{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:20:46Z","timestamp":1787840446552,"version":"build-2784847793"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 2","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,6]]},"abstract":"\n A\n BSTRACT<\/jats:sc>\n <\/jats:title>\n \n Background:<\/jats:title>\n Silver diamine fluoride (SDF) has emerged as an effective, noninvasive treatment for arresting dental caries. While its use has been extensively studied in pediatric populations, there is limited evidence regarding its effectiveness in adults.<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods:<\/jats:title>\n \n This prospective study was conducted on 100 adult patients aged 25\u201360 years with active caries lesions in posterior teeth. Participants were randomly divided into two groups: the experimental group received a single application of 38% SDF, while the control group received standard fluoride varnish. Caries arrest was assessed using visual-tactile examination and scored using the International Caries Detection and Assessment System criteria at baseline, 1 month, and 6 months. Patient satisfaction and side effects were also documented. Statistical analysis was performed using paired\n t<\/jats:italic>\n -tests and Chi-square tests, with a significance level set at\n P<\/jats:italic>\n < 0.05.\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n After 6 months, 85% of caries lesions in the SDF group were arrested, compared to 45% in the fluoride varnish group (\n P<\/jats:italic>\n < 0.001). Patient satisfaction scores were significantly higher in the SDF group, with a mean score of 4.7 compared to 3.5 in the control group. Minor side effects, such as temporary staining, were observed in 90% of SDF-treated teeth but were deemed acceptable by patients.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n The application of 38% SDF is highly effective in arresting caries in adult patients and provides a promising, minimally invasive treatment option. Although tooth staining remains a common side effect, its clinical benefits outweigh aesthetic concerns, making it a valuable tool in caries management.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/jpbs.jpbs_240_25","type":"journal-article","created":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T01:01:28Z","timestamp":1750208488000},"page":"S1288-S1290","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Effectiveness of Silver Diamine Fluoride in Arresting Caries in Adult Patients"],"prefix":"10.4103","volume":"17","author":[{"given":"Mohammed E.","family":"Rashid","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Diagnostic Sciences, College of Dentistry, Taibah University, Al Madinah Al Munawara, Kingdom of Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,6,18]]},"reference":[{"key":"R1-20250618","first-page":"315","article-title":"Promoting caries arrest in children with silver diamine fluoride: A review","volume":"6","author":"Chu","year":"2008","journal-title":"Oral Health Prev Dent"},{"key":"R2-20250618","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1016\/j.jdent.2012.08.002","article-title":"Randomized clinical trial on effectiveness of silver diamine fluoride and glass ionomer in arresting dentin caries in preschool children","volume":"40","author":"Zhi","year":"2012","journal-title":"J Dent"},{"key":"R3-20250618","first-page":"93","article-title":"Clinical use of silver diamine fluoride in dental treatment","volume":"37","author":"Mei","year":"2016","journal-title":"Compend Contin Educ Dent"},{"key":"R4-20250618","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1111\/idj.12007","article-title":"Minimal intervention dentistry for managing dental caries \u2013A review","volume":"62","author":"Frencken","year":"2012","journal-title":"Int Dent J"},{"key":"R5-20250618","first-page":"98","article-title":"Evidence-based practice: A silver-fluoride bullet for caries?","volume":"24","author":"Crystal","year":"2012","journal-title":"Adv Dent Res"},{"key":"R6-20250618","first-page":"201","article-title":"Clinical trials of silver diamine fluoride in arresting caries among children: A systematic review","volume":"1","author":"Gao","year":"2016","journal-title":"JDR Clin Trans Res"},{"key":"R7-20250618","first-page":"22","article-title":"Effectiveness of silver diamine fluoride in caries prevention and arrest: A systematic literature review","volume":"65","author":"Contreras","year":"2017","journal-title":"Gen Dent"},{"key":"R8-20250618","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1177\/0022034509338671","article-title":"Efficacy of silver diamine fluoride for arresting caries treatment","volume":"88","author":"Yee","year":"2009","journal-title":"J Dent Res"},{"key":"R9-20250618","first-page":"455","article-title":"An innovative approach to treating caries in populations with limited access to dental care","volume":"22","author":"Targino","year":"2014","journal-title":"J Appl Oral Sci"},{"key":"R10-20250618","first-page":"16","article-title":"UCSF protocol for caries arrest using silver diamine fluoride: Rationale, indications, and consent","volume":"44","author":"Horst","year":"2016","journal-title":"J Calif Dent Assoc"}],"container-title":["Journal of Pharmacy and Bioallied Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_240_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T13:22:49Z","timestamp":1787836969000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_240_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":10,"journal-issue":{"issue":"Suppl 2","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/jpbs.jpbs_240_25","relation":{},"ISSN":["0976-4879","0975-7406"],"issn-type":[{"value":"0976-4879","type":"print"},{"value":"0975-7406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"2025-01-27","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-02-13","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}