{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T17:23:25Z","timestamp":1787765005649,"version":"build-2784847793"},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,2]]},"abstract":"\n A\n BSTRACT<\/jats:sc>\n <\/jats:title>\n \n Objective:<\/jats:title>\n This research assessed the efficiencies of aloe vera, 0.1% triamcinolone acetonide, and 5% amlexanox in the management of OLP.<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods:<\/jats:title>\n A total of 120 participants diagnosed with oral lichen planus (OLP) were equally divided into three groups and treated with: aloe vera, (Group A), 0.1% triamcinolone acetonide (Group B), and 5% amlexanox (Group C) topical medicaments. The patients were evaluated for pain, using the visual analogue scale (VAS). They were also evaluated for ulcerative lesion type and erosive area on days 1, 7, and 15 of the study.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n There was a statistically considerable decrease in the VAS pain scale score, reduction in the erosive area on buccal mucosa, and healing of ulcer from day 1\n st<\/jats:sup>\n to 15\n th<\/jats:sup>\n day with all three tested drugs.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n All drugs used in this study; aloe vera, triamcinolone acetonide, and amlexanox were effective in treating OLP patients.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/jpbs.jpbs_416_23","type":"journal-article","created":{"date-parts":[[2023,12,22]],"date-time":"2023-12-22T08:00:48Z","timestamp":1703232048000},"page":"S133-S135","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":6,"title":["Efficacy of Aloe Vera, Amlexanox (5%), and Triamcinolone Acetonide (0.1%) in the Management of Oral Lichen Planus"],"prefix":"10.4103","volume":"16","author":[{"given":"Manpreet","family":"Kaur","sequence":"first","affiliation":[{"name":"Associate Professor, Department of Oral Pathology, Maharishi Markandeshwar College of Dental Sciences and Research (Deemed to be University) Mullana, Haryana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prerna","family":"Gulati","sequence":"additional","affiliation":[{"name":"Professor and Head, Department of Public Health Dentistry, Guru Nanak Dev Dental College and Research Institute, Sunam, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sugandha","family":"Verma","sequence":"additional","affiliation":[{"name":"Senior Resident, Department of Oral Medicine and Radiology, Dental College, Rajendra Institute of Medical Sciences, Ranchi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Parul","family":"Khare","sequence":"additional","affiliation":[{"name":"Assistant Professor, Department of Oral & Maxillofacial Pathology & Oral Microbiology, School of Dental Sciences, Sharda University, Greater Noida, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruchi","family":"Garg","sequence":"additional","affiliation":[{"name":"Associate Professor, Department of Public Health Dentistry, Swami Devi Dyal Hospital and Dental College, Barwala, Panchkula, Haryana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jahnobi","family":"Dutta","sequence":"additional","affiliation":[{"name":"Reader, Department of Oral and Maxillofacial Pathology, Government Dental College, Dibrugarh, Assam, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kumuda","family":"Rao","sequence":"additional","affiliation":[{"name":"Nitte (Deemed to be University), AB Shetty Memorial Institute of Dental Sciences, Department of Oral Medicine and Radiology, Deralakatte, Mangalore, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,12,20]]},"reference":[{"key":"R1-20240829","first-page":"367","article-title":"Efficacy of topical use of amlexanox and fluocinolone acetonide gels in the treatment of oral lichen planus","volume":"47","author":"Shennawy","year":"2001","journal-title":"Egypt Dent J"},{"key":"R2-20240829","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/S1079-2104(97)90010-X","article-title":"5% amlexanox oral paste, a new treatment for recurrent minor aphthous ulcers:II. Pharmacokinetics and demonstration of clinical safety","volume":"83","author":"Khandwala","year":"1997","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"R3-20240829","first-page":"23","article-title":"Amlexanox in the treatment of recurrent minor aphthous ulcers","volume":"3","author":"Katti","year":"2011","journal-title":"Int J Dent Clin."},{"issue":"Suppl 1","key":"R4-20240829","doi-asserted-by":"crossref","first-page":"S86","DOI":"10.4103\/0975-7406.191976","article-title":"A randomized triple-blind clinical trial to compare the effectiveness of topical triamcinolone acetonate (0.1%), clobetasol propionate (0.05%), and tacrolimus orabase (0.03%) in the management of oral lichen planus","volume":"8","author":"Sivaraman","year":"2016","journal-title":"J Pharm Bioallied Sci"},{"key":"R5-20240829","doi-asserted-by":"crossref","first-page":"377","DOI":"10.2334\/josnusd.50.377","article-title":"Steriods in the treatment of lichen planus:A review","volume":"50","author":"Thongprasom","year":"2008","journal-title":"J Oral Sci"},{"key":"R6-20240829","doi-asserted-by":"crossref","first-page":"593","DOI":"10.4103\/0970-9290.123382","article-title":"A clinical evaluation of 5% amlexanox oral paste in the treatment of minor recurrent aphthous ulcers and comparison with the placebo paste:A randomized, vehicle controlled, parallel, single center clinical trial","volume":"24","author":"Bhat","year":"2013","journal-title":"Indian J Dent Res"},{"key":"R7-20240829","first-page":"4","article-title":"Efficacy of aloe vera and clobetasol propionate in the management of oral lichen planus:A randomized parallel clinical trial","volume":"20","author":"Vaidya","year":"2023","journal-title":"Front Dent"},{"key":"R8-20240829","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1186\/s12903-021-01652-7","article-title":"Malignant transformation of oral lichen planus:A retrospective study of 565 Japanese patients","volume":"21","author":"Tsushima","year":"2021","journal-title":"BMC Oral Health"},{"key":"R9-20240829","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1016\/j.oooo.2011.10.013","article-title":"Amlexanox is as effective as dexamethasone in topical treatment of erosive oral lichen planus:A short-term pilot study","volume":"113","author":"Fu","year":"2012","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol"}],"container-title":["Journal of Pharmacy and Bioallied Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_416_23","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:55:48Z","timestamp":1787763348000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_416_23"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,20]]},"references-count":9,"journal-issue":{"issue":"Suppl 1","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/jpbs.jpbs_416_23","relation":{},"ISSN":["0976-4879","0975-7406"],"issn-type":[{"value":"0976-4879","type":"print"},{"value":"0975-7406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,12,20]]},"assertion":[{"value":"2023-07-16","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-07-24","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}