{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:32:52Z","timestamp":1787070772993,"version":"build-2736575974"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 4","license":[{"start":{"date-parts":[[2024,10,21]],"date-time":"2024-10-21T00:00:00Z","timestamp":1729468800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:p>Brown tumor is a lesion that develops in patients with hyperparathyroidism. It can be described as the terminal stage of bone remodeling process where abnormal bone metabolism takes place. Hyperplasia or adenoma of the parathyroid glands is the main etiology of primary hyperparathyroidism (HPT). Due to overproduction of parathyroid hormone in hyperparathyroidism bone resorption takes place, which appear as cyst-like lesions, commonly known as osteitis fibrosa cystica or brown tumor. Any skeletal bones, including jawbones can be affected in this disorder. Most of the time brown tumor is detected after confirmatory diagnosis of hyperparathyroidism. Presentation of brown tumor as the first manifestation of this disorder is rare. In this present report, a large proliferative growth in left jaw with multilocular radiolucency in 23 years aged female was described as an unusual first manifestation of hyperparathyroidism.<\/jats:p>","DOI":"10.4103\/jpbs.jpbs_357_24","type":"journal-article","created":{"date-parts":[[2024,10,21]],"date-time":"2024-10-21T06:00:11Z","timestamp":1729490411000},"page":"S3679-S3682","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["A Large Brown Tumor of Mandible as First Manifestation of Hyperparathyroidism"],"prefix":"10.4103","volume":"16","author":[{"given":"Animesh","family":"Mondal","sequence":"first","affiliation":[{"name":"PGT (Oral and Maxillofacial Pathology and Microbiology), Dr. R. Ahmed Dental College and Hospital, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pratik","family":"Sarkar","sequence":"additional","affiliation":[{"name":"PGT (Oral and Maxillofacial Pathology and Microbiology), Dr. R. Ahmed Dental College and Hospital, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tathagata","family":"Bhattacharjee","sequence":"additional","affiliation":[{"name":"Associate Professor, Department of Oral Pathology and Microbiology, Dr. R. Ahmed Dental College and Hospital, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandip","family":"Ghose","sequence":"additional","affiliation":[{"name":"Associate Professor, Department of Oral Pathology and Microbiology, Dr. R. Ahmed Dental College and Hospital, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jay G","family":"Ray","sequence":"additional","affiliation":[{"name":"Professor and HOD, Department of Oral Pathology and Microbiology, Dr. R. Ahmed Dental College and Hospital, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,10,21]]},"reference":[{"key":"R1-20241227","first-page":"163","article-title":"A brown tumor secondary to hyperparathyroidism in the maxilla, skull, scapula, and femora","volume":"34","author":"Psaila","year":"2020","journal-title":"Proc (Bayl Univ Med Cent)"},{"key":"R2-20241227","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.12998\/wjcc.v12.i7.1200","article-title":"Expect the unexpected: Brown tumor of the mandible as the first manifestation of primary hyperparathyroidism","volume":"12","author":"Majic Tengg","year":"2024","journal-title":"World J Clin Cases"},{"key":"R3-20241227","doi-asserted-by":"crossref","first-page":"7370","DOI":"10.3390\/ijerph18147370","article-title":"Mandibular brown tumor as a result of secondary hyperparathyroidism: A case report with 5 years follow-up and review of the literature","volume":"18","author":"Shavlokhova","year":"2021","journal-title":"Int J Environ Res Public Health"},{"key":"R4-20241227","first-page":"50","article-title":"Brown tumor of mandible in association with primary hyperparathyroidism: A case report","volume":"7","author":"Shetty","year":"2015","journal-title":"J Int Oral Health"},{"key":"R5-20241227","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1159\/000444703","article-title":"Brown tumors: A case report and review of the literature","volume":"6","author":"Can","year":"2016","journal-title":"Case Rep Nephrol Dial"},{"key":"R6-20241227","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.sdentj.2010.11.003","article-title":"Mandibular brown tumor as the first manifestation of primary hyperparathyroidism: A case report","volume":"23","author":"Alhusban","year":"2011","journal-title":"Saudi Dent J"},{"key":"R7-20241227","first-page":"41","article-title":"Simultaneous maxillary and mandibular brown tumors in secondary hyperparathyroidism: A case report","volume":"5","author":"Movahedian","year":"2008","journal-title":"Dent Res J"},{"key":"R8-20241227","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1259\/dmfr\/81694583","article-title":"Brown tumour of the maxilla and mandible: A rare complication of tertiary hyperparathyroidism","volume":"38","author":"Selvi","year":"2009","journal-title":"Dentomaxillofac Radiol"},{"key":"R9-20241227","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1007\/s10006-008-0105-9","article-title":"Bilateral maxillary brown tumours as the first presentation of primary hyperparathyroidism","volume":"12","author":"Jebasingh","year":"2008","journal-title":"Oral Maxillofac Surg"},{"key":"R10-20241227","doi-asserted-by":"crossref","first-page":"56","DOI":"10.4103\/0973-029X.80027","article-title":"Bilateral maxillary brown tumors in a patient with primary hyperparathyroidism: Report of a rare entity and review of literature","volume":"15","author":"Soundarya","year":"2011","journal-title":"J Oral Maxillofac Pathol"}],"container-title":["Journal of Pharmacy and Bioallied Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_357_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:36:22Z","timestamp":1787067382000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_357_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,21]]},"references-count":10,"journal-issue":{"issue":"Suppl 4","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/jpbs.jpbs_357_24","relation":{},"ISSN":["0976-4879","0975-7406"],"issn-type":[{"value":"0976-4879","type":"print"},{"value":"0975-7406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10,21]]},"assertion":[{"value":"2024-04-04","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-09-09","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}