{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T00:29:24Z","timestamp":1793147364372,"version":"4.5.0"},"reference-count":8,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 2","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,6]]},"abstract":"\n A\n BSTRACT<\/jats:sc>\n <\/jats:title>\n \n Background:<\/jats:title>\n Plantar fasciitis, a chronic inflammatory condition characterized by heel pain, significantly impacts daily functioning. While corticosteroid injections are a common treatment, they are associated with limitations such as short-term efficacy and potential complications.<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods:<\/jats:title>\n \n This prospective interventional study was conducted at Mahatma Gandhi Medical College and Research Institute, Puducherry, between August 2022 and May 2024. A total of 60 patients diagnosed with plantar fasciitis, aged 18\u201370 years, were randomly divided into two groups: the platelet-rich plasma (PRP) group (30 patients) and the corticosteroid group (30 patients). PRP therapy was administered using the peppering technique, while the corticosteroid group received 80 mg methylprednisolone injections. Pain and functional outcomes were assessed at baseline, second, fourth, eighth, and 12\n th<\/jats:sup>\n weeks using the visual analog scale (VAS) and Foot and Ankle Ability Measure (FAAM).\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n The mean age of participants was 47.30 \u00b1 10.75 years in the PRP group and 46.13 \u00b1 10.58 years in the corticosteroid group. Females constituted 53.3% of the PRP group and 60% of the corticosteroid group. Significant reductions in VAS scores were observed in the PRP group compared to the corticosteroid group at the second week (5.53 \u00b1 0.776 vs. 6.47 \u00b1 0.937,\n P<\/jats:italic>\n < 0.001), fourth week (4.70 \u00b1 0.466 vs. 5.27 \u00b1 0.868,\n P<\/jats:italic>\n = 0.003), and 12\n th<\/jats:sup>\n week (2.10 \u00b1 0.712 vs. 2.77 \u00b1 0.858,\n P<\/jats:italic>\n = 0.002). Functional improvement, measured by FAAM scores, was significantly greater in the PRP group at the 12\n th<\/jats:sup>\n week (91.03 \u00b1 3.943 vs. 86.13 \u00b1 6.388,\n P<\/jats:italic>\n = 0.001).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n PRP therapy is a superior alternative to corticosteroid injections for the management of plantar fasciitis, providing sustained pain relief and improved functional outcomes over a 12-week period. Further large-scale, long-term studies are recommended to validate these findings.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/jpbs.jpbs_263_25","type":"journal-article","created":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T01:01:28Z","timestamp":1750208488000},"page":"S1689-S1691","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":4,"title":["A Comparative Study of Platelet-Rich Plasma V\/S Corticosteroid Injection for Plantar Fasciitis"],"prefix":"10.4103","volume":"17","author":[{"given":"Het","family":"Shah","sequence":"first","affiliation":[{"name":"Department of Orthopaedics, Mahatma Gandhi Medical College and Research Institute, Sri Balaji Vidyapeeth, Pondicherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Prabhakaran","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Mahatma Gandhi Medical College and Research Institute, Sri Balaji Vidyapeeth, Pondicherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iyyappan","family":"Praveen","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Mahatma Gandhi Medical College and Research Institute, Sri Balaji Vidyapeeth, Pondicherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Umar","family":"Farook","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Mahatma Gandhi Medical College and Research Institute, Sri Balaji Vidyapeeth, Pondicherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,6,18]]},"reference":[{"key":"R1-20250618","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.foot.2015.08.006","article-title":"Platelet-rich plasma versus corticosteroid injection for plantar fasciitis: A comparative study","volume":"25","author":"Jain","year":"2015","journal-title":"Foot (Edinb)"},{"key":"R2-20250618","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1186\/s12891-023-06277-1","article-title":"Effect of platelet-rich plasma versus steroid injection in plantar fasciitis: A randomized clinical trial","volume":"24","author":"Sharma","year":"2023","journal-title":"BMC Musculoskelet Disord"},{"key":"R3-20250618","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1177\/1071100713519778","article-title":"Platelet-rich plasma efficacy versus corticosteroid injection treatment for chronic severe plantar fasciitis","volume":"35","author":"Monto","year":"2014","journal-title":"Foot Ankle Int"},{"key":"R4-20250618","doi-asserted-by":"crossref","first-page":"e8475","DOI":"10.1097\/MD.0000000000008475","article-title":"Platelet-rich plasma as a treatment for plantar fasciitis: A meta-analysis of randomized controlled trials","volume":"96","author":"Yang","year":"2017","journal-title":"Medicine (Baltimore)"},{"issue":"(Suppl 1)","key":"R5-20250618","first-page":"142","article-title":"Role of platelet rich plasma in chronic plantar fasciitis: A prospective study","volume":"55","author":"Kalia","year":"2020","journal-title":"Indian J Orthop"},{"key":"R6-20250618","doi-asserted-by":"crossref","first-page":"50","DOI":"10.22271\/ortho.2020.v6.i1r.3011","article-title":"A comparative prospective study of platelet-rich plasma vs. corticosteroid injection in plantar fasciitis","volume":"6","author":"Gautam","year":"2020","journal-title":"Int J Orthop Sci"},{"key":"R7-20250618","doi-asserted-by":"crossref","first-page":"79","DOI":"10.22271\/ortho.2022.v8.i1b.2991","article-title":"A comparative study to analyze the efficacy of platelet-rich plasma versus corticosteroids in the treatment of chronic plantar fasciitis","volume":"8","author":"Senthilnathan","year":"2022","journal-title":"Int J Orthop Sci"},{"key":"R8-20250618","doi-asserted-by":"crossref","first-page":"187","DOI":"10.4103\/jmsr.jmsr_81_20","article-title":"Effectiveness of single injection of platelet-rich plasma over corticosteroid in the treatment of plantar fasciitis \u2013A randomized, comparative study","volume":"4","author":"Sahoo","year":"2020","journal-title":"J Musculoskelet Surg Res"}],"container-title":["Journal of Pharmacy and Bioallied Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_263_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T13:22:51Z","timestamp":1787836971000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_263_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":8,"journal-issue":{"issue":"Suppl 2","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/jpbs.jpbs_263_25","relation":{},"ISSN":["0976-4879","0975-7406"],"issn-type":[{"value":"0976-4879","type":"print"},{"value":"0975-7406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"2025-01-28","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-02-10","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}