{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:20:47Z","timestamp":1787840447943,"version":"build-2784847793"},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 2","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,6]]},"abstract":"\n A\n BSTRACT<\/jats:sc>\n <\/jats:title>\n \n Background:<\/jats:title>\n Pulp therapy in pediatric endodontics is crucial for maintaining primary teeth until natural exfoliation. Vital pulp therapy (VPT) and non-vital pulp therapy (NVPT) are commonly employed based on pulp status.<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods:<\/jats:title>\n \n A total of 80 pediatric patients (aged 4\u201310 years) with deep carious lesions were randomly assigned into two groups: VPT (\n n<\/jats:italic>\n = 40) and NVPT (\n n<\/jats:italic>\n = 40). VPT included indirect pulp capping, direct pulp capping, and pulpotomy, while NVPT involved pulpectomy followed by obturation. Success rates were assessed through clinical signs (pain, swelling, mobility) and radiographic parameters over 12 months. Statistical analysis was performed using the Chi-square test with significance set at\n P<\/jats:italic>\n < 0.05.\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n At the 12-month follow-up, the VPT group showed an 85% success rate, while NVPT had an 80% success rate. Failure in VPT was mainly due to secondary infection and internal resorption, whereas NVPT failures were attributed to periapical pathology and root resorption. The difference in outcomes was not statistically significant (\n P<\/jats:italic>\n = 0.36).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Both VPT and NVPT are effective in managing deep caries in pediatric patients, with comparable success rates. VPT remains a preferable option in cases of reversible pulpitis due to its conservative nature, whereas NVPT is essential in cases of irreversible pulpitis.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/jpbs.jpbs_393_25","type":"journal-article","created":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T01:01:47Z","timestamp":1750208507000},"page":"S1799-S1801","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Comparative Analysis of Vital and Nonvital Pulp Therapy Outcomes in Pediatric Endodontics"],"prefix":"10.4103","volume":"17","author":[{"given":"R","family":"Venkatasubramanian","sequence":"first","affiliation":[{"name":"Department of Pediatric and Preventive Dentistry, Dayananda Sagar College of Dental Sciences, Kumaraswamy Layout, Bangalore, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B. K","family":"Ramnarayan","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine and Radiology, Dayananda Sagar College of Dental Sciences, Kumaraswamy Layout, Bangalore, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krishnanand P.","family":"Satelur","sequence":"additional","affiliation":[{"name":"Department of Oral Pathology, Dayananda Sagar College of Dental Sciences, Kumaraswamy Layout, Bangalore, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Avinash","sequence":"additional","affiliation":[{"name":"Department of Public Health Dentistry, Dayananda Sagar College of Dental Sciences, Kumaraswamy Layout, Bangalore, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Hemanth","sequence":"additional","affiliation":[{"name":"Department of Orthodontics, Dayananda Sagar college of Dental Sciences, Kumaraswamy Layout, Bangalore, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vidya M.","family":"Annegowda","sequence":"additional","affiliation":[{"name":"Department of Oral Pathology, Dayananda Sagar College of Dental Sciences, Kumaraswamy Layout, Bangalore, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,6,18]]},"reference":[{"key":"R1-20250618","first-page":"337","article-title":"Use of Non-Vital Pulp Therapies in Primary Teeth","volume":"42","author":"Coll","year":"2020","journal-title":"Pediatr Dent"},{"issue":"(7 Suppl)","key":"R2-20250618","doi-asserted-by":"crossref","first-page":"S18","DOI":"10.1016\/j.joen.2008.02.031","article-title":"Vital pulp therapy with new materials for primary teeth: New directions and treatment perspectives","volume":"34","author":"Fuks","year":"2008","journal-title":"J Endod"},{"key":"R3-20250618","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1016\/j.joen.2005.12.008","article-title":"A prospective clinical study of mineral trioxide aggregate for partial pulpotomy in cariously exposed permanent teeth","volume":"32","author":"Barrieshi-Nusair","year":"2006","journal-title":"J Endod"},{"key":"R4-20250618","doi-asserted-by":"crossref","first-page":"1560","DOI":"10.12688\/f1000research.16142.2","article-title":"Pulpotomy versus pulpectomy in the treatment of vital pulp exposure in primary incisors. A systematic review and meta-analysis","volume":"7","author":"Gadallah","year":"2018","journal-title":"F1000Res"},{"key":"R5-20250618","first-page":"347","article-title":"Evaluation of various root canal filling materials in primary molar pulpectomies: An in vivo study","volume":"18","author":"Ozalp","year":"2005","journal-title":"Am J Dent"},{"key":"R6-20250618","first-page":"129","article-title":"Long-term evaluation of pulpotomy in primary molars using mineral trioxide aggregate or formocresol","volume":"27","author":"Holan","year":"2005","journal-title":"Pediatr Dent"},{"issue":"(Suppl 1)","key":"R7-20250618","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1111\/j.1365-263X.2006.00774.x","article-title":"Pulp therapy for primary molars","volume":"16","author":"Rodd","year":"2006","journal-title":"Int J Paediatr Dent"},{"key":"R8-20250618","first-page":"118","article-title":"Primary tooth pulp therapy as taught in predoctoral pediatric dental programs in the United States","volume":"19","author":"Primosch","year":"1997","journal-title":"Pediatr Dent"},{"key":"R9-20250618","first-page":"6","article-title":"A review on vital pulp therapy in primary teeth","volume":"10","author":"Parisay","year":"2015","journal-title":"Iran Endod J"}],"container-title":["Journal of Pharmacy and Bioallied Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_393_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T13:22:55Z","timestamp":1787836975000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_393_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":9,"journal-issue":{"issue":"Suppl 2","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/jpbs.jpbs_393_25","relation":{},"ISSN":["0976-4879","0975-7406"],"issn-type":[{"value":"0976-4879","type":"print"},{"value":"0975-7406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"2025-02-04","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-02-16","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}