{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T23:51:29Z","timestamp":1789775489015,"version":"4.0.1"},"reference-count":8,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 2","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Early childhood caries (ECC) remains a significant public health concern affecting young children worldwide. Community-based fluoride varnish programs have been widely implemented as a preventive strategy. However, variations in application frequency and program delivery models necessitate an evaluation of their comparative effectiveness in reducing ECC prevalence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>\n                      A total of 450 children aged 3\u20135 years were enrolled and divided into three groups based on the fluoride varnish application frequency: Group A (once every six months), Group B (once every three months), and Group C (once every two months). The study was conducted over one year in community health centers and preschools. Caries prevalence was assessed at baseline and after 12 months using the decayed, missing, and filled teeth (dmft) index. Statistical analysis was performed using paired\n                      <jats:italic toggle=\"yes\">t<\/jats:italic>\n                      -tests and ANOVA to compare mean dmft scores among the groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      At baseline, the mean dmft scores were 4.2 \u00b1 1.3 for Group A, 4.0 \u00b1 1.2 for Group B, and 4.1 \u00b1 1.1 for Group C, with no significant differences (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &gt; 0.05). After one year, Group A showed a mean reduction in dmft score to 3.5 \u00b1 1.1, Group B to 2.8 \u00b1 0.9, and Group C to 2.1 \u00b1 0.8, with Group C demonstrating the most significant reduction (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.05). Regular fluoride varnish applications every two months showed the greatest effectiveness in reducing caries incidence.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Community-based fluoride varnish programs effectively reduce ECC prevalence, with more frequent applications yielding better outcomes. Implementing fluoride varnish every two months may be the most effective strategy for caries prevention in preschool children. These findings highlight the importance of structured fluoride application protocols in community dental health programs.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jpbs.jpbs_333_25","type":"journal-article","created":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T01:01:37Z","timestamp":1750208497000},"page":"S1764-S1766","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Effectiveness of Various Community-Based Fluoride Varnish Programs on Early Childhood Caries"],"prefix":"10.4103","volume":"17","author":[{"given":"Layla Waleed","family":"Abuljadayel","sequence":"first","affiliation":[{"name":"Department of Dental Public Health, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,6,18]]},"reference":[{"key":"R1-20250618","first-page":"CD002279","article-title":"Fluoride varnishes for preventing dental caries in children and adolescents","volume":"7","author":"Marinho","year":"2013","journal-title":"Cochrane Database Syst Rev"},{"key":"R2-20250618","first-page":"527","article-title":"The effectiveness of fluoride varnish in preventing dental caries in children","volume":"82","author":"Weintraub","year":"2003","journal-title":"J Dent Res"},{"key":"R3-20250618","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1034\/j.1601-0825.2001.70202.x","article-title":"The use of fluoride varnishes in the prevention of dental caries: A short review","volume":"7","author":"Strohmenger","year":"2001","journal-title":"Oral Dis"},{"issue":"(Suppl 1)","key":"R4-20250618","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1590\/S1806-83242010000500003","article-title":"Fluoride: Its role in dentistry","volume":"24","author":"Tenuta","year":"2010","journal-title":"Braz Oral Res"},{"key":"R5-20250618","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1177\/154405910608500211","article-title":"Fluoride varnish efficacy in preventing early childhood caries","volume":"85","author":"Weintraub","year":"2006","journal-title":"J Dent Res"},{"key":"R6-20250618","first-page":"308","article-title":"A 24-month study comparing the caries preventive effect of fluoride varnish, fluoride rinse, and fluoride toothpaste","volume":"31","author":"Bravo","year":"1997","journal-title":"Caries Res"},{"key":"R7-20250618","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1111\/j.1600-0528.1979.tb01225.x","article-title":"Effect of fluoride varnish (Duraphat) in preschool children","volume":"7","author":"Holm","year":"1979","journal-title":"Community Dent Oral Epidemiol"},{"issue":"(Suppl 1)","key":"R8-20250618","doi-asserted-by":"crossref","first-page":"S409","DOI":"10.4103\/jpbs.jpbs_529_22","article-title":"Dentists' utilization of caries risk assessment and individualized caries prevention methods in pediatric patients in Saudi Arabia","volume":"15","author":"Asali","year":"2023","journal-title":"J Pharm Bioallied Sci"}],"container-title":["Journal of Pharmacy and Bioallied Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_333_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T13:22:40Z","timestamp":1787836960000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_333_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":8,"journal-issue":{"issue":"Suppl 2","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/jpbs.jpbs_333_25","relation":{},"ISSN":["0976-4879","0975-7406"],"issn-type":[{"value":"0976-4879","type":"print"},{"value":"0975-7406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"2025-02-01","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-02-12","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}