{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T20:24:17Z","timestamp":1787775857282,"version":"build-2784847793"},"reference-count":13,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 1","license":[{"start":{"date-parts":[[2025,4,12]],"date-time":"2025-04-12T00:00:00Z","timestamp":1744416000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:p>This case report presents a 36-year-old man with elongated sperm morphology, a specific type of teratozoospermia, associated with oxidative stress and deoxyribonucleic acid (DNA) damage. Six months of supplementation of L-carnitine, acetyl-L-carnitine, CoQ10, zinc, and vitamins, combined with lifestyle modifications enhanced sperm motility, morphology, and quality significantly. Posttreatment semen analysis showed improved concentration (13\u201320 million\/mL), progressive motility (25%\u201340%), and normal morphology (2%\u20137%). The couple underwent intracytoplasmic morphologically selected sperm injection (IMSI), leading to successful fertilization, production of high-quality embryos, and confirmed pregnancy. This case illuminates the therapeutic potential of L-carnitine and acetyl-L-carnitine supplementation, in combination with IMSI, in treating male infertility associated with abnormal sperm morphology and improving outcomes of assisted reproductive technology.<\/jats:p>","DOI":"10.4103\/jpbs.jpbs_256_25","type":"journal-article","created":{"date-parts":[[2025,4,14]],"date-time":"2025-04-14T08:00:14Z","timestamp":1744617614000},"page":"S1038-S1041","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["L-Carnitine and Acetyl-L-Carnitine: A Novel Approach to Treating Male Infertility with Abnormal Sperm Morphology"],"prefix":"10.4103","volume":"17","author":[{"given":"Lakhan Parsharam","family":"Padwal","sequence":"first","affiliation":[{"name":"Department of Clinical Embryology, School of Allied Health Sciences, Datta Meghe Institute of Higher Education and Research, Sawangi (Meghe), Wardha, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akash","family":"More","sequence":"additional","affiliation":[{"name":"Department of Clinical Embryology, School of Allied Health Sciences, Datta Meghe Institute of Higher Education and Research, Sawangi (Meghe), Wardha, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Namrata","family":"Choudhary","sequence":"additional","affiliation":[{"name":"Department of Clinical Embryology, School of Allied Health Sciences, Datta Meghe Institute of Higher Education and Research, Sawangi (Meghe), Wardha, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ganesh Laxman","family":"Kalasakar","sequence":"additional","affiliation":[{"name":"Department of Clinical Embryology, School of Allied Health Sciences, Datta Meghe Institute of Higher Education and Research, Sawangi (Meghe), Wardha, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tejaswini","family":"Wadhe","sequence":"additional","affiliation":[{"name":"Department of Clinical Embryology, School of Allied Health Sciences, Datta Meghe Institute of Higher Education and Research, Sawangi (Meghe), Wardha, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,4,12]]},"reference":[{"key":"R1-20250513","first-page":"508","article-title":"Infertility and sexual dysfunctions: A systematic literature review","volume":"58","author":"Starc","year":"2019","journal-title":"Acta Clin Croat"},{"key":"R2-20250513","doi-asserted-by":"crossref","first-page":"945351","DOI":"10.3389\/frph.2022.945351","article-title":"The relevance of sperm morphology in male infertility","volume":"4","author":"Moretti","year":"2022","journal-title":"Front Reprod 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