{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T20:34:25Z","timestamp":1786739665088,"version":"build-2736575974"},"reference-count":8,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 1","license":[{"start":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T00:00:00Z","timestamp":1769644800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,2]]},"abstract":"\n Objectives:<\/jats:title>\n Ethmoidal air cell variants such as Agger nasi, Haller, Onodi, uncinate, and ethmoid bullae are critical anatomical structures influencing the outcomes of functional endoscopic sinus surgery (FESS). This study evaluated their prevalence and gender-specific distribution in a Sangli, Maharashtra, India, via cone beam computed tomography (CBCT).<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods:<\/jats:title>\n \n A cross-sectional retrospective analysis of 258 CBCT scans (150 males, 108 females; ages 18\u201365) was conducted. The presence of five defined ethmoidal variations was recorded (absent\/unilateral\/bilateral). Two radiologists independently assessed images; disagreements were resolved by consensus. Statistical significance in gender distribution was tested via the Chi-square test (\n P<\/jats:italic>\n < 0.05 considered significant).\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n Onodi cells were observed in 96 cases (32%), Haller in 53 (17.7%), Agger nasi in 31 (10.3%), uncinate bulla in 8 (2.7%), and prominent ethmoid bulla in 5 (1.7%). Gender distribution showed male predominance in all variants except uncinate bulla, but none achieved statistical significance (\n P<\/jats:italic>\n > 0.05).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions:<\/jats:title>\n Onodi and Haller cells exhibit high prevalence, emphasizing the necessity for thorough pre-FESS CBCT evaluation. Despite non-significant gender differences, these variations should be carefully assessed in individual patients. The findings support the role of personalized radiological analysis to reduce surgical risks.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/jpbs.jpbs_1662_25","type":"journal-article","created":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T13:02:31Z","timestamp":1769778151000},"page":"S197-S199","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Quantitative Assessment of Ethmoidal Air Cell Variations by Age and Gender Using Cone-Bone Computed Tomography"],"prefix":"10.4103","volume":"18","author":[{"given":"Manishkumar Dinkar","family":"Shete","sequence":"first","affiliation":[{"name":"Department of Oral Medicine and Radiology, Vasantdada Patil Dental College and Hospital, Sangli, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vela D.","family":"Desai","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine and Radiology, Jaipur Dental College, Jaipur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dipak Baliram","family":"Patil","sequence":"additional","affiliation":[{"name":"Department of Dentistry, BKL Walawalkar Rural Medical College and Hospital, Chiplun, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Almas Rafiahamad","family":"Patel","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine and Radiology, M A Rangoonwala College of Dental Science and Research Center, Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aditya S.","family":"Dupare","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine and Radiology, Yogita Dental College and Hospital, Khed, Ratnagiri, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leena Rahul","family":"Salunkhe","sequence":"additional","affiliation":[{"name":"Department of Community Medicine, Dr. D. Y. Patil Medical College, Kolhapur, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,1,29]]},"reference":[{"key":"R1-20260310","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/j.nic.2022.01.008","article-title":"Normal anatomic structures and variants of the sinonasal cavities, orbit, and jaw","volume":"32","author":"Moonis","year":"2022","journal-title":"Neuroimaging Clin N Am"},{"key":"R2-20260310","first-page":"e82506","article-title":"Clinical and radiological significance of anatomical variations in paranasal sinuses: A retrospective CT-based study","volume":"17","author":"Subbiah","year":"2025","journal-title":"Cureus"},{"key":"R3-20260310","doi-asserted-by":"crossref","first-page":"110","DOI":"10.5001\/omj.2014.27","article-title":"Clinically significant anatomical variants of the paranasal sinuses","volume":"29","author":"Al-Abri","year":"2014","journal-title":"Oman Med J"},{"key":"R4-20260310","doi-asserted-by":"crossref","first-page":"1324","DOI":"10.11607\/jomi.5854","article-title":"Evaluating maxillary sinus septa using cone beam computed tomography: Is there a difference in frequency and type between the dentate and edentulous posterior maxilla?","volume":"32","author":"Schriber","year":"2017","journal-title":"Int J Oral Maxillofac Implants"},{"key":"R5-20260310","doi-asserted-by":"crossref","first-page":"371","DOI":"10.4103\/jips.jips_113_20","article-title":"Anatomic variations of the osteomeatal complex and its relationship to patency of the maxillary ostium: A retrospective evaluation of cone-beam computed tomography and its implications for sinus augmentation","volume":"20","author":"Sandhu","year":"2020","journal-title":"J Indian Prosthodont Soc"},{"key":"R6-20260310","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1288\/00005537-199101000-00010","article-title":"Paranasal sinus bony anatomic variations and mucosal abnormalities: CT analysis for endoscopic sinus surgery","volume":"101","author":"Bolger","year":"1991","journal-title":"Laryngoscope"},{"issue":"Suppl 3","key":"R7-20260310","doi-asserted-by":"crossref","first-page":"2231","DOI":"10.1007\/s12070-019-01716-9","article-title":"Anatomical variations of the nose and paranasal sinuses: A computed tomographic study","volume":"71","author":"Devaraja","year":"2019","journal-title":"Indian J Otolaryngol Head Neck Surg"},{"key":"R8-20260310","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1046\/j.1469-7580.2000.19720221.x","article-title":"Anatomical variations in the human paranasal sinus region studied by CT","volume":"197","author":"Perez-Pinas","year":"2000","journal-title":"The Journal of Anatomy."}],"container-title":["Journal of Pharmacy and Bioallied Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_1662_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T19:30:56Z","timestamp":1786735856000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_1662_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,29]]},"references-count":8,"journal-issue":{"issue":"Suppl 1","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/jpbs.jpbs_1662_25","relation":{},"ISSN":["0976-4879","0975-7406"],"issn-type":[{"value":"0976-4879","type":"print"},{"value":"0975-7406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,29]]},"assertion":[{"value":"2025-10-13","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-26","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}