{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T19:21:47Z","timestamp":1791573707919,"version":"4.3.4"},"reference-count":16,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Orthodontic treatment can alter the oral environment, leading to plaque accumulation and changes in microbial colonization. This study aimed to assess microbiological changes in 10 to 16-year-old children undergoing fixed orthodontic treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methodology:<\/jats:title>\n                    <jats:p>The study included children aged 10\u201316 years, with one group wearing fixed orthodontic appliances and a control group without brackets. Data on salivary pH, buffer capacity, Streptococcus mutans, and Lactobacillus spp were collected at baseline and after 6 months. Logistic regression models evaluated associations between orthodontic treatment and elevated bacterial levels, adjusting for age, gender, pH, and buffer capacity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Wearing fixed orthodontic appliances was significantly associated with elevated Streptococcus mutans (aOR: 6.62, 95% CI: 1.91\u201321.88) and Lactobacillus spp (aOR: 9.49, 95% CI: 2.57\u201335.07). Gender showed a significant association with Lactobacillus spp levels (aOR: 0.28, 95% CI: 0.09\u20130.87).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Fixed orthodontic appliances significantly impact oral microbial changes, underscoring the need for proper oral hygiene during orthodontic treatment to reduce dental caries risk.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jpbs.jpbs_303_24","type":"journal-article","created":{"date-parts":[[2024,5,25]],"date-time":"2024-05-25T11:00:07Z","timestamp":1716634807000},"page":"S2353-S2355","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":7,"title":["Effect of Fixed Orthodontic Appliances on Oral Microbial Changes and Dental Caries Risk in Children: A 6-Month Prospective Study"],"prefix":"10.4103","volume":"16","author":[{"given":"Subhash","family":"Chandra","sequence":"first","affiliation":[{"name":"Department of Orthodontics and Dentofacial Orthopedics, Dental Institute, RIMS, Ranchi, Jharkhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Awanindra K.","family":"Jha","sequence":"additional","affiliation":[{"name":"Department of Orthodontics and Dentofacial Orthopedics, Dental Institute, RIMS, Ranchi, Jharkhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saeed N.","family":"Asiri","sequence":"additional","affiliation":[{"name":"Department of Preventive Dental Sciences, College of Dentistry, Prince Sattam Bin AbdulAziz University, Al-Kharj, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atri","family":"Naik","sequence":"additional","affiliation":[{"name":"Department of Dentistry, NaMo Medical Education and Research Institute Silvassa U.T., DNH & DD, 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