{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:25:26Z","timestamp":1787772326947,"version":"build-2784847793"},"reference-count":24,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 1","license":[{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>The study aims to explore the gut flora presentation among Type 1 DM children with and without metabolic risks (MR) at a tertiary care center.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>A cross-sectional, observational study was conducted on children with T1DM (n = 68, mean-age = 12.9 years, disease-duration = 5.5 years, average HbA1c = 9.8%) divided into two groups based on with (n = 35) and without (n = 33) metabolic risk factors. Clinical-history, anthropometry, biochemical investigations, and body composition analysis was performed. Stool samples were collected; DNA extraction and targeted 16srRNA gene amplicon sequencing was performed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Significant differences were observed in the relative abundance of gut microbiome at the family and genera level in children with metabolic risk as compared to without metabolic risk.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Gut microbiome significantly differs in children with or without MR among T1DM cases.<\/jats:p>\n                  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