{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:21:41Z","timestamp":1787840501909,"version":"build-2784847793"},"reference-count":7,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 2","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,6]]},"abstract":"\n A\n BSTRACT<\/jats:sc>\n <\/jats:title>\n \n Aim:<\/jats:title>\n The purpose of this study was to compare the microbiological and clinical effects of antimicrobial photodynamic therapy (aPDT) in treating chronic periodontitis by using indocyanine green (ICG) with an 810 nm diode laser and methylene blue (MB) with a 660 nm diode laser as adjuncts to scaling and root planing (SRP).<\/jats:p>\n <\/jats:sec>\n \n Materials and Procedures:<\/jats:title>\n In this split-mouth design research, 14 people were recruited. Three sets of treatment sites were randomly assigned: SRP with aPDT utilizing MB or ICG (test groups) and SRP alone (control group). Using real-time polymerase chain reaction (RT-PCR), samples of subgingival plaque were examined for Tannerella forsythia, Porphyromonas gingivalis, and Treponema denticola. Microbiological counts and clinical indicators, such as Russell\u2019s Periodontal Index (RI), Gingival Index (GI), Plaque Index (PI), clinical attachment loss (CAL), and probing depth (PD), were measured at baseline and three months later.<\/jats:p>\n <\/jats:sec>\n \n Findings:<\/jats:title>\n \n When compared to the control sites, test sites treated with aPDT showed statistically significant improvements in both clinical and microbiological parameters (\n P<\/jats:italic>\n < 0.001).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n MB and ICG photosensitizers combined with antimicrobial photodynamic therapy show great promise as an adjuvant treatment for chronic periodontitis.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/jpbs.jpbs_1823_24","type":"journal-article","created":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T01:02:32Z","timestamp":1750208552000},"page":"S1436-S1438","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Comparative Evaluation of Antimicrobial Photodynamic Therapy Using Methylene Blue (660 nm Diode Laser) and Indocyanine Green (810 nm Diode Laser) in the Management of Chronic Periodontitis: A Clinical and Microbiological Study"],"prefix":"10.4103","volume":"17","author":[{"given":"Saumya","family":"Shankar","sequence":"first","affiliation":[{"name":"Department of Periodontology, Bharati Vidyapeeth (Deemed to be University) Dental College and Hospital, Sangli, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sachin B.","family":"Mangalekar","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Bharati Vidyapeeth (Deemed to be University) Dental College and Hospital, Sangli, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeeth","family":"Rai","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Bharati Vidyapeeth (Deemed to be University) Dental College and Hospital, Sangli, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shashank","family":"Vijapure","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Bharati Vidyapeeth (Deemed to be University) Dental College and Hospital, Sangli, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shruti","family":"Kumbhare","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Bharati Vidyapeeth (Deemed to be University) Dental College and Hospital, Sangli, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prasanna","family":"Sawant","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Bharati Vidyapeeth (Deemed to be University) Dental College and Hospital, Sangli, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,6,18]]},"reference":[{"key":"R1-20250618","doi-asserted-by":"crossref","first-page":"609","DOI":"10.4103\/0970-9290.199598","article-title":"The effect of indocyanine green-mediated photodynamic therapy as an adjunct to scaling and root planing in the treatment of chronic periodontitis:A comparative split-mouth randomized clinical trial","volume":"27","author":"Shingnapurkar","year":"2016","journal-title":"Indian J Dent Res"},{"key":"R2-20250618","doi-asserted-by":"crossref","first-page":"1568","DOI":"10.1902\/jop.2009.090206","article-title":"Short-term effects of photodynamic therapy on periodontal 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