{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:21:46Z","timestamp":1787840506095,"version":"build-2784847793"},"reference-count":8,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 2","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,6]]},"abstract":"\n A\n BSTRACT<\/jats:sc>\n <\/jats:title>\n \n Background:<\/jats:title>\n Improving the longevity of restorative materials requires efficient cavity cleaning. It is especially crucial to comprehend how various cavity disinfectants affect the binding strength of restorative materials in primary teeth, where caries advancement happens quickly.<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods:<\/jats:title>\n \n This\n in vitro<\/jats:italic>\n study examined the effects of three cavity disinfectants on the bond strength of restorative materials in primary teeth: 38% silver diamine fluoride (SDF), 5.25% sodium hypochlorite, and 2% chlorhexidine gluconate. Four groups were randomly selected from among 60 removed primary molars with standardized class I cavities: the control group (no disinfectant), the chlorhexidine group, the sodium hypochlorite group, and the SDF group. Composite resin was used to repair cavities after the specified disinfectants were applied. A universal testing equipment was used to assess the bond strength at a crosshead speed of 0.5 mm\/min. ANOVA and post-hoc Tukey\u2019s tests were used for statistical analysis, with significance set at\n \u03b1<\/jats:italic>\n = 0.05.\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n The control group had a mean bond strength (MPa) of 12.5 \u00b1 1.8, followed by the chlorhexidine group (15.3 \u00b1 2.0), the sodium hypochlorite group (14.1 \u00b1 1.7), and the SDF group (9.8 \u00b1 1.5). SDF had the lowest bond strength (\n P<\/jats:italic>\n < 0.01), whereas chlorhexidine had the strongest, far outperforming the control group (\n P<\/jats:italic>\n < 0.01). Additionally, sodium hypochlorite showed a significant improvement over the control group (\n P<\/jats:italic>\n < 0.05).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n When compared to sodium hypochlorite and SDF, chlorhexidine gluconate significantly increased the binding strength of restorative materials in primary teeth. Despite the decreased binding strength, SDF\u2019s antibacterial qualities point to possible therapeutic uses that merit more research. When choosing a cavity disinfectant, one should carefully consider both the product\u2019s antibacterial properties and its impact on bond strength.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/jpbs.jpbs_1880_24","type":"journal-article","created":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T01:03:03Z","timestamp":1750208583000},"page":"S1448-S1450","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["The Effect of Different Cavity Disinfectants on the Bond Strength of Restorative Materials in Primary Teeth"],"prefix":"10.4103","volume":"17","author":[{"given":"Arun Roy","family":"James","sequence":"first","affiliation":[{"name":"Department of Pediatric and Preventive Dentistry, St Gregorios Dental College, Kothamangalam, Ernakulam, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N","family":"Dhanesh","sequence":"additional","affiliation":[{"name":"Department of Pediatric and Preventive Dentistry, St Gregorios Dental College, Kothamangalam, Ernakulam, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eldho","family":"Babu","sequence":"additional","affiliation":[{"name":"Department of Pediatric and Preventive Dentistry, St Gregorios Dental College, Kothamangalam, Ernakulam, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aswathy","family":"Devanandan","sequence":"additional","affiliation":[{"name":"Department of Pediatric and Preventive Dentistry, St Gregorios Dental College, Kothamangalam, Ernakulam, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G Harry","family":"Varghese","sequence":"additional","affiliation":[{"name":"Department of Pediatric and Preventive Dentistry, St Gregorios Dental College, Kothamangalam, Ernakulam, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annie V.","family":"Issac","sequence":"additional","affiliation":[{"name":"Department of Periodontics, St Gregorios Dental College, Chelad, Kothamagalam, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,6,18]]},"reference":[{"key":"R1-20250618","first-page":"215","article-title":"Buonocore memorial lecture. Adhesion to enamel and dentin:Current status and future challenges","volume":"28","author":"Van Meerbeek","year":"2003","journal-title":"Oper Dent"},{"key":"R2-20250618","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1177\/154405910708600115","article-title":"Chlorhexidine preserves dentin bond in vitro","volume":"86","author":"Carrilho","year":"2007","journal-title":"J Dent Res"},{"key":"R3-20250618","first-page":"191","article-title":"Dentin bonding\u2014questions for the new millennium","volume":"2","author":"Perdig\u00e3o","year":"2000","journal-title":"J Adhes Dent"},{"key":"R4-20250618","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/j.dental.2009.11.153","article-title":"Chlorhexidine stabilizes the adhesive interface:A 2-year in vitro study","volume":"26","author":"Breschi","year":"2010","journal-title":"Dent Mater"},{"key":"R5-20250618","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1002\/jemt.23401","article-title":"Effects of sodium hypochlorite as dentin deproteinizing agent and aging media on bond strength of two conventional adhesives","volume":"83","author":"Nima","year":"2020","journal-title":"Microsc Res Tech"},{"key":"R6-20250618","first-page":"128","article-title":"Effect of chlorhexidine on bond strength of two-step etch-and-rinse adhesive systems to dentin of primary and permanent teeth","volume":"23","author":"Ricci","year":"2010","journal-title":"Am J Dent"},{"key":"R7-20250618","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1046\/j.1365-2591.2001.00357.x","article-title":"Effect of sodium hypochlorite on mechanical properties of dentin and tooth surface strain","volume":"34","author":"Sim","year":"2001","journal-title":"Int Endod J"},{"key":"R8-20250618","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1016\/j.jdent.2009.07.004","article-title":"Effect of sodium hypochlorite on dentine mechanical properties. A review","volume":"37","author":"Pascon","year":"2009","journal-title":"J Dent"}],"container-title":["Journal of Pharmacy and Bioallied Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_1880_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T13:24:06Z","timestamp":1787837046000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_1880_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":8,"journal-issue":{"issue":"Suppl 2","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/jpbs.jpbs_1880_24","relation":{},"ISSN":["0976-4879","0975-7406"],"issn-type":[{"value":"0976-4879","type":"print"},{"value":"0975-7406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"2024-12-12","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-23","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}