{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:21:40Z","timestamp":1787840500857,"version":"build-2784847793"},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 2","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:p>Ovarian carcinosarcoma (MMMT\u2014malignant mixed M\u00fcllerian tumors) is highly aggressive, rare tumor, affecting postmenopausal women with the incidence peak in the sixth decade with significant morbidity and mortality. Uterine carcinosarcomas are rare tumors comprising less than 5% of uterine malignancies. Ovarian cancer is the seventh cause of death and morbidity in females worldwide.To study about the clinical, morphological, and immunohistochemical study of case series of ovarian and uterine carcinosarcoma. Retrospective study of three cases. In first case a 50-year-old woman presented with a left ovarian tumor with a clinical diagnosis of carcinoma of ovary, USG-malignant ovarian tumor. Cancer antigen-125 (Ca-125) was elevated. She underwent surgery and final diagnosis was ovarian carcinosarcoma with high-grade papillary serous carcinoma of endometrium. In second case a 56-year-old woman presented with mass descending per vaginum\u2014three years, abdominal pain\u2014three months. Clinical diagnosis of malignant tumor of the right ovary was made. Ca-125 was elevated. She underwent surgery and the final diagnosis was right ovarian carcinosarcoma with a heterologous component and omental metastatic deposit. In third case a 48-year-old woman presented with continuous bleeding per vaginum for two months. Diagnosed as abnormal uterine bleeding\u2014 leiomyoma. She underwent panhysterectomy with lymph nodes removal and final diagnosis was uterine carcinosarcoma. Ovarian carcinosarcomas are very aggressive tumors that are usually diagnosed at an advanced stage due to its asymptomatic nature, its lack of active screening, and early detection techniques. The survival rate after diagnosis varies by stage of disease and uterine and ovarian carcinosarcomas.er horizons involving younger patients with asymptomatic severe AS, and long term outcomes of valve durability and moderate AS in combination with cardiac failure bicuspid aortic valve stenosis and pure native aortic regurgitation are however still under research.<\/jats:p>","DOI":"10.4103\/jpbs.jpbs_1658_24","type":"journal-article","created":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T01:03:39Z","timestamp":1750208619000},"page":"S2021-S2024","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Carcinosarcoma of Uterus and Ovary\u2014Clinical, Morphological, and Immunohistochemical Study of Case Series"],"prefix":"10.4103","volume":"17","author":[{"given":"Thamilselvi","family":"Ramachandran","sequence":"first","affiliation":[{"name":"Department of Pathology, Vinayaka Mission\u2019s Kirupananda Variyar Medical College and Hospital, Vinayaka Mission\u2019s Research Foundation (DU), Salem, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anbu Lenin","family":"Kulandaivel","sequence":"additional","affiliation":[{"name":"Department of Transfusion Medicine, Vinayaka Mission\u2019s Kirupananda Variyar Medical College and Hospital, Vinayaka Mission\u2019s Research Foundation (DU), Salem, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Poovizhi","family":"Inbasekaran","sequence":"additional","affiliation":[{"name":"Department of Pathology, Vinayaka Mission\u2019s Kirupananda Variyar Medical College and Hospital, Vinayaka Mission\u2019s Research Foundation (DU), Salem, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jayamani","family":"Baskaran","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Vinayaka Mission\u2019s Kirupananda Variyar Medical 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carcinosarcomas and grade 3 endometrioid cancers: Evidence for distinct tumor behavior","volume":"112","author":"Bansal","year":"2008","journal-title":"Obstet Gynecol"},{"key":"R7-20250618","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1016\/j.ygyno.2007.08.060","article-title":"Serum CA 125 predicts extrauterine disease and survival MH in uterine carcinosarcoma","volume":"107","author":"Huang","year":"2007","journal-title":"Gynecol Oncol"},{"key":"R8-20250618","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1159\/000494335","article-title":"Uterine carcinosarcomas-diagnosis and management","volume":"41","author":"Denschlag","year":"2018","journal-title":"Oncol Res Treat"},{"key":"R9-20250618","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1016\/S0360-3016(03)01561-X","article-title":"Malignant mixed mullerian tumors of the uterus: Analysis of patterns of failure, prognostic factors and treatment outcome","volume":"58","author":"Callister","year":"2004","journal-title":"Int J Radiat Oncol Biol Phys"}],"container-title":["Journal of Pharmacy and Bioallied Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_1658_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T13:24:01Z","timestamp":1787837041000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_1658_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":9,"journal-issue":{"issue":"Suppl 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