{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T20:30:50Z","timestamp":1787776250677,"version":"build-2784847793"},"reference-count":17,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 1","license":[{"start":{"date-parts":[[2025,2,15]],"date-time":"2025-02-15T00:00:00Z","timestamp":1739577600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:p>One of the biggest health issues facing women in their childbearing years worldwide is polycystic ovarian syndrome, or PCOS. PCOS is a prevalent endocrine condition with well-known negative effects on metabolism, reproduction, and cardiovascular health that contribute to substantial morbidity. There are still many unanswered questions regarding the precise mechanisms by which PCOS arises, and research into the disorder\u2019s nature is ongoing. This study aims to investigate this uncharted horizon of PCOS by analyzing association between serum Caspase-1, IL-10, and biochemical indices relative to insulin resistance (HOMA-IR), hyperandrogenism (FAI), dyslipidemia, and oxidative stress in our female population. It expands on the significance of inflammation and insulin resistance, together with dyslipidemia in the advancement and signs and symptoms of PCOS. The work\u2019s preface highlights the goal of advancing medical science\u2019s ability to treat patients with illnesses and makes the case that interdisciplinary cooperation between gynecology, endocrinology, and biochemistry improves patient care. Our objective is to identify potential strategies to lessen the effects of PCOS in order to enhance the results of its diagnostic, therapeutic, and preventative measures for the millions of women who are affected.<\/jats:p>","DOI":"10.4103\/jpbs.jpbs_1995_24","type":"journal-article","created":{"date-parts":[[2025,2,15]],"date-time":"2025-02-15T14:00:12Z","timestamp":1739628012000},"page":"S130-S132","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Review on: Women with Polycystic Ovary Syndrome"],"prefix":"10.4103","volume":"17","author":[{"given":"Neelam","family":"Gusain","sequence":"first","affiliation":[{"name":"Department of Biochemistry, Jawaharlal Nehru Medical College, DMIHER (DU), Sawangi (M), Wardha, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashish P.","family":"Anjankar","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Jawaharlal Nehru Medical College, DMIHER (DU), Sawangi (M), Wardha, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ranjit S.","family":"Ambad","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Jawaharlal Nehru Medical College, DMIHER (DU), Sawangi (M), Wardha, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roshan K.","family":"Jha","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Jawaharlal Nehru Medical College, DMIHER (DU), Sawangi (M), Wardha, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rakesh","family":"Jha","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Jawaharlal Nehru Medical College, DMIHER (DU), Sawangi (M), Wardha, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,2,15]]},"reference":[{"key":"R1-20250513","doi-asserted-by":"crossref","first-page":"1454","DOI":"10.3390\/jcm12041454","article-title":"Polycystic ovary syndrome: Etiology, current management, and future therapeutics","volume":"12","author":"Singh","year":"2023","journal-title":"J Clin Med"},{"key":"R2-20250513","first-page":"1","article-title":"Epidemiology, diagnosis, and management of polycystic ovary syndrome","volume":"6","author":"Sirmans","year":"2014","journal-title":"Clin Epidemiol"},{"key":"R3-20250513","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1186\/s12967-023-04116-4","article-title":"The interplay between androgens and the immune response in polycystic ovary syndrome","volume":"21","author":"Shabbir","year":"2023","journal-title":"J Transl 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