{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T23:36:57Z","timestamp":1792712217903,"version":"4.5.0"},"reference-count":15,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:p>Internal root resorption (IRR) commonly occurs as a single oval-shaped defect radiographically; however, variation like bilocular IRR defect is rarely reported in the literature. This case report presents a 28-year-old male patient who reported with pain of dull nature, in his front upper tooth for the past 1 week. He reported with a history of trauma 8 years back. Clinical findings indicated the maxillary left central incisor with a crown, tender to percussion and palpation, no swelling, mobility, or pockets were noted. A tentative diagnosis of symptomatic apical periodontitis was made. The diagnosis was confirmed through careful, clinical, and radiographic examination, including the use of cone-beam computed tomography for detailed morphology. Radiographic examination revealed an oval-shaped radiolucency in the midroot region of tooth #21. The bilocular nature of the IRR defect was revealed in the different views of the CBCT. Given the challenges in cleaning, shaping, disinfecting, and obturating, the IRR defect, a specialized endodontic approach, was employed. The use of passive ultrasonic irrigation (PUI) for canal disinfection and hybrid technique of obturation with bioceramic sealer led to the reinforcing the IRR defect, and the successful outcome has a 4-year follow-up.<\/jats:p>","DOI":"10.4103\/jpbs.jpbs_444_24","type":"journal-article","created":{"date-parts":[[2024,8,2]],"date-time":"2024-08-02T02:39:43Z","timestamp":1722566383000},"page":"S3005-S3008","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Nonsurgical Endodontic Management of Nonperforating Internal Root Resorption in a Maxillary Central Incisor: A Case Report with a 4-Year Follow-Up"],"prefix":"10.4103","volume":"16","author":[{"given":"Paras M.","family":"Gehlot","sequence":"first","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics, JSS Dental College and Hospital, JSS Academy of Higher Education and Research (JSSAHER), JSS Medical Institutions Campus, Sri Shivarathreeshwara Nagara, Mysuru, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Divya S.","family":"Rajkumar","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics, JSS Dental College and Hospital, JSS Academy of Higher Education and Research (JSSAHER), JSS Medical Institutions Campus, Sri Shivarathreeshwara Nagara, Mysuru, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annapoorna B.","family":"Mariswamy","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics, JSS Dental College and Hospital, JSS Academy of Higher Education and Research (JSSAHER), JSS Medical Institutions Campus, Sri Shivarathreeshwara Nagara, Mysuru, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Upendra Natha N.","family":"Reddy","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics, G. Pulla Reddy Dental College and Hospital, Kurnool, Andrapradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chaitanya","family":"Chappidi","sequence":"additional","affiliation":[{"name":"Department of Dentistry, NMC Speciality Hospital, Al Ain, UAE"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,7,31]]},"reference":[{"issue":"Suppl 4","key":"R1-20240829","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1111\/iej.13715","article-title":"Present status and future directions: Root resorption","volume":"55","author":"Patel","year":"2022","journal-title":"Int Endod J"},{"key":"R2-20240829","doi-asserted-by":"crossref","first-page":"368504221109217","DOI":"10.1177\/00368504221109217","article-title":"Tooth root resorption: A review","volume":"105","author":"Heboyan","year":"2022","journal-title":"Sci Prog"},{"key":"R3-20240829","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1111\/aej.12436","article-title":"Management of a perforating internal root resorption using mineral trioxide aggregate: A case report with 5-year follow-up","volume":"46","author":"Pereira","year":"2020","journal-title":"Aust Endod J"},{"key":"R4-20240829","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1111\/aej.12275","article-title":"Stress distributions in internal resorption cavities restored with different materials at different root levels: A finite element analysis study","volume":"45","author":"Aslan","year":"2019","journal-title":"Aust Endod J"},{"key":"R5-20240829","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1111\/edt.12757","article-title":"Tooth resorption-part 1: The evolvement, rationales and controversies of tooth resorption","volume":"38","author":"Lin","year":"2022","journal-title":"Dent Traumatol"},{"key":"R6-20240829","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1186\/s12903-021-01510-6","article-title":"Pathophysiological mechanisms of root resorption after dental trauma: A systematic scoping review","volume":"21","author":"Galler","year":"2021","journal-title":"BMC Oral Health"},{"key":"R7-20240829","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s41121-020-00020-4","article-title":"Applications of cone beam computed tomography in endodontics","volume":"5","author":"Khanna","year":"2020","journal-title":"Evid Based Endod"},{"key":"R8-20240829","first-page":"211","article-title":"Diagnostic accuracy of high resolution cone-beam computed tomography and standard mode cone-beam computed tomography in internal root resorption","volume":"14","author":"Mahmoudi","year":"2019","journal-title":"Iran Endod J"},{"key":"R9-20240829","first-page":"3130813","article-title":"Effect of passive ultrasonic irrigation over organic tissue of simulated internal root resorption","author":"Abu","year":"2021","journal-title":"Int J Dent 2021"},{"key":"R10-20240829","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1002\/cre2.573","article-title":"Evaluation of pH and calcium ion release at the simulated external root resorption cavities of teeth obturated with bioceramic sealer","volume":"8","author":"Angkasuvan","year":"2022","journal-title":"Clin Exp Dent Res"},{"key":"R11-20240829","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1007\/s40368-020-00597-9","article-title":"Effect of mineral trioxide aggregate and biodentine\u2122 on fracture resistance of immature teeth dentine over time: In vitro study","volume":"22","author":"Yasin","year":"2021","journal-title":"Eur Arch Paediatr Dent"},{"key":"R12-20240829","first-page":"6","article-title":"Evaluation of fracture resistance of roots-filled with various root canal sealers at different time periods","volume":"53","author":"Uzunoglu","year":"2019","journal-title":"Eur Oral Res"},{"key":"R13-20240829","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1186\/s12967-023-04550-4","article-title":"Clinical application of calcium silicate-based bioceramics in endodontics","volume":"21","author":"Wang","year":"2023","journal-title":"J Transl Med"},{"key":"R14-20240829","doi-asserted-by":"crossref","first-page":"e35","DOI":"10.5395\/rde.2020.45.e35","article-title":"Calcium silicate-based root canal sealers: A literature review","volume":"45","author":"Lim","year":"2020","journal-title":"Restor Dent Endod"},{"key":"R15-20240829","first-page":"21","article-title":"Comparing the ability of different materials and techniques in filling artificial internal resorption cavities","volume":"4","author":"Yazdi","year":"2019","journal-title":"Eur Endod J"}],"container-title":["Journal of Pharmacy and Bioallied Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_444_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:00:33Z","timestamp":1787839233000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jpbs.jpbs_444_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":15,"journal-issue":{"issue":"Suppl 3","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/jpbs.jpbs_444_24","relation":{},"ISSN":["0976-4879","0975-7406"],"issn-type":[{"value":"0976-4879","type":"print"},{"value":"0975-7406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7]]},"assertion":[{"value":"2024-04-15","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-05-15","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}