1016\/j.jcms.2013.11.007","article-title":"A systematic case review and report of two cases","volume":"42","author":"Olsen","year":"2014","journal-title":"J Craniomaxillofac Surg"},{"key":"R10-20250130","first-page":"102","article-title":"Overextension of nonsetting calcium hydroxide in endodontic treatment:Literature review and case report","volume":"7","author":"Shahravan","year":"2012","journal-title":"Iran Endod J"},{"key":"R11-20250130","doi-asserted-by":"crossref","first-page":"1460","DOI":"10.1016\/j.joen.2011.06.016","article-title":"Endodontic-related paresthesia:A case report and literature review","volume":"37","author":"Ahonen","year":"2011","journal-title":"J Endod"},{"key":"R12-20250130","first-page":"894","article-title":"Assessment of iatrogenic nerve injuries in relation to root canal therapy:A clinical study","volume":"36","author":"Zhang","year":"2010","journal-title":"J Endod"},{"key":"R13-20250130","first-page":"680","article-title":"Lingual paresthesia and pain following root canal treatment of mandibular molars with long roots:A case report","volume":"47","author":"Durval","year":"2021","journal-title":"J Endod"},{"key":"R14-20250130","first-page":"671","article-title":"Severe mandibular nerve injury caused by endodontic treatment:Case report and review of the literature","volume":"68","author":"de Figueiredo","year":"2010","journal-title":"J Oral Maxillofac Surg"},{"key":"R15-20250130","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1046\/j.1365-2591.2000.00269.x","article-title":"Necrosis of the gingiva caused by calcium hydroxide:A case report","volume":"33","author":"De Bruyne","year":"2000","journal-title":"Int Endod J"},{"key":"R16-20250130","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1016\/j.tripleo.2007.11.026","article-title":"Severe tissue necrosis following intra-arterial injection of endodontic calcium hydroxide:A case series","volume":"105","author":"Sharma","year":"2008","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"R19-20250130","first-page":"646","article-title":"Management of extruded calcium hydroxide in endodontic therapy:A systematic review","volume":"45","author":"Ahmad","year":"2019","journal-title":"J Endod"},{"key":"R20-20250130","doi-asserted-by":"crossref","first-page":"1757","DOI":"10.1016\/j.joen.2010.08.007","article-title":"Outcome of endodontic surgery:a meta-analysis of the literature-- part 1:Comparison of traditional root-end surgery and endodontic microsurgery","volume":"36","author":"Setzer","year":"2010","journal-title":"J Endod"},{"key":"R21-20250130","first-page":"e84","article-title":"Patient dose evaluation in intraoral radiography using film, photostimulable phosphor, and digital detectors","volume":"131","author":"Serafetinides","year":"2021","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"R22-20250130","first-page":"1","article-title":"Comparative evaluation of effective dose and image quality of different dental imaging modalities in pediatric patients:A systematic review","volume":"45","author":"Swetha","year":"2021","journal-title":"J Clin Pediatr Dent"},{"key":"R24-20250130"},{"key":"R25-20250130","first-page":"146","article-title":"Clinical recommendations regarding use of dental cone beam computed tomography in oral and maxillofacial radiology:Position statement","volume":"133","year":"2022","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol"}],"container-title":["Journal of Pharmacy and Bioallied Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_160_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T13:29:25Z","timestamp":1787837365000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_160_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":22,"journal-issue":{"issue":"Suppl 5","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/jpbs.jpbs_160_24","relation":{},"ISSN":["0976-4879","0975-7406"],"issn-type":[{"value":"0976-4879","type":"print"},{"value":"0975-7406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"2024-03-03","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-07-12","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}