{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:20:38Z","timestamp":1787840438230,"version":"build-2784847793"},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 2","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Pit and fissure sealants are widely used as a preventive measure against dental caries, especially in high-risk populations. Various types of sealants, including resin-based, glass ionomer, and bioactive materials, have been introduced with differing levels of retention and caries prevention efficacy. This study evaluates and compares the effectiveness of different sealant materials in preventing occlusal caries in a community-based setting.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>A total of 400 school-aged children (6\u201312 years) were enrolled and randomly assigned to three groups based on the type of pit and fissure sealant used: Group A (resin-based sealant), Group B (glass ionomer sealant), and Group C (bioactive sealant). The sealants were applied following manufacturer instructions, and retention rates along with caries incidence were assessed at 6 and 12 months. Statistical analysis was performed using Chi-square tests and ANOVA to determine significant differences between groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      At the 6-month follow-up, retention rates were highest in Group A (85%), followed by Group C (80%) and Group B (70%). At 12 months, retention declined to 75%, 72%, and 60% for Groups A, C, and B, respectively. Caries incidence after one year was lowest in Group A (7%), followed by Group C (9%) and Group B (15%), with statistically significant differences (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.05). Resin-based and bioactive sealants demonstrated superior retention and caries prevention compared to glass ionomer sealants.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>All three types of sealants provided caries prevention benefits, but resin-based and bioactive sealants exhibited better retention and efficacy over time. Community-based programs should prioritize these materials for effective long-term caries prevention in children. Further research is needed to assess cost-effectiveness and long-term outcomes in diverse populations.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jpbs.jpbs_332_25","type":"journal-article","created":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T01:01:26Z","timestamp":1750208486000},"page":"S1761-S1763","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Evaluation of Different Pit and Fissure Sealants for Caries Prevention in Community Settings"],"prefix":"10.4103","volume":"17","author":[{"given":"Abdulraheem A.","family":"Alwafi","sequence":"first","affiliation":[{"name":"Department of Dental Public Health, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,6,18]]},"reference":[{"key":"R2-20250618","first-page":"393","article-title":"Pit and fissure sealant: Review of the literature","volume":"24","author":"Simonsen","year":"2002","journal-title":"Pediatr Dent"},{"key":"R3-20250618","doi-asserted-by":"crossref","first-page":"257","DOI":"10.14219\/jada.archive.2008.0155","article-title":"Evidence-based clinical recommendations for the use of pit-and-fissure sealants","volume":"139","author":"Beauchamp","year":"2008","journal-title":"J Am Dent Assoc"},{"key":"R4-20250618","first-page":"CD001830","article-title":"Sealants for preventing dental decay in permanent teeth","volume":"7","author":"Ahovuo-Saloranta","year":"2017","journal-title":"Cochrane Database Syst Rev"},{"key":"R5-20250618","doi-asserted-by":"crossref","first-page":"31","DOI":"10.14219\/jada.archive.1987.0199","article-title":"Retention and effectiveness of a single application of white sealant after 10 years","volume":"115","author":"Simonsen","year":"1987","journal-title":"J Am Dent Assoc"},{"key":"R6-20250618","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1111\/j.1600-0528.2006.00319.x","article-title":"Retention of resin-based pit and fissure sealants: A systematic review","volume":"34","author":"M\u00fcller-Bolla","year":"2006","journal-title":"Community Dent Oral Epidemiol"},{"key":"R7-20250618","first-page":"196","article-title":"Glass ionomer cements as restorative materials in primary dentition: A systematic review","volume":"38","author":"Raggio","year":"2010","journal-title":"J Dent"},{"key":"R8-20250618","first-page":"904","article-title":"Retention and caries-preventive effect of glass ionomer and resin-based sealants: An 18-month-randomized clinical trial","volume":"34","author":"Al-Jobair","year":"2015","journal-title":"Dent Mater J"},{"key":"R9-20250618","first-page":"178","article-title":"Bioactive polymeric dental materials","volume":"6","author":"Skrtic","year":"1996","journal-title":"Curr Opin Dent"},{"key":"R10-20250618","doi-asserted-by":"crossref","first-page":"S409","DOI":"10.4103\/jpbs.jpbs_529_22","article-title":"Dentists' utilization of caries risk assessment and individualized caries prevention methods in pediatric patients in Saudi Arabia","volume":"15","author":"Asali","year":"2023","journal-title":"J Pharm Bioallied Sci"}],"container-title":["Journal of Pharmacy and Bioallied Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_332_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T13:22:49Z","timestamp":1787836969000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_332_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":9,"journal-issue":{"issue":"Suppl 2","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/jpbs.jpbs_332_25","relation":{},"ISSN":["0976-4879","0975-7406"],"issn-type":[{"value":"0976-4879","type":"print"},{"value":"0975-7406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"2025-02-01","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-02-13","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}