{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:26:33Z","timestamp":1787772393478,"version":"build-2784847793"},"reference-count":11,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:p>\n                    Endometrium scratching is a process of intentionally injuring the endometrium, and after scratching the endometrium, platelet-rich plasma (PRP) is inserted into the endometrial wall to improve pregnancy outcome. This case report revolves around a 33-year-old woman and her 38-year-old husband, who have been married for 3 years and were seeking treatment for their secondary infertility. The female had a history of hypothyroidism, and after the investigation, she was diagnosed with hyperprolactinemia. She also had a history of failure\n                    <jats:italic toggle=\"yes\">in vitro<\/jats:italic>\n                    fertilization (IVF) cycles and two recurrent miscarriages upon investigation. The husband was found to have asthanozoospermia. After diagnosis of the female, we started treatment of cabergoline for hyperprolactinemia, a history of unsuccessful IVF cycles, and two recurrent miscarriages upon investigation. After the treatment of hyperprolactinemia in our clinic, we scheduled ovum pick-up and started the stimulation and performed intra-cytoplasmic sperm injection. After 1 month, we scheduled embryo transfer. On day 1, the progesterone scratched the endometrium wall and loaded the PRP to enhance the endometrial wall, and after an interval of 14 days, we checked the \u03b2-hCG level in the blood, and the result was positive, that is, the level was 1020 mIU\/mL. The successful result of endometrial scratching with PRP improves pregnancy outcomes.\n                  <\/jats:p>","DOI":"10.4103\/jpbs.jpbs_185_24","type":"journal-article","created":{"date-parts":[[2024,5,28]],"date-time":"2024-05-28T01:00:22Z","timestamp":1716858022000},"page":"S2343-S2346","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Effect of Platelet-Rich Plasma (PRP) in Combination with Endometrial Scratching for Patients Undergoing Assisted Reproductive Technology Treatment"],"prefix":"10.4103","volume":"16","author":[{"given":"Krushnali S.","family":"Kadu","sequence":"first","affiliation":[{"name":"Department of Clinical Embryology, School of Allied Health Sciences, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akash","family":"More","sequence":"additional","affiliation":[{"name":"Department of Clinical Embryology, Acharya Vinoba Bhave Rural Hospital, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jarul","family":"Shrivastava","sequence":"additional","affiliation":[{"name":"Department of Clinical Embryology, Acharya Vinoba Bhave Rural Hospital, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gauri","family":"Gajabe","sequence":"additional","affiliation":[{"name":"Department of Clinical Embryology, School of Allied Health Sciences, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prerana","family":"Dagwar","sequence":"additional","affiliation":[{"name":"Department of Clinical Embryology, School of Allied Health Sciences, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Namrata","family":"Chaudhary","sequence":"additional","affiliation":[{"name":"Department of Clinical Embryology, Acharya Vinoba Bhave Rural Hospital, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ritesh","family":"Jadhav","sequence":"additional","affiliation":[{"name":"Department of Clinical Embryology, School of Allied Health Sciences, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,5,29]]},"reference":[{"key":"R1-20240829","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.clinbiochem.2018.03.012","article-title":"Fertility and infertility: Definition and epidemiology","volume":"62","author":"Vander 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overview of current research","volume":"21","author":"G\u00fcnther","year":"2020","journal-title":"J Turk-Ger Gynecol Assoc"},{"key":"R6-20240829","doi-asserted-by":"crossref","first-page":"f6007","DOI":"10.1136\/bmj.f6007","article-title":"Endometrial scratching improves IVF pregnancy rate","volume":"347","author":"Wise","year":"2013","journal-title":"BMJ"},{"key":"R7-20240829","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1007\/s10815-023-02781-4","article-title":"The value of platelet-rich plasma in women with previous implantation failure: A systematic review and meta-analysis","volume":"40","author":"Maged","year":"2023","journal-title":"J Assist Reprod Genet"},{"key":"R8-20240829","doi-asserted-by":"crossref","first-page":"13","DOI":"10.5935\/1518-0557.20210037","article-title":"Autologous platelet-rich plasma optimizes endometrial thickness and pregnancy outcomes in women with refractory thin endometrium of varied aetiology during fresh and frozen-thawed embryo transfer cycles","volume":"26","author":"Dogra","year":"2022","journal-title":"JBRA Assist Reprod"},{"key":"R9-20240829","first-page":"131","article-title":"Hyperprolactinemia, clinical considerations, and infertility in women on antipsychotic medications","volume":"51","author":"Edinoff","year":"2021","journal-title":"Psychopharmacol Bull"},{"key":"R10-20240829","doi-asserted-by":"crossref","first-page":"2672","DOI":"10.1210\/jc.2009-2605","article-title":"Individualized high-dose cabergoline therapy for hyperprolactinemic infertility in women with micro- and macroprolactinomas","volume":"95","author":"Ono","year":"2010","journal-title":"J Clin Endocrinol Metab"},{"key":"R11-20240829","doi-asserted-by":"crossref","first-page":"1659","DOI":"10.1007\/s43032-021-00579-2","article-title":"Use of intra-uterine injection of platelet-rich plasma (PRP) for endometrial receptivity and thickness: A literature review of the mechanisms of action","volume":"28","author":"Mouanness","year":"2021","journal-title":"Reprod Sci"}],"container-title":["Journal of Pharmacy and Bioallied Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_185_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T18:43:00Z","timestamp":1787769780000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_185_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,29]]},"references-count":11,"journal-issue":{"issue":"Suppl 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