{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T19:59:20Z","timestamp":1790279960655,"version":"4.1.0"},"reference-count":11,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,10]]},"abstract":"\n A\n BSTRACT<\/jats:sc>\n <\/jats:title>\n \n Objectives:<\/jats:title>\n This study aimed to assess the prevalence of psychiatric comorbidities among hemodialysis patients along with their impact on QOL.<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods:<\/jats:title>\n \n An observational cross-sectional study was conducted on 96 patients undergoing hemodialysis for at least three months. Assessments included Psychiatric History taking proforma, Hamilton Depression Rating Scale (HAM-D), Hamilton Anxiety Rating Scale (HAM-A), Modified Kuppuswamy Scale, and WHOQOL-BREF. Data were analyzed using SPSS v25, with\n P<\/jats:italic>\n < 0.05 considered statistically significant.\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n Psychiatric comorbidities were present in 62 (64.58%) cases, with both anxiety and depression being present in 29 (46.77%) patients. Compared to those without psychiatric comorbidities, patients with psychiatric comorbidities had significantly lower total median score (47 vs. 71), scores in the physical domain (46 vs. 64), psychological domain (46 vs. 79), social domain (58 vs. 75), and the environmental domain (38 vs. 66) (\n P<\/jats:italic>\n < 0.0001 for all). HAM-D and HAM-A scores showed a strong positive correlation between themselves (\u03c1 = 0.522,\n P<\/jats:italic>\n < 0.0001) and strong negative correlations with all WHO QOL domains, including physical, psychological, social, and environmental scores (\u03c1 ranging from \u20130.702 to \u20130.811, all\n P<\/jats:italic>\n < 0.0001).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Psychiatric comorbidities, particularly depression and anxiety, were highly prevalent in chronic kidney disease patients undergoing hemodialysis and had a profound negative impact on their quality of life.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/jpbs.jpbs_1679_25","type":"journal-article","created":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T17:00:12Z","timestamp":1766422812000},"page":"223-226","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Quality of Life and Psychiatric Comorbidities in CKD Patients on Hemodialysis"],"prefix":"10.4103","volume":"17","author":[{"given":"Jivitesh Singh","family":"Chahal","sequence":"first","affiliation":[{"name":"Department of Psychiatry, Guru Gobind Singh Medical College and Hospital, Faridkot, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pir Dutt","family":"Bansal","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Guru Gobind Singh Medical College and Hospital, Faridkot, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aman","family":"Bharti","sequence":"additional","affiliation":[{"name":"Department of Medicine, Guru Gobind Singh Medical College and Hospital, Faridkot, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bhavneesh","family":"Saini","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Guru Gobind Singh Medical College and Hospital, Faridkot, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sumit","family":"Saini","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Guru Gobind Singh Medical College and Hospital, Faridkot, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jivesh","family":"Arora","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Guru Gobind Singh Medical College and Hospital, Faridkot, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramandeep","family":"Kaur","sequence":"additional","affiliation":[{"name":"Department of Computer Applications, Gulzar Group of Institutes, Khanna, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Navjot","family":"Sandhu","sequence":"additional","affiliation":[{"name":"SPM Department, Guru Gobind Singh Medical College and Hospital, Faridkot, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,12,22]]},"reference":[{"key":"R1-20251223","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1186\/s12882-023-03056-x","article-title":"Prevalence and incidence of chronic kidney disease stage 3-5-results from KidDiCo","volume":"24","author":"Kampmann","year":"2023","journal-title":"BMC Nephrol"},{"key":"R2-20251223","doi-asserted-by":"crossref","first-page":"e14420","DOI":"10.1111\/nep.14420","article-title":"Chronic kidney disease prevalence in India: A systematic review and meta-analysis from community-based representative evidence between 2011 to 2023","volume":"30","author":"Talukdar","year":"2025","journal-title":"Nephrology (Carlton)"},{"key":"R3-20251223","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/S0140-6736(16)30448-2","article-title":"Factors affecting outcomes in patients reaching end-stage kidney disease worldwide: Differences in access to renal replacement therapy, modality use, and haemodialysis practices","volume":"388","author":"Robinson","year":"2016","journal-title":"Lancet"},{"key":"R4-20251223","doi-asserted-by":"crossref","first-page":"2132","DOI":"10.1111\/jocn.13904","article-title":"Factors influencing the quality of life of haemodialysis patients according to symptom cluster","volume":"27","author":"Shim","year":"2018","journal-title":"J Clin Nurs"},{"key":"R5-20251223","doi-asserted-by":"crossref","first-page":"296","DOI":"10.33546\/bnj.2080","article-title":"Prevalence of depression in patients with end-stage renal disease undergoing hemodialysis in Saudi Arabia: A cross-sectional study","volume":"8","author":"Sallam","year":"2022","journal-title":"Belitung Nurs J"},{"key":"R6-20251223","doi-asserted-by":"crossref","first-page":"206","DOI":"10.4103\/ipj.ipj_5_18","article-title":"Psychiatric comorbidity in patients undergoing hemodialysis","volume":"27","author":"Goyal","year":"2018","journal-title":"Ind Psychiatry J"},{"key":"R7-20251223","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/s43045-020-0018-3","article-title":"Psychiatric comorbidity and quality of life in patients undergoing hemodialysis","volume":"27","author":"Elhadad","year":"2020","journal-title":"Middle East Curr Psychiatr"},{"key":"R8-20251223","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1186\/s12882-022-03051-8","article-title":"Depression and anxiety symptoms among patients receiving maintenance hemodialysis: A single center cross-sectional study","volume":"23","author":"Ye","year":"2022","journal-title":"BMC Nephrol"},{"key":"R9-20251223","doi-asserted-by":"crossref","first-page":"92","DOI":"10.52403\/ijhsr.20221215","article-title":"Psychiatric comorbidities and their association in patients on dialysis","volume":"12","author":"Verma","year":"2022","journal-title":"Int J Health Sci Res"},{"key":"R10-20251223","doi-asserted-by":"crossref","first-page":"53","DOI":"10.21608\/EJPSY.2024.380498","article-title":"A study of psychiatric comorbidities in a sample of Egyptian patients with end-stage renal disease on hemodialysis","volume":"45","author":"El-Azaba","year":"2024","journal-title":"Egypt J Psychiatry"},{"key":"R11-20251223","doi-asserted-by":"crossref","first-page":"35","DOI":"10.4103\/jesnt.jesnt_24_24","article-title":"Depression, anxiety, and low quality of sleep among Egyptian hemodialysis patients: A single-center study","volume":"25","author":"Abdel","year":"2025","journal-title":"J Egyptian Soc Nephrol Transplant"}],"container-title":["Journal of Pharmacy and Bioallied Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_1679_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T18:54:59Z","timestamp":1786647299000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_1679_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":11,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/jpbs.jpbs_1679_25","relation":{},"ISSN":["0976-4879","0975-7406"],"issn-type":[{"value":"0976-4879","type":"print"},{"value":"0975-7406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10]]},"assertion":[{"value":"2025-10-19","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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