{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:34:19Z","timestamp":1787762059109,"version":"build-2784847793"},"reference-count":14,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>The aim of the current research was to assess the effectiveness of different remineralizing substances on artificial white spot lesions on deciduous teeth.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>\n                      45 deciduous teeth without dental caries constituted the study group for this\n                      <jats:italic toggle=\"yes\">in vitro<\/jats:italic>\n                      research. A 3 mm by 3 mm window of enamel was uncovered at the occluso-gingival midpoint of the coronal labial surface; an acid-resistant nail varnish was coated alongside the uncovered enamel surface of all specimens, employing vertical strokes. Demineralization was executed for the tenure of 72 hours at 37\u00b0C temperature in an incubator. The forty-five specimens, fifteen in each group, were assigned to the investigational groups plus a control group as: Group A: Control, Group B: Calcium sucrose phosphate (CaSP), Group C: Casein phosphopeptide\u2013amorphous calcium phosphate\u2013fluoride (CPP-ACPF). Microhardness tester was employed for testing the microhardness of the enamel surface using a Vickers diamond indenter laden with twenty-five milligrams for approximately ten seconds. Vickers hardness number (VHN) calculations for the microhardness were performed at baseline and on the fourteenth day.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The CPP-ACPF group exhibited greater mean microhardness value at 236.14 \u00b1 2.12, in pursuit by CaSP group with a score of 231.98 \u00b1 3.16 and then the control group at 220.22 \u00b1 5.08. An extremely statistically significant difference was seen amid the groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The current research arrived at a conclusion that both the remineralizing substances were certainly efficient in handling early dental caries, and additionally, casein phosphopeptide\u2013amorphous calcium phosphate\u2013fluoride (CPP-ACPF) was found highly efficient as a remineralizing substance, in pursuit by calcium sucrose phosphate (CaSP).<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jpbs.jpbs_485_22","type":"journal-article","created":{"date-parts":[[2023,7,12]],"date-time":"2023-07-12T02:07:24Z","timestamp":1689127644000},"page":"S426-S429","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Impact of Various Remineralizing Agents on Artificial White Spot Lesion on Primary Teeth\u2014A Comparative Study"],"prefix":"10.4103","volume":"15","author":[{"given":"Abdulhamid","family":"Al Ghwainem","sequence":"first","affiliation":[{"name":"Assistant Professor of Pediatric Dentistry, Department of Preventive Dental Sciences, College of Dentistry, Prince Sattam Bin Abdulaziz University, Alkharj, Kingdom of Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,7,5]]},"reference":[{"key":"R1-20240829","doi-asserted-by":"crossref","first-page":"375","DOI":"10.4103\/0972-0707.114347","article-title":"Evaluation to determine the caries remineralization potential of three dentifrices:An in vitro study","volume":"16","author":"Balakrishnan","year":"2013","journal-title":"J Conserv Dent"},{"key":"R2-20240829","doi-asserted-by":"crossref","first-page":"16","DOI":"10.3126\/kumj.v12i1.13627","article-title":"Effect of three different remineralizing agents on enamel caries formation-an in vitro 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of a calcium sucrose phosphate based toothpaste in elevating the level of calcium, phosphate ions in saliva and reducing plaque:A clinical trial","volume":"9","author":"Menon","year":"2018","journal-title":"Contemp Clin Dent"},{"key":"R13-20240829","doi-asserted-by":"crossref","first-page":"176","DOI":"10.4103\/0970-9290.159154","article-title":"Comparative evaluation of two different remineralizing agents on the microhardness of bleached enamel surface:Results of an in vitro study","volume":"26","author":"Kaur","year":"2015","journal-title":"Indian J Dent Res"},{"key":"R14-20240829","doi-asserted-by":"crossref","first-page":"309","DOI":"10.4103\/jispcd.JISPCD_67_18","article-title":"In vitro comparison of antimicrobial activity of conventional fluoride varnishes containing xylitol and casein phosphopeptide-amorphous calcium phosphate","volume":"8","author":"Jafari","year":"2018","journal-title":"J Int Soc Prev Community Dent"}],"container-title":["Journal of Pharmacy and Bioallied 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