{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T20:24:48Z","timestamp":1787775888637,"version":"build-2784847793"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 1","license":[{"start":{"date-parts":[[2025,4,17]],"date-time":"2025-04-17T00:00:00Z","timestamp":1744848000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:p>This case study presents a 38-year-old female with a history of infertility complicated by severe cervical stenosis and intramural fibroids, which rendered traditional transcervical embryo transfer (ET) ineffective. After previously failed cycles of in vitro fertilization, the couple was advised for transmyometrial embryo transfer (TMET), an invasive technique that places the embryo straight into the lining of the endometrium rather than through the cervix. Full assessment showed appropriate hormone levels and normospermia excluding the presence of male factor infertility. The patient received ovarian stimulation, oocyte retrieval, and ET through TMET. After the procedure, progesterone supplementations were given to sustain the luteal phase. A beta hCG test returned a positive result after 2 weeks of the transfer confirming pregnancy. This case illustrates the effectiveness of TMET in avoiding the anatomical issues associated with conventional ET and reinforces the concept of the need for customized fertility care.<\/jats:p>","DOI":"10.4103\/jpbs.jpbs_1918_24","type":"journal-article","created":{"date-parts":[[2025,4,17]],"date-time":"2025-04-17T04:00:11Z","timestamp":1744862411000},"page":"S986-S989","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Addressing Cervical Stenosis and Uterine Fibroids in IVF: A Case Study on the Effectiveness of TMET"],"prefix":"10.4103","volume":"17","author":[{"given":"Shradha","family":"Ulhe","sequence":"first","affiliation":[{"name":"School of Allied Health Sciences, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Namrata","family":"Choudhary","sequence":"additional","affiliation":[{"name":"School of Allied Health Sciences, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akash","family":"More","sequence":"additional","affiliation":[{"name":"School of Allied Health Sciences, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sudhanshu","family":"Dakre","sequence":"additional","affiliation":[{"name":"School of Allied Health Sciences, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,4,17]]},"reference":[{"key":"R1-20250513","doi-asserted-by":"crossref","first-page":"1640","DOI":"10.1016\/j.ijnurstu.2015.05.004","article-title":"Gender differences in experiences with and adjustments to infertility: A literature review","volume":"52","author":"Ying","year":"2015","journal-title":"Int J Nurs Stud"},{"key":"R2-20250513","doi-asserted-by":"crossref","first-page":"768363","DOI":"10.3389\/fendo.2022.768363","article-title":"Thyroid autoimmunity in female infertility and assisted reproductive technology outcome","volume":"13","author":"Bucci","year":"2022","journal-title":"Front Endocrinol"},{"key":"R3-20250513","first-page":"306","article-title":"Sperm DNA fragmentation: Causes, evaluation and management in male infertility","volume":"28","author":"Andrabi","year":"2024","journal-title":"JBRA Assist Reprod"},{"key":"R4-20250513","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.3390\/diagnostics11081455","article-title":"Uterine fibroids and infertility","volume":"11","author":"Freytag","year":"2021","journal-title":"Diagnostics"},{"key":"R5-20250513","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1007\/s00404-023-07126-1","article-title":"Uterine cervical stenosis: From classification to advances in management. Overcoming the obstacles to access the uterine cavity","volume":"309","author":"Vitale","year":"2023","journal-title":"Arch Gynecol Obstet"},{"key":"R6-20250513","doi-asserted-by":"crossref","first-page":"65","DOI":"10.4103\/jhrs.JHRS_88_19","article-title":"Live birth following transmyometrial embryo transfer","volume":"13","author":"Arora","year":"2020","journal-title":"J Hum Reprod Sci"},{"key":"R7-20250513","doi-asserted-by":"crossref","first-page":"e116","DOI":"10.15557\/JoU.2020.0019","article-title":"Cervical stenosis and pregnancy rate after ultrasound guided cervical dilation in women undergoing saline infusion sonography","volume":"20","author":"Izhar","year":"2020","journal-title":"J Ultrason"},{"key":"R8-20250513","doi-asserted-by":"crossref","first-page":"2045","DOI":"10.1093\/humrep\/dead194","article-title":"Infertility in patients with uterine fibroids: A debate about the hypothetical mechanisms","volume":"38","author":"Don","year":"2023","journal-title":"Hum Reprod"},{"key":"R9-20250513","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1016\/j.bj.2021.06.009","article-title":"Hysteroscopic cervical features associated with difficult embryo transfer in unselected patients undergoing in vitro fertilization","volume":"45","author":"Ou","year":"2022","journal-title":"Biomed J"},{"key":"R10-20250513","doi-asserted-by":"crossref","first-page":"deae108.767","DOI":"10.1093\/humrep\/deae108.767","article-title":"P-417 Transmyometrial embryo transfer as a reliable alternative to challenging transcervical embryo transfer","volume":"39","author":"Kothari","year":"2024","journal-title":"Hum Reprod"}],"container-title":["Journal of Pharmacy and Bioallied Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_1918_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:45:03Z","timestamp":1787773503000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_1918_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,17]]},"references-count":10,"journal-issue":{"issue":"Suppl 1","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/jpbs.jpbs_1918_24","relation":{},"ISSN":["0976-4879","0975-7406"],"issn-type":[{"value":"0976-4879","type":"print"},{"value":"0975-7406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,17]]},"assertion":[{"value":"2024-12-17","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-12-30","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}