{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:30:42Z","timestamp":1787070642767,"version":"build-2736575974"},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 1","license":[{"start":{"date-parts":[[2025,2,19]],"date-time":"2025-02-19T00:00:00Z","timestamp":1739923200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,5]]},"abstract":"\n A\n BSTRACT<\/jats:sc>\n <\/jats:title>\n \n Introduction:<\/jats:title>\n Cachexia, an involuntary weight loss and wasting of muscle, severely impairs the quality of life and treatment outcomes of survivors after cancer.<\/jats:p>\n <\/jats:sec>\n \n Objectives:<\/jats:title>\n The study opted for this mixed-method design to assess cachexia severity; functional impacts of cachexia; and lived experiences among survivors with the condition.<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n The cross-sectional study carried out at a tertiary care center in Chennai was based on the scores of 60 survivors of cancer, evaluated using the Cachexia Severity Score and Functional Assessment of Anorexia\/Cachexia Therapy Scale, along with semi-structured interviews for six participants.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n The study found a significant negative correlation between cachexia severity and functional ability (\n r<\/jats:italic>\n = \u22120.32,\n P<\/jats:italic>\n = 0.01). Cachexia severity (mean: 81.65) and functional ability (mean: 7.10) indicated significant functional impairment. Qualitative interviews highlighted emotional and physical challenges, with family support and religious beliefs as coping mechanisms, emphasizing the need for holistic care.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Addressing cachexia therefore requires integrating physical rehabilitation, mental health support, and lifestyle adjustments to improve survivors\u2019 quality of life and mitigate its multidimensional impact.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/jpbs.jpbs_1731_24","type":"journal-article","created":{"date-parts":[[2025,2,19]],"date-time":"2025-02-19T09:00:16Z","timestamp":1739955616000},"page":"S658-S660","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Exploring Cachexia: Severity, Functional Abilities, and Personal Experiences of Cancer Survivors through a Mixed-Methods Analysis"],"prefix":"10.4103","volume":"17","author":[{"given":"Deepika","family":"Ramalingam","sequence":"first","affiliation":[{"name":"Department of Child Health Nursing, College of Nursing, Madras Medical College, The Tamil Nadu Dr. M.G.R. Medical University, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theranirajan","family":"Ethiraj","sequence":"additional","affiliation":[{"name":"Dean, College of Nursing, Madras Medical College, The TN Dr. M.G.R. Medical University, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shankar Shanmugam","family":"Rajendran","sequence":"additional","affiliation":[{"name":"Principal, College of Nursing, Madras Medical College, The Tamil Nadu Dr. M.G.R. Medical University, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Duraikannu","family":"Anandhi","sequence":"additional","affiliation":[{"name":"Department of Medical-Surgical Nursing, College of Nursing, Madras Medical College, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Divya","family":"Jayaraman","sequence":"additional","affiliation":[{"name":"Department of Medical-Surgical Nursing, College of Nursing, Madras Medical College, The Tamil Nadu Dr. M.G.R. Medical University, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shabana","family":"Ahamed","sequence":"additional","affiliation":[{"name":"Department of Medical-Surgical Nursing, College of Nursing, Madras Medical College, The Tamil Nadu Dr. M.G.R. Medical University, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Venba","family":"Elangovan","sequence":"additional","affiliation":[{"name":"Department of Medical-Surgical Nursing, College of Nursing, Madras Medical College, The Tamil Nadu Dr. M.G.R. Medical University, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,2,19]]},"reference":[{"key":"R1-20250513","first-page":"5801","article-title":"The impact of exercise on patients with advanced cancer and cachexia:A qualitative study","volume":"30","author":"Bland","year":"2022","journal-title":"Support Care Cancer"},{"key":"R2-20250513","first-page":"502","article-title":"Narrative analysis of interventions for cachexia-affected cancer survivors","volume":"26","author":"Brown","year":"2023","journal-title":"J Palliat Med"},{"key":"R3-20250513","first-page":"789","article-title":"Non-pharmacological interventions for cancer cachexia:A mixed-method study","volume":"24","author":"Buonaccorso","year":"2021","journal-title":"J Palliat Med"},{"key":"R4-20250513","first-page":"97","article-title":"Subjective measures of physical function and quality of life in cancer cachexia:A review","volume":"7","author":"Caeiro","year":"2024","journal-title":"Cancer Rep"},{"key":"R5-20250513","first-page":"2350","article-title":"Correlation of cachexia severity with functional ability in cancer patients","volume":"40","author":"Lee","year":"2021","journal-title":"Clin Nutr"},{"key":"R6-20250513","first-page":"219","article-title":"Semi-structured interviews reveal the profound effects of cachexia on daily activities and emotional states in cancer survivors","volume":"16","author":"Martinez","year":"2022","journal-title":"J Cancer Res Pract"},{"key":"R7-20250513","doi-asserted-by":"crossref","first-page":"101402","DOI":"10.1016\/j.jgo.2022.11.001","article-title":"The prevalence of sarcopenia and cachexia in older patients with localized colorectal cancer","volume":"14","author":"Dolin","year":"2023","journal-title":"J Geriatr Oncol"},{"key":"R8-20250513","first-page":"150","article-title":"Phenomenological exploration of cachexia experiences and their impact on quality of life","volume":"37","author":"Hernandez","year":"2023","journal-title":"Palliat Med"},{"key":"R9-20250513","first-page":"1245","article-title":"Innovative treatment strategies for cancer cachexia:A review","volume":"10","author":"Herremans","year":"2019","journal-title":"J Cachexia Sarcopenia Muscle"}],"container-title":["Journal of Pharmacy and Bioallied Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_1731_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:34:01Z","timestamp":1787067241000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_1731_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,19]]},"references-count":9,"journal-issue":{"issue":"Suppl 1","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/jpbs.jpbs_1731_24","relation":{},"ISSN":["0976-4879","0975-7406"],"issn-type":[{"value":"0976-4879","type":"print"},{"value":"0975-7406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2,19]]},"assertion":[{"value":"2024-11-21","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-12-04","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}