{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:40:29Z","timestamp":1787071229038,"version":"build-2736575974"},"reference-count":4,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,1]]},"abstract":"\n Background:<\/jats:title>\n Stroke remains a leading cause of disability worldwide, significantly impairing motor function, activities of daily living (ADL), swallowing function, and health-related quality of life (HRQoL). Comprehensive nursing-led interventions may improve these outcomes, yet empirical evidence from controlled trials in Indian hospital settings is limited.<\/jats:p>\n <\/jats:sec>\n \n Aim:<\/jats:title>\n To evaluate the effectiveness of integrated nursing strategies on clinical outcomes and HRQoL among patients with stroke.<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n \n A true experimental pretest\u2013posttest control group design was adopted. Thirty patients with acute stroke admitted to selected hospitals in Salem were randomly assigned to an experimental group (\n n<\/jats:italic>\n = 15) receiving integrated nursing strategies and a control group (\n n<\/jats:italic>\n = 15) receiving routine hospital care. Clinical outcomes assessed included blood pressure and blood sugar control, motor function, ADL, and swallowing function. HRQoL was also evaluated. Statistical analysis involved chi-square tests, paired and independent\n t<\/jats:italic>\n tests.\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n Post-intervention, the experimental group demonstrated statistically significant improvements in blood pressure and blood sugar control (\n P<\/jats:italic>\n < 0.001), motor function (\n P<\/jats:italic>\n < 0.001), ADL (\n P<\/jats:italic>\n < 0.001), swallowing function (\n P<\/jats:italic>\n < 0.001), and HRQoL (\n P<\/jats:italic>\n < 0.001) compared to the control group. No significant differences were observed between groups at baseline.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Integrated nursing strategies were effective in improving both clinical outcomes and HRQoL among patients with stroke. The findings support the feasibility and potential efficacy of structured nursing-led interventions, warranting validation through a large-scale trial.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/jpbs.jpbs_18_26","type":"journal-article","created":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T10:00:25Z","timestamp":1773309625000},"page":"77-79","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Effectiveness of Integrated Nursing Strategies on Clinical Outcomes and Health-Related Quality of Life Among Patients with Stroke: A Pilot Randomized Controlled Study"],"prefix":"10.4103","volume":"18","author":[{"given":"Shalini","family":"Ramasamy","sequence":"first","affiliation":[{"name":"Department of Medical Surgical Nursing, Dhanvantri College of Nursing, Namakkal, Tamil Nadu, India"},{"name":"The Tamil Nadu Dr. M.G.R. Medical University, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Padmavathi","sequence":"additional","affiliation":[{"name":"Dhanvantri College of Nursing, Namakkal, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,3,12]]},"reference":[{"key":"R1-20260416","doi-asserted-by":"crossref","first-page":"175","DOI":"10.4103\/ijmr.IJMR_516_15","article-title":"Incidence and prevalence of stroke in India: A systematic review","volume":"146","author":"Kamalakannan","year":"2017","journal-title":"Indian J Med Res"},{"key":"R2-20260416","doi-asserted-by":"crossref","first-page":"1634","DOI":"10.3390\/ijerph18041634","article-title":"Measuring activities of daily living in stroke patients using machine learning algorithms","volume":"18","author":"Chen","year":"2021","journal-title":"Int J Environ Res Public Health"},{"key":"R3-20260416","doi-asserted-by":"crossref","first-page":"e21795","DOI":"10.1097\/MD.0000000000021795","article-title":"The impact of dysphagia on quality of life in stroke patients","volume":"99","author":"Kim","year":"2020","journal-title":"Medicine (Baltimore)"},{"key":"R4-20260416","first-page":"2907293","article-title":"Effectiveness of Conventional Swallowing Therapy in Acute Stroke Patients with Dysphagia","author":"Jongprasitkul","year":"2020","journal-title":"Rehabil Res Pract"}],"container-title":["Journal of Pharmacy and Bioallied Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_18_26","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:43:24Z","timestamp":1787067804000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_18_26"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":4,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/jpbs.jpbs_18_26","relation":{},"ISSN":["0976-4879","0975-7406"],"issn-type":[{"value":"0976-4879","type":"print"},{"value":"0975-7406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2026-01-10","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-30","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}